Patents by Inventor Boaz Kigel

Boaz Kigel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING SEMAPHORINS FOR THE TREATMENT OF CANCER AND METHODS OF SELECTION THEREOF
    Publication number: 20180055907
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Application
    Filed: November 5, 2017
    Publication date: March 1, 2018
    Applicant: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
    Inventors: Gera NEUFELD, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • Compositions comprising semaphorins for the treatment of cancer and methods of selection thereof
    Patent number: 9808506
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: November 7, 2017
    Assignee: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
    Inventors: Gera Neufeld, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • COMPOSITIONS COMPRISING SEMAPHORINS FOR THE TREATMENT OF CANCER AND METHODS OF SELECTION THEREOF
    Publication number: 20160263182
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Application
    Filed: September 8, 2015
    Publication date: September 15, 2016
    Inventors: Gera NEUFELD, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
    Patent number: 9155781
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Methods of treating angiogenesis, kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: October 13, 2015
    Assignee: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
    Inventors: Gera Neufeld, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • HIGH AFFINITY MOLECULES CAPABLE OF BINDING A TYPE A PLEXIN RECEPTOR AND USES OF SAME
    Publication number: 20130330349
    Abstract: A high affinity molecule is provided. The high affinity molecule comprises a binding domain which binds a type-A plexin receptor, wherein said binding domain inhibits proliferative signals through said type-A plexin receptor but does not interfere with binding of a neuropilin or semaphorin 6A to said type-A plexin receptor.
    Type: Application
    Filed: February 23, 2012
    Publication date: December 12, 2013
    Applicant: Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Gera Neufeld, Boaz Kigel, Noa Rabinowicz, Asya Varshavsky, Ofra Kessler
  • COMPOSITIONS COMPRISING SEMAPHORINS FOR THE TREATMENT OF ANGIOGENESIS RELATED DISEASES AND METHODS OF SELECTION THEREOF
    Publication number: 20130287726
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Methods of treating angiogenesis, kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Application
    Filed: July 15, 2013
    Publication date: October 31, 2013
    Inventors: Gera NEUFELD, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
    Patent number: 8513194
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Methods of treating angiogenesis, kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: August 20, 2013
    Assignee: Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Gera Neufeld, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • COMPOSITIONS COMPRISING SEMAPHORINS FOR THE TREATMENT OF ANGIOGENESIS RELATED DISEASES AND METHODS OF SELECTION THEREOF
    Publication number: 20120101029
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Methods of treating angiogenesis, kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Application
    Filed: December 7, 2011
    Publication date: April 26, 2012
    Applicant: Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Gera Neufeld, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
    Patent number: 8088735
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Methods of treating angiogenesis, kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: January 3, 2012
    Assignee: Rappaport Family Institute for Research in the Medical Sciences
    Inventors: Gera Neufeld, Boaz Kigel, Ofra Kessler, Asya Varshavsky
  • COMPOSITIONS COMPRISING SEMAPHORINS FOR THE TREATMENT OF ANGIOGENESIS RELATED DISEASES AND METHODS OF SELECTION THEREOF
    Publication number: 20100247516
    Abstract: A method of selecting a semaphorin for treating cancer in a subject is disclosed. The method comprises determining an expression of a semaphorin receptor on tumor cells of a tumor sample of the subject wherein an amount of the semaphorin receptor is indicative of the semaphorin suitable for treating the cancer in the subject. Methods of treating angiogenesis, kits for treating cancer and pharmaceutical compositions comprising semaphorins are also disclosed.
    Type: Application
    Filed: October 2, 2008
    Publication date: September 30, 2010
    Applicant: Rappaport Family Institute for Research Research in the Medical Sciences
    Inventors: Gera Neufeld, Boaz Kigel, Ofra Kessler, Asya Varshavsky