Patents by Inventor Bong-hee Lee

Bong-hee Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9662347
    Abstract: The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the mononuclear phagocyte system, to an AGE-albumin synthesis inhibitor, and to a pharmaceutical composition comprising the AGE-albumin synthesis inhibitor for preventing or treating degenerative disease and autoimmune disease. The AGE-albumin of the present invention is synthesized and secreted in human microglia or human macrophages in an Alzheimer's model, stroke model, Parkinson's disease model and rheumatoid arthritis model. The AGE-albumin synthesis and secretion are caused by oxidative stress. The expression of RAGE increases in first-order human neurons or cartilage cells to which AGE-albumin is administered, whereupon a MAPK signaling pathway is activated and the expression of Bax increases to induce an increase in calcium in mitochondria, thus finally inducing cell death.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: May 30, 2017
    Assignee: Gachon University of Industry-Academic Cooperation Foundation
    Inventors: Bong Hee Lee, Kyung Hee Byun
  • Publication number: 20160327893
    Abstract: A belt type fixing apparatus comprises: a fixing roller; a fixing belt which is installed to be opposite to the fixing roller; a nip forming member which is installed inside the fixing belt and supports the fixing belt so that the fixing belt can contact the fixing roller to form a fixing nip; a pair of sliding members which are installed to support both ends of the fixing belt and are rotated by the fixing belt; a pair of flange members which rotatably support the pair of sliding members; and a heat source which is installed inside the fixing belt and generates heat, wherein the rotation center of the pair of sliding members is located upstream in the transportation direction of printed matter compared to the rotation center of the fixing roller.
    Type: Application
    Filed: December 23, 2014
    Publication date: November 10, 2016
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jun-tae KIM, Seung-jun LEE, Dong-woo LEE, Dong-jin SEOL, Soo-hwan BAE, Bong-hee LEE
  • Patent number: 9465339
    Abstract: A fixing device including a lubricant supply unit is provided. The lubricant supply unit supplies a lubricant between a fixing belt and a nip forming member and includes a lubricant storage member and an impregnation member. The lubricant storage member stores the lubricant, and the impregnation member impregnates the lubricant discharged from the lubricant storage member and supplies the lubricant to an inner surface of the fixing belt. The lubricant stored in the lubricant storage member includes base oil and a thickener, and a weight of the thickener is equal to or less than 20% with respect to a weight of the lubricant.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: October 11, 2016
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Seung-jun Lee, Dong-jin Seol, Bong-hee Lee
  • Patent number: 9371387
    Abstract: Disclosed is a pharmaceutical composition for the prevention or treatment of ischemic heart diseases, comprising as an active ingredient an inhibitor which acts to restrain mononuclear phagocyte system cells from synthesizing or releasing AGE-albumin, which induces the apoptosis of cardiomyocytes upon the onset of the ischemic heart disease. Also, a method is provided for screening an inhibitor against the AGE-albumin synthesis or release of mononuclear phagocyte system cells. Inhibitory or suppressive of AGE-albumin-induced cell death, the pharmaceutical composition comprising as an active ingredient an inhibitor against the AGE-albumin synthesis or release of mononuclear phagocyte system cells can be applied to the prevention or treatment of a wide spectrum of ischemic heart diseases including myocardial infarction.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: June 21, 2016
    Assignee: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Bong Hee Lee, Kyung Hee Byun
  • Patent number: 9234900
    Abstract: The present invention relates to a method for diagnosing glioma by comparing the protein location of an individual to be diagnosed with the normal control nerve cells. More particularly, the present invention relates to a method for diagnosing glioma including determining that an individual has glioma when the expression level of GFR?4 in the endoplasmic reticulum is higher than that in the plasma membrane, and a method for screening a therapeutic agent for glioma. In the diagnostic method of the present invention, the protein expression levels in particular subcellular locations are compared, thereby accurately diagnosing glioma, diagnosing progression of glioma, and predicting prognosis after glioma surgery.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: January 12, 2016
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Ki Young Lee, Bong Hee Lee, Kyung Hee Byun, Sun Ha Paek
  • Publication number: 20150198919
    Abstract: A fixing device including a lubricant supply unit is provided. The lubricant supply unit supplies a lubricant between a fixing belt and a nip forming member and includes a lubricant storage member and an impregnation member. The lubricant storage member stores the lubricant, and the impregnation member impregnates the lubricant discharged from the lubricant storage member and supplies the lubricant to an inner surface of the fixing belt. The lubricant stored in the lubricant storage member includes base oil and a thickener, and a weight of the thickener is equal to or less than 20% with respect to a weight of the lubricant.
