Patents by Inventor Bogdan Zagribelnyy

Bogdan Zagribelnyy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SARS-COV-2 INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS
    Publication number: 20240025860
    Abstract: Provided herein are compounds, pharmaceutical compositions, and methods for treating a SARS-CoV-2 infection.
    Type: Application
    Filed: June 22, 2023
    Publication date: January 25, 2024
    Inventors: Xiao DING, Jingjing PENG, Feng REN, Xiaoyu DING, Bogdan ZAGRIBELNYY, Yan A. IVANENKOV
  • SARS-CoV-2 inhibitors for treating coronavirus infections
    Patent number: 11731944
    Abstract: Provided herein are compounds, pharmaceutical compositions, and methods for treating a SARS-CoV-2 infection.
    Type: Grant
    Filed: February 8, 2023
    Date of Patent: August 22, 2023
    Assignee: Insilico Medicine IP Limited
    Inventors: Xiao Ding, Jingjing Peng, Feng Ren, Xiaoyu Ding, Bogdan Zagribelnyy, Yan A. Ivanenkov
  • SARS-COV-2 INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS
    Publication number: 20230192624
    Abstract: Provided herein are compounds, pharmaceutical compositions, and methods for treating a SARS-CoV-2 infection.
    Type: Application
    Filed: February 8, 2023
    Publication date: June 22, 2023
    Inventors: Xiao DING, Jingjing PENG, Feng REN, Xiaoyu DING, Bogdan ZAGRIBELNYY, Yan A. IVANENKOV
  • SARS-COV-2 INHIBITORS HAVING COVALENT MODIFICATIONS FOR TREATING CORONAVIRUS INFECTIONS
    Publication number: 20230174488
    Abstract: Provided herein are compounds, pharmaceutical compositions and methods for treating a SARS-CoV-2 infection.
    Type: Application
    Filed: October 26, 2022
    Publication date: June 8, 2023
    Inventors: Aleksandrs Zavoronkovs, Yan A. Ivanenkov, Bogdan Zagribelnyy
  • RETROSYNTHESIS-RELATED SYNTHETIC ACCESSIBILITY
    Publication number: 20230154572
    Abstract: A method for training model to calculate synthetic accessibility includes: accessing molecule database and obtaining molecule; virtually slicing the molecule into fragments; determining a fragment frequency of fragments; calculating molecular descriptors for the fragments; calculating synthetic difficulty score for the molecule; and storing the synthetic difficulty score in a database. A method of evaluating molecular synthetic accessibility includes: selecting target molecule; decomposing the target molecule into molecular fragments; calculating a synthetic difficulty score for the molecular fragments for the target molecule; determining a sum of synthetic difficulty scores for the molecular fragments; determining a fragment density of the molecular fragments; calculating the synthetic accessibility score from the sum of synthetic difficulty scores and fragment densities; and providing the synthetic accessibility score for the target molecule.
    Type: Application
    Filed: May 11, 2021
    Publication date: May 18, 2023
    Inventors: Bogdan ZAGRIBELNYY, Evgeny Olegovich PUTIN, Sergei Andreevich FEDORCHENKO, Yan A. IVANENKOV, Aleksandrs ZAVORONKOVS
  • RETROSYNTHESIS SYSTEMS AND METHODS
    Publication number: 20220172802
    Abstract: A synthesis protocol for a reaction pathway of a target molecule can be determined by: providing target compound data; performing a chemical synthesis search for at least one reaction pathway for the target compound; processing the target compound data through a single-step reaction enumeration algorithm to obtain at least one reaction step of the least one reaction pathway; processing at least one reaction step with the at least one reaction pathway scoring mechanism model to obtain a reaction step score; constructing reaction pathways based on at least one reaction step and at least one reaction step score; providing a selectivity filter having a selectivity criteria; filtering the reaction pathways so that reactions violating the selectivity criteria is filtered out; ranking the reaction pathways; and providing the reaction pathway ranking.
    Type: Application
    Filed: November 29, 2021
    Publication date: June 2, 2022
    Inventors: Anton Konstantinov, Evgeny Olegovich Putin, Bogdan Zagribelnyy, Yan A. Ivanenkov, Aleksandrs Zavoronkovs