Patents by Inventor Bolei CAI

Bolei CAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular self-assembled nanoparticles and preparation method and application thereof
    Patent number: 12685783
    Abstract: Molecular self-assembled nanoparticles and a preparation method and application thereof are provided in the present application, relating to the technical field of precise treatment of arthritis. The molecular self-assembled nanoparticles include a neutrophil membrane and aspirin-functionalized polyethylene glycol (PEG) nanoparticles, where the neutrophil membrane is coated on a surface of the aspirin-functionalized PEG nanoparticles, and a mass ratio of the neutrophil membrane to the aspirin-functionalized PEG nanoparticles is 1:8.
    Type: Grant
    Filed: August 3, 2023
    Date of Patent: July 21, 2026
    Assignee: AIR FORCE MEDICAL UNIVERSITY
    Inventors: Bolei Cai, Liang Kong, Feng Cao, Fuwei Liu, Le Wang, Yunpeng Li, Taiqiang Dai, Han Bao
  • METHOD FOR NANOMORPHOLOGICAL MODIFICATION OF POLYETHER ETHER KETONE SURFACE BY HOT PRESSING, MODIFIED POLYETHER ETHER KETONE MATERIAL AND APPLICATION THEREOF
    Publication number: 20240270904
    Abstract: Disclosed is a method for nanomorphological modification of polyether ether ketone (PEEK) surface by hot pressing, relating to the technical field of biomaterials. The method includes the following steps: S1, preparing SiO2 nanospheres; S2, uniformly laying the SiO2 nanospheres prepared in the S1 on a surface of a PEEK material; S3, heating the surface of the PEEK material to a temperature higher than a glass phase transition temperature, then carrying out hot pressing to embed the SiO2 nanospheres into the surface of the PEEK material, and naturally cooling at room temperature after the hot pressing; S4, after cooling, using NaOH solution to corrode and remove the SiO2 nanospheres on the surface of the PEEK material after hot pressing in S3 to form a structure with nanoconcaves, then obtaining a hot-pressed modified PEEK material.
    Type: Application
    Filed: January 12, 2024
    Publication date: August 15, 2024
    Inventors: Liang KONG, Fuwei LIU, He XIN, Weiwei WU, Gandong ZHOU, Xuelian JIA, Yunpeng LI, Bolei CAI, Lei TIAN, Mingchao DING, Ye GAO, Yan HOU, Qianxin LV
  • MOLECULAR SELF-ASSEMBLED NANOPARTICLES AND PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20240207437
    Abstract: Molecular self-assembled nanoparticles and a preparation method and application thereof are provided in the present application, relating to the technical field of precise treatment of arthritis. The molecular self-assembled nanoparticles include a neutrophil membrane and aspirin-functionalized polyethylene glycol (PEG) nanoparticles, where the neutrophil membrane is coated on a surface of the aspirin-functionalized PEG nanoparticles, and a mass ratio of the neutrophil membrane to the aspirin-functionalized PEG nanoparticles is 1:8.
    Type: Application
    Filed: August 3, 2023
    Publication date: June 27, 2024
    Inventors: Bolei CAI, Liang KONG, Feng CAO, Fuwei LIU, Le WANG, Yunpeng LI, Taiqiang DAI, Han BAO