Abstract: Anhydrous hydrocolloid matrices contain one or more encapsulated therapeutic agents, including an acne agent and/or skin conditioning agent. The anhydrous hydrocolloid matrices are used as acne treatment dressings alone or in a laminate with a water-impermeable or semi-water impermeable backing and a release liner. The anhydrous hydrocolloid matrices are made using a premix of viscosity modifiers and hydrocarbon emollients and the one or more therapeutic agents, which are mixed via high shear mixing to form the premix. The resulting anhydrous hydrocolloid matrices include the one or more therapeutic agents which are encapsulated and homogeneously distributed therein.

Abstract: Anhydrous hydrocolloid matrices contain one or more encapsulated therapeutic agents, including an acne agent and/or skin conditioning agent. The anhydrous hydrocolloid matrices are used as acne treatment dressings alone or in a laminate with a water-impermeable or semi-water impermeable backing and a release liner. The anhydrous hydrocolloid matrices are made using a premix of viscosity modifiers and hydrocarbon emollients and the one or more therapeutic agents, which are mixed via high shear mixing to form the premix. The resulting anhydrous hydrocolloid matrices include the one or more therapeutic agents which are encapsulated and homogeneously distributed therein.

Abstract: Anhydrous skin care compositions contain encapsulates, which in turn contain active agents, including retinol and/or bakuchiol. When formulated in a stick form and applied to the skin, the pressure applied to the stick during application deposits the skin care composition onto the skin. During application, some of the encapsulates contained in the composition collapse or rupture, releasing some of the retinol and/or bakuchiol payload onto the skin. As application continues, the encapsulates may break up into smaller particles that retain some of the payload of the active agent(s), which remain on the skin and deliver all or a portion of the retained payload to the skin over time, resulting in “extended release” of active agent(s) into the skin.

Abstract: A method and system for modifying a project model in response to an update. The project model including a plurality of activities, wherein each activities includes an early start date and a late finish date. A number of activities are initially added from the project model to a list in response to an update. Each activity added to the list is directly affected by the update. For early dates, an activity with an early start date that precedes all other early start dates with respect to other activities within the list is removed. Then, the early start date for the removed activity is redetermined in response to the update. Activities which succeed the removed activity and which are related to the activity to the list are added to the list if absence of a match between the redetermined early start date and the early start date associated with the removed activity exists.