Patents by Inventor Boi Bryant Quach

Boi Bryant Quach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR IDENTIFICATION OF ANTIGEN SPECIFIC T CELLS
    Publication number: 20230194504
    Abstract: Disclosed herein are antigenic peptide-MHC complexes, termed comPACT polypeptides and comPACT polynucleotides, and methods of producing such complexes. Also discloses herein are methods of producing libraries of comPACT polynucleotides and polypeptides, and their exemplary use in capturing cancer neoepitope-reactive T cells with high accuracy. Dual particle detection approaches for detection of neoantigen specific T cells with improved sensitivity and specificity are provided. Signal to noise ratio analysis of isolated T cells for detection of neoantigen-specific T cells with improved T cells is also provided.
    Type: Application
    Filed: October 28, 2022
    Publication date: June 22, 2023
    Applicant: PACT PHARMA, INC.
    Inventors: Songming Peng, Boi Bryant Quach, Duo An, Xiaoyan Robert Bao, Alex Franzusoff, Barbara Sennino, Olivier Dalmas, Stefanie Mandl-Cashman
  • Compositions and methods for identification of antigen specific T cells
    Patent number: 11513113
    Abstract: Disclosed herein are antigenic peptide-MHC complexes, termed comPACT polypeptides and comPACT polynucleotides, and methods of producing such complexes. Also discloses herein are methods of producing libraries of comPACT polynucleotides and polypeptides, and their exemplary use in capturing cancer neoepitope-reactive T cells with high accuracy. Dual particle detection approaches for detection of neoantigen specific T cells with improved sensitivity and specificity are provided. Signal to noise ratio analysis of isolated T cells for detection of neoantigen-specific T cells with improved T cells is also provided.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: November 29, 2022
    Assignee: PACT PHARMA, INC.
    Inventors: Songming Peng, Boi Bryant Quach, Duo An, Xiaoyan Robert Bao, Alex Franzusoff, Barbara Sennino, Olivier Dalmas, Stefanie Mandl-Cashman
  • COMPOSITIONS AND METHODS FOR IDENTIFICATION OF ANTIGEN SPECIFIC T CELLS
    Publication number: 20200256849
    Abstract: Disclosed herein are antigenic peptide-MHC complexes, termed comPACT polypeptides and comPACT polynucleotides, and methods of producing such complexes. Also discloses herein are methods of producing libraries of comPACT polynucleotides and polypeptides, and their exemplary use in capturing cancer neoepitope-reactive T cells with high accuracy. Dual particle detection approaches for detection of neoantigen specific T cells with improved sensitivity and specificity are provided. Signal to noise ratio analysis of isolated T cells for detection of neoantigen-specific T cells with improved T cells is also provided.
    Type: Application
    Filed: February 12, 2020
    Publication date: August 13, 2020
    Applicant: PACT Pharma, Inc.
    Inventors: Songming Peng, Boi Bryant Quach, Duo An, Xiaoyan Robert Bao, Alexis Franzusoff, Barbara Sennino, Olivier Dalmas, Stefanie Mandl-Cashman