Patents by Inventor Bohong CHEN

Bohong CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRISPR-Cas systems and uses thereof
    Patent number: 12448630
    Abstract: Disclosed herein are a Cas12i polypeptide and use thereof in a CRISPR-Cas system. Specifically disclosed herein are a Cas12i polypeptide, a Cas12i fusion polypeptide, a guide RNA, a complex formed by the Cas12i polypeptide or fusion polypeptide with the guide RNA, a nucleic acid, a vector, a vector system, a delivery system, a kit, a composition, and a method for modifying a nucleic acid using the components described above.
    Type: Grant
    Filed: August 30, 2024
    Date of Patent: October 21, 2025
    Assignee: Lumiere Therapeutics Co., Ltd.
    Inventors: Bohong Chen, Yang Hu, Yulin Yu, Wenqiong Tan, Shaoyun Lin, Wenchang Xu, Youyu Wu, Xiaojie Ma, Jiajun Yu, Jinshuai Sun
  • CRISPR-CAS SYSTEMS AND USES THEREOF
    Publication number: 20250146023
    Abstract: Disclosed herein are a Cas12i polypeptide and use thereof in a CRISPR-Cas system. Specifically disclosed herein are a Cas12i polypeptide, a Cas12i fusion polypeptide, a guide RNA, a complex formed by the Cas12i polypeptide or fusion polypeptide with the guide RNA, a nucleic acid, a vector, a vector system, a delivery system, a kit, a composition, and a method for modifying a nucleic acid using the components described above.
    Type: Application
    Filed: August 30, 2024
    Publication date: May 8, 2025
    Inventors: Bohong CHEN, Yang HU, Yulin YU, Wenqiong TAN, Shaoyun LIN, Wenchang XU, Youyu WU, Xiaojie MA, Jiajun YU, Jinshuai SUN
  • Engineered adenosine deaminases and base editors thereof
    Patent number: 12129478
    Abstract: Disclosed are adenosine deaminases, base editors comprising the adenosine deaminases and complexes comprising the base editors. The adenosine deaminases and the base editors exhibited superior adenine editing effects and achieved A·T base pair to G·C base pair transformation at DNA level.
    Type: Grant
    Filed: August 28, 2023
    Date of Patent: October 29, 2024
    Assignee: Lumiere Therapeutics Co., Ltd.
    Inventors: Bohong Chen, Yang Hu, Yulin Yu, Shaoyun Lin, Wenqiong Tan
  • Adjustment method and device for chip output characteristics
    Patent number: 12002751
    Abstract: An adjustment method for the chip output characteristics can include the following steps. When adjusting the output characteristics of the chip to be tested, first it is determined whether the output characteristics of the chip to be tested have been adjusted according to the state of each E-fuse. When determining that the output characteristics of the chip to be tested have not been adjusted, the target adjustment solution corresponding to the chip is determined among a plurality of adjustment solutions in a targeted manner according to the output performance of the chip to be tested. The E-fuse in the chip to be tested is subjected to blowing treatment according to the target adjustment solution, so as to adjust the output characteristics of the chip to be tested.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: June 4, 2024
    Assignee: CHANGXIN MEMORY TECHNOLOGIES, INC.
    Inventors: Liang Chen, Yangyang Yin, Bohong Chen
  • ADJUSTMENT METHOD AND DEVICE FOR CHIP OUTPUT CHARACTERISTICS
    Publication number: 20220139830
    Abstract: An adjustment method for the chip output characteristics can include the following steps. When adjusting the output characteristics of the chip to be tested, first it is determined whether the output characteristics of the chip to be tested have been adjusted according to the state of each E-fuse. When determining that the output characteristics of the chip to be tested have not been adjusted, the target adjustment solution corresponding to the chip is determined among a plurality of adjustment solutions in a targeted manner according to the output performance of the chip to be tested. The E-fuse in the chip to be tested is subjected to blowing treatment according to the target adjustment solution, so as to adjust the output characteristics of the chip to be tested.
    Type: Application
    Filed: August 31, 2021
    Publication date: May 5, 2022
    Applicant: CHANGXIN MEMORY TECHNOLOGIES, INC.
    Inventors: Liang CHEN, Yangyang YIN, Bohong CHEN
  • Aromatherapy lamp shade
    Patent number: D1073175
    Type: Grant
    Filed: November 27, 2024
    Date of Patent: April 29, 2025
    Inventor: Bohong Chen