Patents by Inventor Bohumil Dymacek

Bohumil Dymacek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SIPONIMOD SALTS AND COCRYSTALS
    Publication number: 20240010616
    Abstract: The presented invention relates to solid forms of Siponimod adipic acid salt and cocrystal.
    Type: Application
    Filed: September 24, 2021
    Publication date: January 11, 2024
    Inventors: Bohumil DYMACEK, Jiri PARTL, Nicolas TESSON, Montserrat TRILLA CASTANO
  • IMPROVED PROCESS FOR PREPARATION OF APALUTAMIDE
    Publication number: 20230312507
    Abstract: The presented invention relates to a process for preparation of Apalutamide, compound (1) (Formula 1) or a salt or a solvate thereof: The presented invention further relates to solid forms of Apalutamide, solvates of Apalutamide and to processes for preparation thereof. The presented invention also relates to solid forms of intermediates used in the process for preparing Compound (1).
    Type: Application
    Filed: September 3, 2021
    Publication date: October 5, 2023
    Inventors: Ondrej HYLSE, David CHALUPA, Bohumil DYMACEK, Marian BUCHLOVIC
  • Pharmaceutical composition comprising sacubitril and valsartan
    Patent number: 10588892
    Abstract: The present invention relates to a pharmaceutical composition comprising a physical mixture of sacubitril sodium and valsartan disodium, wherein the X-ray powder diffraction pattern of valsartan disodium comprises characteristic peaks at the following 2 theta (±0.2) angles: 4.70°, 9.29°, 22.34°, measured using a Cu K? radiation. The invention further relates to the use of said pharmaceutical composition as medicament in the treatment of heart failure.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: March 17, 2020
    Assignee: SYNTHON B.V.
    Inventors: Bohumil Dymacek, Marta Vivancos Martinez, Luis Nogueiras Nieto, Lisardo Alvarez Fernandez, Rohit Kumar, Jose Velada Calzada, Petr Mitas
  • PHARMACEUTICAL COMPOSITION COMPRISING SACUBITRIL AND VALSARTAN
    Publication number: 20190030000
    Abstract: The present invention relates to a pharmaceutical composition comprising a physical mixture of sacubitril sodium and valsartan disodium, wherein the X-ray powder diffraction pattern of valsartan disodium comprises characteristic peaks at the following 2 theta (±0.2) angles: 4.70°, 9.29°, 22.34°, measured using a Cu K? radiation. The invention further relates to the use of said pharmaceutical composition as medicament in the treatment of heart failure.
    Type: Application
    Filed: July 26, 2018
    Publication date: January 31, 2019
    Inventors: Bohumil DYMACEK, Marta VIVANCOS MARTINEZ, Luis NOGUEIRAS NIETO, Lisardo ALVAREZ FERNANDEZ, Rohit KUMAR, Jose VELADA CALZADA, Petr MITAS
  • Process for making duloxetine and related compounds
    Patent number: 7928250
    Abstract: A compound of formula 10 is useful in making duloxetine.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: April 19, 2011
    Assignee: Synthon BV
    Inventors: Karel Pospisilik, Bohumil Dymacek
  • Process for making duloxetine and related compounds
    Publication number: 20080171887
    Abstract: A compound of formula 10 is useful in making duloxetine.
    Type: Application
    Filed: December 20, 2007
    Publication date: July 17, 2008
    Inventors: Karel Pospisilik, Bohumil Dymacek