Patents by Inventor Bodo Levkau

Bodo Levkau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ligands for targeting of S1P receptors for in vivo imaging and treatment of diseases
    Patent number: 9345791
    Abstract: The present invention relates to novel compounds of formulae (I) and (II) which are useful in the prevention, treatment and diagnosis, in vivo diagnosis of diseases or disorders related to S1P receptors, in particular, in diseases which are connected to the regulatory function of sphingosine-1-phosphate (S1P) and its analogs, such as inflammation, pain, autoimmune diseases and cardiovascular diseases.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: May 24, 2016
    Assignee: Westfaelische Wilhelms-Universitaet Muenster
    Inventors: Guenter Haufe, Bodo Levkau, Michael Schaefers, Stefani Silke Schilson, Petra Keul
  • NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES
    Publication number: 20140170067
    Abstract: The present invention relates to novel compounds of formulae (I) and (II) which are useful in the prevention, treatment and diagnosis, in vivo diagnosis of diseases or disorders related to S1P receptors, in particular, in diseases which are connected to the regulatory function of sphingosine-1-phosphate (S1P) and its analogues, such as inflammation, pain, autoimmune diseases and cardiovascular diseases.
    Type: Application
    Filed: August 16, 2012
    Publication date: June 19, 2014
    Applicant: WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER
    Inventors: Guenter Haufe, Bodo Levkau, Michael Schaefers, Stefani Silke Schilson, Petra Keul
  • 5-pyrrolidinylsulfonyl isatin derivatives
    Patent number: 8440841
    Abstract: The present invention relates to novel 5-pyrrolidinylsulfonyl isatin derivatives, non-peptidyl Caspase binding Radioligands (CbRs) and CbR-transporter conjugates derived from said isatin derivatives, diagnostic compositions comprising said compounds of the invention and their use for non-invasive diagnostic imaging.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: May 14, 2013
    Assignee: Universitätsklinikum Münster
    Inventors: Klaus Kopka, Bodo Levkau, Michael Schäfers
  • Diagnostic imaging agents with MMP inhibitory activity
    Patent number: 8231858
    Abstract: The present invention relates to the field of diagnostic imaging. Specifically, the invention relates to the diagnostic imaging of diseases where specific matrix metalloproteinases are known to be involved. One embodiment of the invention is a compound having matrix metalloproteinase inhibitory activity suitable for diagnostic imaging. Also disclosed in the present invention is a pharmaceutical composition comprising the diagnostic imaging agent of the invention in a form suitable for mammalian administration. The invention furthermore discloses intermediates in the synthesis of the diagnostic imaging agents of the invention and kits for the preparation of the pharmaceutical composition of the invention. The pharmaceutical composition of the invention may be used in the diagnosis of diseases where specific matrix metalloproteinases are known to be involved.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: July 31, 2012
    Assignee: GE Healthcare Limited
    Inventors: Anthony Storey, Julie Davis, Sally-Ann Ricketts, Marivi Mendizabal, Alan Cuthbertson, Joseph Arukwe, Kirsty Heywood, Ian Wilson, Duncan Wynn, Michael Schafers, Bodo Levkau, Stefan Wagner, Hans-Jörg Breyholz, Klaus Kopka
  • 5-Pyrrolidinylsulfonyl Isatin Derivatives
    Publication number: 20090041664
    Abstract: The present invention relates to novel 5-pyrrolidinylsulfonyl isatin derivatives, non-peptidyl Caspase binding Radioligands (CbRs) and CbR-transporter conjugates derived from said isatin derivatives, diagnostic compositions comprising said compounds of the invention and their use for non-invasive diagnostic imaging.
    Type: Application
    Filed: December 22, 2005
    Publication date: February 12, 2009
    Inventors: Klaus Kopka, Bodo Levkau, Michael Schafers