    Type: Application
    Filed: December 15, 2014
    Publication date: July 16, 2015
    Inventors: Seung-jun LEE, Dong-jin SEOL, Bong-hee LEE
  • Publication number: 20140234343
    Abstract: Disclosed is a pharmaceutical composition for the prevention or treatment of ischemic heart diseases, comprising as an active ingredient an inhibitor which acts to restrain mononuclear phagocyte system cells from synthesizing or releasing AGE-albumin, which induces the apoptosis of cardiomyocytes upon the onset of the ischemic heart disease. Also, a method is provided for screening an inhibitor against the AGE-albumin synthesis or release of mononuclear phagocyte system cells. Inhibitory or suppressive of AGE-albumin-induced cell death, the pharmaceutical composition comprising as an active ingredient an inhibitor against the AGE-albumin synthesis or release of mononuclear phagocyte system cells can be applied to the prevention or treatment of a wide spectrum of ischemic heart diseases including myocardial infarction.
    Type: Application
    Filed: November 12, 2012
    Publication date: August 21, 2014
    Inventors: Bong Hee Lee, Kyung Hee Byun
  • Patent number: 8805255
    Abstract: A fusing apparatus to fuse a toner image transferred to a printing medium by applying heat and pressure. The fusing apparatus includes a separation member that is rotatably mounted on a rotation axis to separate the printing medium from one of a heating roller and a pressing roller. The separation member includes a hollow portion into which the rotation axis is inserted, and a separation portion that contacts an outer circumference of the heating roller. The separation member is installed so as to be pitched around the rotation axis and a pitching axis having an inclination angle within a range of ±10° with respect to a line that connects a contact point between the separation portion and the outer circumference of the roller from which the printing medium is to be separated and a center of the roller from which the printing medium is to be separated.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: August 12, 2014
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jin-seok Lee, Bong-hee Lee, Sang-uk Jeon, Dong-kyun Kim
  • Patent number: 8750737
    Abstract: An image forming apparatus includes a heat roller heated to a preset temperature; a pressure roller for having conductivity and forming a nip by pressure-contacting with the heat roller; a power supply unit to apply a bias voltage to the pressure roller; and a controller to, when a printing paper enters the nip, control the power supply unit to apply the bias voltage to the pressure roller. When a time interval is longer than a preset time, the controller can control the power supply unit not to apply the bias voltage when the printing paper is not placed in the nip, and when the time interval is shorter than the preset time, the controller can control the power supply unit to apply the bias voltage when the printing paper is not placed in the nip.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: June 10, 2014
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jin-seok Lee, Bong-hee Lee, Sang-uk Jeon, Dong-kyun Kim
  • Publication number: 20140106376
    Abstract: The present invention relates to a method for diagnosing glioma by comparing the protein location of an individual to be diagnosed with the normal control nerve cells. More particularly, the present invention relates to a method for diagnosing glioma including determining that an individual has glioma when the expression level of GFR?4 in the endoplasmic reticulum is higher than that in the plasma membrane, and a method for screening a therapeutic agent for glioma. In the diagnostic method of the present invention, the protein expression levels in particular subcellular locations are compared, thereby accurately diagnosing glioma, diagnosing progression of glioma, and predicting prognosis after glioma surgery.
