Patents by Inventor Bogdan Czerniak

Bogdan Czerniak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-color fish test for bladder cancer detection
    Patent number: 11795512
    Abstract: The present disclosure provides methods and compositions for the detection of bladder in a subject using four locus-specific probes to 6p22, 8q22, 11q13, and 20p11.2.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: October 24, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Bogdan Czerniak, Keith Baggerly, Jolanta Bondaruk, Tadeusz Majewski, Colin Dinney, Shizhen Zhang, Yan Wang
  • MULTI-COLOR FISH TEST FOR BLADDER CANCER DETECTION
    Publication number: 20210230703
    Abstract: The present disclosure provides methods and compositions for the detection of bladder in a subject using four locus-specific probes to 6p22, 8q22, 11q13, and 20p11.2.
    Type: Application
    Filed: January 30, 2019
    Publication date: July 29, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Bogdan CZERNIAK, Keith BAGGERLY, Jolanta BONDARUK, Tadeusz MAJEWSKI, Colin DINNEY, Shizhen ZHANG, Yan WANG
  • NON-INVASIVE DETECTION OF BLADDER CANCER BY FLOURESCENCE IN SITU HIBRIDIZATION OF AURORA A
    Publication number: 20150315661
    Abstract: We disclose a method of detecting bladder cancer in a patient, comprising isolating bladder cells from the patient's urine; hybridizing the bladder cells with a labelled DNA probe, wherein the probe recognizes at least a portion of the aurora kinase A gene, to yield a sample of bladder cells hybridized with the labeled DNA probe: and counting the number of bladder cells in the sample, the number of copies of the aurora kinase A gene in each bladder cell in the sample, and the number of bladder cells in the sample having at least a first threshold number of copies of the aurora kinase A gene.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 5, 2015
    Applicant: Board of Regents, The University of Texas System
    Inventors: H. Barton Grossman, Bogdan Czerniak, Sen Subrata
  • METHODS OF CHARACTERIZING AND TREATING MOLECULAR SUBSET OF MUSCLE-INVASIVE BLADDER CANCER
    Publication number: 20150292030
    Abstract: The present application discloses a method of diagnostic testing of primary tumors, circulating tumor cells, serum, and urine to detect high-risk bladder cancers. These results have immediate implications for prognostication and the clinical management of muscle-invasive bladder cancer.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 15, 2015
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: David McConkey, Colin Dinney, Bogdan Czerniak, Keith Baggerly, Mai Tran, Woonyoung Choi, Neema Navai, Liana Adam, Arlene Siefker-Radtke, Matthew Wszolek
  • Detection of bladder cancer
    Patent number: 8609343
    Abstract: Provided are methods for detecting bladder cancer in a subject. In some aspects, methylation of one or more of MYO3A, CA10, NKX6-2, SOX11, DBC1, NPTX2, and/or A2BP1 in DNA sediment from a urine sample may be evaluated to detect the presence or absence of a bladder cancer in a human patient.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: December 17, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Woonbok Chung, Bogdan A. Czerniak, Jean-Pierre Issa
  • DETECTION OF BLADDER CANCER
    Publication number: 20120230952
    Abstract: Provided are methods for detecting bladder cancer in a subject. In some aspects, methylation of one or more of MYO3A, CA10, NKX6-2, SOX11, DBC1, NPTX2, and/or A2BP1 in DNA sediment from a urine sample may be evaluated to detect the presence or absence of a bladder cancer in a human patient.
    Type: Application
    Filed: March 12, 2012
    Publication date: September 13, 2012
    Inventors: Woonbok Chung, Bogdan A. Czerniak, Jean-Pierre Issa
  • Non-Invasive Detection of Bladder Cancer by Fluorescence in Situ Hybridization of Aurora A
    Publication number: 20100285486
    Abstract: We disclose a method of detecting bladder cancer in a patient, comprising isolating bladder cells from the patient's urine; hybridizing the bladder cells with a labelled DNA probe, wherein the probe recognizes at least a portion of the aurora kinase A gene, to yield a sample of bladder cells hybridized with the labeled DNA probe; and counting the number of bladder cells in the sample, the number of copies of the aurora kinase A gene in each bladder cell in the sample, and the number of bladder cells in the sample having at least a first threshold number of copies of the aurora kinase A gene.
    Type: Application
    Filed: December 12, 2008
    Publication date: November 11, 2010
    Inventors: H. Barton Grossman, Bogdan Czerniak, Sen Subrata
  • Methods of detecting, diagnosing and treating cancer and identifying neoplastic progression
    Publication number: 20030165895
    Abstract: Disclosed are methods, compositions and apparatus useful in the detection, monitoring and treatment of the progression of neoplasia and preneoplastic conditions with special emphasis on the chromosomal changes related to the development and progression of urothelial neoplasia. Chromosomal changes, including LOH, at the disclosed loci demonstrate a statistically significant relation to the progression of disease state in urothelial neoplasia.
    Type: Application
    Filed: June 11, 2002
    Publication date: September 4, 2003
    Inventors: Bogdan Czerniak, Dennis Johnston