Patents by Inventor Bob Macel

Bob Macel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Magnesium omeprazole and process for its preparation
    Patent number: 6048981
    Abstract: Magnesium omeprazole is provided, in a form free of organic solvent residues and free of traces of more than 50 ppm of another metal ion. It is prepared by an aqueous phase process in which a solution of omeprazole in concentrated aqueous ammonia is added to a mixture of a magnesium salt and a fully ionized ammonium salt, in aqueous solution, to effect precipitation of magnesium omeprazole.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: April 11, 2000
    Assignee: Torcan Chemical Ltd.
    Inventor: Bob Macel
  • Sulfoxide-carboxylate intermediates of omeprazole and lansoprazole
    Patent number: 5502195
    Abstract: Omeprazole and lansoprazole, which are chemically pyridine-benzimidazole sulfinyl compounds, are produced from the corresponding acetamide-sulfide compounds by a process of oxidation to form the amide sulfinyl compound, followed by alkaline hydrolysis to the sulfinyl carboxylate or salt, and decarboxylation.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: March 26, 1996
    Inventors: Clarke Slemon, Bob Macel
  • Preparation of omeprazole and lansoprazole, and intermediates useful therein
    Patent number: 5470983
    Abstract: Omeprazole and lansoprazole, which are chemically pyridine-benzimidazole sulfinyl compounds, are produced from the corresponding acetamide-sulfide compounds by a process of oxidation to form the amide sulfinyl compound, followed by alkaline hydrolysis to the sulfinyl carboxylate or salt, and decarboxylation.
    Type: Grant
    Filed: July 18, 1994
    Date of Patent: November 28, 1995
    Assignee: Torcan Chemical Ltd.
    Inventors: Clarke Slemon, Bob Macel
  • Preparation of omeprazole and lansoprazole
    Patent number: 5374730
    Abstract: Omeprazole and lansoprazole, which are chemically pyridine-benzimidazole sulfinyl compounds, are produced from the corresponding acetamide-sulfide compounds by a process of oxidation to form the amide sulfinyl compound, followed by alkaline hydrolysis to the sulfinyl carboxylate or salt, and decarboxylation.
    Type: Grant
    Filed: November 4, 1993
    Date of Patent: December 20, 1994
    Assignee: Torcan Chemical Ltd.
    Inventors: Clarke Slemon, Bob Macel