Patents by Inventor Bodhan WASZKOWYCZ

Bodhan WASZKOWYCZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PARG inhibitory compounds
    Patent number: 10995073
    Abstract: The present invention relates to compounds of formula I that function as inhibitors of PARG (Poly ADP-ribose glycohydrolase) enzyme activity: wherein R1a, R1b, R1c, R1d, R1e, W, X1, X2, X3, X4, X5, X6, X7, c are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which PARG activity is implicated.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: May 4, 2021
    Assignee: Cancer Research Technology Limited
    Inventors: Alison E. McGonagle, Allan M. Jordan, Bodhan Waszkowycz, Colin P. Hutton, Ian D. Waddell, James R. Hitchin, Kate M. Smith, Niall M. Hamilton
  • PARG INHIBITORY COMPOUNDS
    Publication number: 20200165208
    Abstract: The present invention relates to compounds of formula I that function as inhibitors of PARG (Poly ADP-ribose glycohydrolase) enzyme activity: wherein R1a, R1b, R1c, R1d, R1e, W, X1, X2, X3, X4, X5, X6, X7, c are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which PARG activity is implicated.
    Type: Application
    Filed: October 24, 2019
    Publication date: May 28, 2020
    Inventors: Alison E. MCGONAGLE, Allan M. JORDAN, Bodhan WASZKOWYCZ, Colin P. HUTTON, Ian D. WADDELL, James R. HITCHIN, Kate M. SMITH, Niall M. HAMILTON