Abstract: New 8-substituted 2-aminotetralins can be prepared from the corresponding aminotetralins or tetralones. They can be used in medicaments.

Abstract: N-substituted derivatives of 1-desoxynojirimycin and 1-desoxymannojirimycin of the formula ##STR1## in which one of R and R' are hydroxyl and the other is hydrogenn is a number from 1 to 6R.sup.1 is hydrogen, alkyl or benzyl andR.sup.2 is alkyl which is optionally substituted by an optionally substituted aryl or by pyridyl, thienyl, furyl, pyrimidyl, pyrazinyl or quinolyl or R.sub.1 is cycloalkyl or R.sup.2 is optionally substituted by aryl or R.sup.2 is a saturated bridged heterocycle or R.sup.1 and R.sup.2 together can form a heterocyclic ring which is optionally substituted. These compounds are useful in the treatment of and prophylaxis of viral infections.

Abstract: Antithrombotic, antiatherosclerotic and antiischaemic compounds of the formula ##STR1## in which R.sup.1 is ##STR2## or SO.sub.2 R.sup.4, R.sup.3 is aryl, substituted aryl, heteroaryl, aralkyl or the group ##STR3## R.sup.4 is aryl or substrituted aryl, R.sup.2 is OH, alkoxy, phenoxy, benzoxy or NR.sup.5 R.sup.6, andR.sup.5 and R.sup.6 each independently is hydrogen or alkyl, orone of the radicals R.sup.5 or R.sup.6 is benzyl, and physiologically acceptable salts thereof with mono- and divalent cations.

Abstract: New 8-substituted 2-aminotetralins can be prepared from the corresponding aminotetralins or tetralones. They can be used in medicaments.

Abstract: Antithrombotic, antiatherosclerotic and antiischaemic compounds of the formula ##STR1## in which R.sup.1 is ##STR2## or SO.sub.2 R.sup.4, R.sup.3 is aryl, substituted aryl, heteroaryl, aralkyl or the group ##STR3## R.sup.4 is aryl or substituted aryl, R.sup.2 is OH, alkoxy, phenoxy, benzoxy or NR.sup.5 R.sup.6, andR.sup.5 and R.sup.6 each independently is hydrogen or alkyl, orone of the radicals R.sup.5 or R.sup.6 is benzyl,and physiologically acceptable salts thereof with mono- and divalent cations.

Abstract: A method of combating rheumatic diseases which comprises administering to a patient afflicted therewith an amount effective to combat such disease of a compound of the formula ##STR1## in which Z is a glycosyl radical bonded via the anomeric carbon atom,R.sub.1 is hydrogen or an optionally substituted hydrocarbon radical with up to 30 C atoms, which hydrocarbon radical is optionally interrupted by O, N or S, andR.sub.2 is hydrogen or an alkyl or aralkyl radical with up to 30 C atoms, which is optionally interrupted by O, N or S or substituted by an oxygen-containing group or halogen,with the proviso that COR.sub.1 is not an acyl group with 1-5 C atoms if R.sub.2 is alkyl with 10-20 C atoms.

Abstract: The invention includes certain 3,4,5-trihydroxypiperidine compounds, methods for their preparation, compositions containing said 3,4,5-trihydroxypiperidine compounds and methods for the use of said compounds and compositions.The subject matter of the invention is useful against diabetes, hyperlipaemia and adiposity as well as in animal nutrition.

Abstract: The invention relates to pharmaceutical compositions containing active ingredients of Formula (I) and methods for the use of said compositions to treat cardiac insufficiencies. Also included in the invention are methods of the manufacture of said active ingredients of Formula (I). The invention includes, additionally, compounds of Formula (I).

Abstract: Pyridoindoles of the formula ##STR1## in which R.sub.1 represents hydrogen or C.sub.1 -C.sub.4 -alkyl, which is optionally substituted by the radical ##STR2## R.sub.2 and R.sub.3 represent H or form a bond, or R.sub.1 and R.sub.2 together represent O, --O--CH.sub.2 --CH.sub.2 --O-- or --S--CH.sub.2 --CH.sub.2 --S--,R.sub.4 represents H or the ##STR3## or R.sub.3 and R.sub.4 represent O, orR.sub.1 and R.sub.4 are members of an N-containing six-membered ring andR.sub.8 and R.sub.9 represent H or C.sub.1 -C.sub.4 -alkyl, or optionally form, with the N atom, a heterocyclic 5-membered or 6-membered ring, which can optionally also contain a further hetero-atom from the series comprising N, O or S,R.sub.5 represents H, C.sub.1 -C.sub.4 -alkyl or the group ##STR4## or R.sub.5 and R.sub.3 form a bond, andR.sub.10 and R.sub.11 represent C.sub.1 -C.sub.4 -alkyl or are members of an N-containing 5-membered or 6-membered ring,R.sub.6 represents H or C.sub.1 -C.sub.4 -alkyl andR.sub.

