Abstract: The present invention discloses a gene sequencing data compression preprocessing, compression and decompression method, a system, and a computer-readable medium. The preprocessing method implementation steps include: obtaining reference genome data; obtaining a mapping relationship between a short string K-mer and a prediction character c to obtain a prediction data model P1 containing any short string K-mer in the positive strand and negative strand of a reference genome and the prediction character c in a corresponding adjacent bit. The compression and decompression methods relate to performing compression/decompression on the basis of the prediction data model P1. The system is a computer system including a program for executing the previous method. The computer-readable medium includes a computer program for executing the previous method.

Abstract: This invention relates to a gene sequencing quality line data compression pre-processing and decompression and restoration method, and a system, wherein the basic principle of the gene sequencing quality line data compression pre-processing and decompression and restoration is to extract several columns from an inputted quality line document or data block to act as index columns, and then perform rearrangement on all quality line data, all quality lines having a same index column being one group and being arranged together according to their relative positions in the original data block. Since quality line data having a same index column is usually more similar, the data reorganization means can arrange similar gene sequencing data together, so as to increase local similarity of the data.

Abstract: The invention discloses a gene sequencing data compression method and decompression method, a system, and a computer-readable medium. The compression method includes: comparing a read sequence R with a reference genome to obtain an equal-length gene character sequence CS; coding the read sequence R and the equal-length gene character sequence CS, performing reversible computing by means of a reversible function, compressing a most approximate position p of the read sequence R in the reference genome and the reversible computing result that serve as two data streams, and outputting the compressed data streams. The data decompression method is reverse processing of the compression method. By means of the present invention, the compression ratio can be further decreased, the compression/decompression time of an algorithm is shorter while a better compression ratio is obtained. The present invention is compatible with algorithms for making comparisons between read sequences and reference genomes.

Abstract: The present invention discloses a gene sequencing data compression preprocessing, compression and decompression method, a system, and a computer-readable medium. The preprocessing method implementation steps include: obtaining reference genome data; obtaining a mapping relationship between a short string K-mer and a prediction character c to obtain a prediction data model P1 containing any short string K-mer in the positive strand and negative strand of a reference genome and the prediction character c in a corresponding adjacent bit. The compression and decompression methods relate to performing compression/decompression on the basis of the prediction data model P1. The system is a computer system including a program for executing the previous method. The computer-readable medium includes a computer program for executing the previous method.