Abstract: Labels that include dibromopyridazinedione attached to signal molecules are disclosed, along with methods of producing and using same. Also disclosed are conjugates of the label attached to an analyte-specific binder, as well as methods of producing and using same. Kits containing the labels and/or conjugates are also disclosed, along with microfluidics devices containing same.

Abstract: A system for controlling an electric brake for a wheel rotor having a brake pad associated therewith includes a housing defining a passage. An assembly is provided in the passage and includes a spindle rotatable about an axis and a piston aligned with the brake pad and axially movable in response to rotation of the spindle. A planetary gear stage includes a sun gear, a ring gear, and planetary gears. A first motor is coupled to the sun gear. A second motor coupled to the ring gear. A control system is configured to, in response to a detected braking event, rotate the first motor in a first direction to supply torque to the sun gear while the second motor is rotated in a second direction at varying speeds to supply torque to the ring gear such that the piston is cyclically moved towards and away from the brake pad to modulate a braking force on the rotor.

Abstract: A system for controlling an electric brake for a wheel rotor having a brake pad associated therewith includes a housing defining a passage. An assembly is provided in the passage and includes a spindle rotatable about an axis and a piston aligned with the brake pad and axially movable in response to rotation of the spindle. A planetary gear stage includes a sun gear, a ring gear, and planetary gears. A first motor is coupled to the sun gear. A second motor coupled to the ring gear. A control system is configured to, in response to a detected braking event, rotate the first motor in a first direction to supply torque to the sun gear while the second motor is rotated in a second direction at varying speeds to supply torque to the ring gear such that the piston is cyclically moved towards and away from the brake pad to modulate a braking force on the rotor.

Abstract: An actuator assembly for a vehicle brake is disclosed. The actuator assembly comprises, a carrier assembly, which comprises a first transmission plate and a second transmission plate, wherein the two transmission plates are connected to one another via a carrier component, are mounted in an actuator housing and carry a transmission unit. The first transmission plate has a fastening interface for an electric motor and is mounted in an elastically damped manner on the carrier component, and the second transmission plate is rigidly coupled to the carrier component.

Abstract: Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disclosed are methods of reducing naloxone or naltrexone interference in opiate assays using the antibodies.