    Type: Application
    Filed: October 21, 2013
    Publication date: April 17, 2014
    Applicant: Ajou University Industry-Academic Cooperation Foundation
    Inventors: Ki Young LEE, Bong Hee LEE, Kyung Hee BYUN, Sun Ha PAEK
  • Publication number: 20130131006
    Abstract: The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the mononuclear phagocyte system, to an AGE-albumin synthesis inhibitor, and to a pharmaceutical composition comprising the AGE-albumin synthesis inhibitor for preventing or treating degenerative disease and autoimmune disease. The AGE-albumin of the present invention is synthesized and secreted in human microglia or human macrophages in an Alzheimer's model, stroke model, Parkinson's disease model and rheumatoid arthritis model. The AGE-albumin synthesis and secretion are caused by oxidative stress. The expression of RAGE increases in first-order human neurons or cartilage cells to which AGE-albumin is administered, whereupon a MAPK signaling pathway is activated and the expression of Bax increases to induce an increase in calcium in mitochondria, thus finally inducing cell death.
    Type: Application
    Filed: April 28, 2011
    Publication date: May 23, 2013
    Applicant: Gachon University of Industry-Academic Cooperation Foundation
    Inventors: Bong Hee Lee, Kyung Hee Byun
  • Publication number: 20120207524
    Abstract: A fusing apparatus to fuse a toner image transferred to a printing medium by applying heat and pressure. The fusing apparatus includes a separation member that is rotatably mounted on a rotation axis to separate the printing medium from one of a heating roller and a pressing roller. The separation member includes a hollow portion into which the rotation axis is inserted, and a separation portion that contacts an outer circumference of the heating roller. The separation member is installed so as to be pitched around the rotation axis and a pitching axis having an inclination angle within a range of ±10° with respect to a line that connects a contact point between the separation portion and the outer circumference of the roller from which the printing medium is to be separated and a center of the roller from which the printing medium is to be separated.
    Type: Application
    Filed: October 6, 2011
    Publication date: August 16, 2012
    Applicant: SAMSUNG ELECTRONICS CO., LTD
    Inventors: Jin-seok Lee, Bong-hee Lee, Sang-uk Jeon, Dong-kyun Kim
  • Publication number: 20120063798
    Abstract: An image forming apparatus includes a heat roller heated to a preset temperature; a pressure roller for having conductivity and forming a nip by pressure-contacting with the heat roller; a power supply unit to apply a bias voltage to the pressure roller; and a controller to, when a printing paper enters the nip, control the power supply unit to apply the bias voltage to the pressure roller. When a time interval is longer than a preset time, the controller can control the power supply unit not to apply the bias voltage when the printing paper is not placed in the nip, and when the time interval is shorter than the preset time, the controller can control the power supply unit to apply the bias voltage when the printing paper is not placed in the nip.
    Type: Application
    Filed: January 18, 2011
    Publication date: March 15, 2012
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Jin-seok Lee, Bong-hee Lee, Sang-uk Jeon, Dong-kyun Kim
  • Patent number: 7831188
    Abstract: An image forming apparatus and a fusing unit thereof. The image forming apparatus includes a photosensitive body on which to form an electrostatic latent image, an exposure device to irradiate light to the photosensitive body to form the electrostatic latent image, a developer adhering device to adhere a developer to the photosensitive body on which the electrostatic latent image has been formed to form a visible image, a transfer device to transfer the visible image formed on the photosensitive body onto a printing medium, and a fusing unit to fuse the visible image transferred onto the printing medium to the printing medium.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: November 9, 2010
    Assignee: Samsung Electronics Co., Ltd
    Inventor: Bong Hee Lee
  • Publication number: 20100098442
    Abstract: Disclosed is a waste developer collecting unit of an image forming apparatus that can include a casing configured to store waste developer, an auger rotatably disposed inside the casing and configured to move the waste developer around inside the casing, a detection unit configured to detect a load applied to the auger, the applied load being in corresponding relationship with an amount of waste developer stored in the casing, and a control unit configured to determine whether the amount of waste developer in the casing has reached a reference amount based on the detection result produced by the detection unit.
