Patents by Inventor Bolleddula Jayaprakasam

Bolleddula Jayaprakasam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF OBESITY, INSULIN RELATED DISEASES AND HYPERCHOLESTEROLEMIA
    Publication number: 20120283203
    Abstract: A process of enhancing insulin excretion in a subject includes administering to the subject a polyphenol active ingredient. The polyphenol active ingredient is a purified cyanidin-3-glycoside alone or purified cyanidin alone. The pharmaceutically acceptable carrier is administered with the polyphenol active ingredient.
    Type: Application
    Filed: April 30, 2012
    Publication date: November 8, 2012
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia
    Patent number: 8198249
    Abstract: A process of enhancing insulin excretion in a subject includes administering to the subject a polyphenol active ingredient. The polyphenol active ingredient is a purified cyanidin-3-glycoside alone or purified cyanidin alone. The pharmaceutically acceptable carrier is administered with the polyphenol active ingredient.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: June 12, 2012
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF OBESITY, INSULIN RELATED DISEASES AND HYPERCHOLESTEROLEMIA
    Publication number: 20110003762
    Abstract: A process of enhancing insulin excretion in a subject includes administering to the subject a polyphenol active ingredient. The polyphenol active ingredient is a purified cyanidin-3-glycoside alone or purified cyanidin alone. The pharmaceutically acceptable carrier is administered with the polyphenol active ingredient.
    Type: Application
    Filed: May 4, 2010
    Publication date: January 6, 2011
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia
    Patent number: 7772195
    Abstract: A method for the treatment of obesity, diabetes, high cholesterol and related diseases including hyperglycemia, lipid disorders, hyperglyceridemia, dyslipidemia and atherosclerosis in mammals using anthocyanins, anthocyanidins, ursolic acid and/or betulinic acid is described. Compositions adapted for these treatments are also described.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: August 10, 2010
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, Lawrence K. Olson, Robert E. Schutzki
  • Insulin secretion by anthocyanins and anthocyanidins
    Patent number: 7737121
    Abstract: A method for stimulating insulin secretion by anthocyanidins and anthocyanins is described. The secretion can be in vivo in mammals, including humans, or in vitro.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: June 15, 2010
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam, L. Karl Olson, Shaiju K. Vareed
  • Withanamide and withanolide compositions and method of use thereof
    Patent number: 7282593
    Abstract: Novel isolated and purified withanamides and withanolides are described. In particular, compounds from Withania somnifera fruit are the preferred source of the withanamides and withanolides, although they can be from other plant sources. In addition to their use as powerful antioxidants, the withanamides and withanolides can be useful for the treatment of depression, Alzheimer's Disease, obesity and migraine headaches.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: October 16, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7270836
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 18, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7264831
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 4, 2007
    Assignee: Board of Trustees of Michigan State Univeristy
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7264833
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 4, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7264832
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: September 4, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7211277
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: May 1, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7208182
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: April 24, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7195784
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: March 27, 2007
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Patent number: 7141253
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Grant
    Filed: July 8, 2004
    Date of Patent: November 28, 2006
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Publication number: 20060251740
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Application
    Filed: April 19, 2006
    Publication date: November 9, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Publication number: 20060246160
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Application
    Filed: April 19, 2006
    Publication date: November 2, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Publication number: 20060247182
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Application
    Filed: April 19, 2006
    Publication date: November 2, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Publication number: 20060246158
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source-of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Application
    Filed: April 19, 2006
    Publication date: November 2, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-2 inhibitory withanolide compositions and method
    Publication number: 20060246159
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source-of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Application
    Filed: April 19, 2006
    Publication date: November 2, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan Nair, Bolleddula Jayaprakasam
  • Cyclooxygenase-3 inhibitory withanolide compositions and method
    Publication number: 20060188592
    Abstract: Cyclooxygenase-2 enzyme inhibiting withanolides are described. In particular, compounds from Withania somnifera are the preferred source of the withanolides, although they can be from other plant sources. The COX-2 inhibition is selective over COX-1.
    Type: Application
    Filed: April 19, 2006
    Publication date: August 24, 2006
    Applicant: Board of Trustees of Michigan State University
    Inventors: Muraleedharan Nair, Bolleddula Jayaprakasam