Abstract: The invention relates to saturated aminocyclitol derivatives, as defined herein in Formula (F). Also included in the invention are methods for preparing said saturated aminocyclitol derivatives, compositions containing said saturated aminocyclitol derivatives and methods for the use of said compounds and compositions to provide inhibition of .alpha.-glycoside hydrolases.

Abstract: The invention relates, inter alia, to 3,4,5-trihydroxypiperidine compounds of Formula (I), infra, to methods for the manufacture of said compounds, to pharmaceutical compositions containing said compounds and to methods for the use of said compounds and compositions. Also included in the invention are concentrates, premixes and feedstuffs containing said compounds.

Abstract: The invention relates to 3,4,5-trihydroxypiperidine compound of Formula (I) as methods for the preparation of said compounds. Also included in the invention are compositions containing said piperidine compounds and methods for the use of said piperidine compounds and compositions. The invention further includes veterinary compositions containing said piperidine compounds and their use in animal nutrition.The piperidine compounds of Formula (I) are useful as agents against prediabetes, gastritis, constipation, infections of the gastro-intestinal tract, meteorism, flatulence, caries, arteriosclerosis and hypertension and in particular against diabetes, hyperlipaemia and adiposity, and also in animal nutrition for influencing the meat/fat ratio in favor of the meat content.

Abstract: The invention relates to 1-alka-2,4-dienyl-2-hydroxymethyl-3,4,5-trihydroxypiperidine compounds which are, inter alia, potent inhibitors for .alpha.- glucoside hydrolases and effect lipid absorption. Also included in the invention are methods for the manufacture of the said compounds, compositions containing said compounds and methods for the use of said compounds and compositions.

Abstract: The invention includes certain 3,4,5-trihydroxypiperidine compounds, methods for their preparation, compositions containing said 3,4,5-trihydroxypiperidine compounds and methods for the use of said compounds and compositions.The subject matter of the invention is useful against diabetes, hyperlipaemia and adiposity as well as in animal nutrition.

Abstract: The invention concerns the provision of novel 1,4-dihydropyridine-sugar derivatives and processes for their preparation. The invention also concerns pharmaceutical compositions containing the compounds of the invention and methods for their use. The products of the invention, such as 2-[1,4-dihydro-5-(2-propyl)-oxycarbonyl-2,6-dimethyl-4-m-nitrophenyl-3- pyridylcarbonyloxy]-ethyl .beta.-D-glucopyranoside, are effective for the treatment of circulatory disorders and can be used as antihypertensive agents, vasodilators or coronary therapeutic agents.

Abstract: The present invention provides amino-sugar derivatives of the general formula ##STR1## in which n and m independently of each other represent an integer from 0 to 8 and the sum n+m has a value of 0 to 8, andX designates a group --OR, --SH, --SR, --NH.sub.2, --NHR or NRR.sub.1,in whichR designates an alkyl, alkenyl, cycloalkyl, aralkyl, aryl or heterocyclic radical, which can be substituted, andR.sub.1 designates an alkyl, cycloalkyl, aralkyl or aryl radical, which can be substituted, orR and R.sub.1 together with the nitrogen atom to which they are bonded, form a heterocyclic ring.It has been found that the compounds of the formula (II) are highly active inhibitors for glycoside hydrolases of the digestive tract.Also included in the invention are methods of preparing the amino-sugar derivatives of the invention, compositions containing said amino-sugar derivatives and methods for the use of said amino-sugar derivatives and compositions containing them.

Abstract: New amino sugars which are glucopyranosyl and oligoglucosidyl derivatives of 4,6-bisdesoxy-4-(4,5,6-trihydroxy-3-hydroxymethylcyclohex-2-en-1-ylamin o)-.alpha.-D-glucopyranose inhibit glycoside hydrolases of the digestive tract. The compounds, of which O-{4,6-bisdesoxy-4-[1S-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxymethylcyclohex- 2-en-1-ylamino]-.alpha.-D-glucopyranosyl}-(1.fwdarw.4)-O-.alpha.-D-glucopyr anosyl-(1.fwdarw.4)-D-glucopyranose is a representative embodiment, demonstrate both saccharase and amylase inhibiting properties.