    Type: Application
    Filed: September 17, 2009
    Publication date: April 22, 2010
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Bong-Hee LEE
  • Patent number: 7547015
    Abstract: An image forming apparatus has an image forming part forming an image on paper, and a housing accommodating the image forming part and having a paper stack part stacking paper discharged from the image forming part, and the image forming apparatus includes an accommodating part formed in an edge of the paper stack part and extending in a paper discharge direction; a base plate mounted in the accommodating part to be slidable in the paper discharge direction and a reverse direction opposite to the paper discharge direction; and a stopper hinge-coupled to the base plate to be tiltable among a stand up position where the stopper blocks paper discharged from the image forming part, a rear folding position where the stopper is folded onto the base plate and is at least partially accommodated in the paper stack part, and a front folding position where the stopper is folded in the paper discharge direction.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: June 16, 2009
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Bong-hee Lee, Ho-min Lim
  • Patent number: 7505713
    Abstract: A rollers separating unit which controls a distance between a heating roller and a pressurizing roller of a fixing unit by an opening/closing of a side cover. The rollers separating unit includes an elastic support member rotatably hinge-coupled to one side of a housing of a fixing unit, to elastically support a roller installed at an outer portion of a main body between a pair of rollers so that the pair of rollers pressurize each other, a first lever rotatably hinge-coupled to one end of the elastic support member, to rotate the elastic support member at a first predetermined angle so that the pair of rollers are separated from each other, and a side cover rotatably hinge-coupled to one side of the main body, to increase a distance between the pair of rollers by operating the first lever.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: March 17, 2009
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Bong-hee Lee, Ho-min Lim
  • Patent number: 7466934
    Abstract: A method and apparatus to control the fusing temperature of an image forming apparatus. This method of controlling the fusing temperature of an image forming apparatus having a fan to exhaust the internal air to the outside includes counting the accumulated number of sheets of paper printed in response to print commands, lowering a set point of the fusing temperature and controlling the fan to increase the amount of air to be exhausted when the accumulated number of sheets of printed paper is greater than a predetermined value. According to the method, without installing an additional temperature sensor inside the image forming apparatus, the temperature therein can be presumed and controlled by controlling the fusing temperature of the fusing roller and a fan flow rate to lower the temperature of the paper, and consequently, preventing the formation of creases in the paper.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: December 16, 2008
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Seok-heon Chae, Bong-hee Lee
  • Publication number: 20080286018
    Abstract: An image forming apparatus and a fusing unit thereof. The image forming apparatus includes a photosensitive body on which to form an electrostatic latent image, an exposure device to irradiate light to the photosensitive body to form the electrostatic latent image, a developer adhering device to adhere a developer to the photosensitive body on which the electrostatic latent image has been formed to form a visible image, a transfer device to transfer the visible image formed on the photosensitive body onto a printing medium, and a fusing unit to fuse the visible image transferred onto the printing medium to the printing medium.
    Type: Application
    Filed: April 18, 2008
    Publication date: November 20, 2008
    Applicant: Samsung Electronics Co., Ltd
    Inventor: Bong Hee Lee
  • Patent number: 7346294
    Abstract: An image forming apparatus includes a main body frame, an image forming unit disposed inside of the main body frame to form an image, a door unit disposed in such a manner to make a conjoin rotation to thereby approach to a paper transfer path disposed inside of the main body frame, a roller assembly disposed on the paper transfer path, and an opening and closing coupling unit to couple the door unit with the roller assembly, wherein the roller assembly is opened/closed when the door unit is opened/closed.
    Type: Grant
    Filed: October 13, 2005
    Date of Patent: March 18, 2008
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Bong-hee Lee