Patents by Inventor Bonghee SOHN

Bonghee SOHN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric Spider Silk Polypeptides and Fibers and Uses Thereof
    Publication number: 20150322121
    Abstract: Transgenic silkworms comprising at least one nucleic acid encoding a chimeric silk polypeptide comprising one or more spider silk elasticity and strength motifs are disclosed. Expression cassettes comprising nucleic acids encoding a variety of chimeric spider silk polypeptides (Spider 2, Spider 4, Spider 6, Spider 8) are also disclosed. A piggyBac vector system is used to incorporate nucleic acids encoding chimeric spider silk polypeptides into the mutant silkworms to generate stable transgenic silkworms. Chimeric silk fibers having improved tensile strength and elasticity characteristics compared to native silkworm silk fibers are also provided. The transgenic silkworms greatly facilitate the commercial production of chimeric silk fibers suitable for use in a wide variety of medical and industrial applications.
    Type: Application
    Filed: June 30, 2015
    Publication date: November 12, 2015
    Inventors: Malcolm James FRASER, Randy LEWIS, Don JARVIS, Kimberly THOMPSON, Joseph HULL, Yun-Gen MAO, Florence TEULE, Bonghee SOHN, Youngsoo KIM
  • Transgenic Silkworms Capable of Producing Chimeric Spider Silk Polypeptides and Fibers
    Publication number: 20150322122
    Abstract: Transgenic silkworms comprising at least one nucleic acid encoding a chimeric silk polypeptide comprising one or more spider silk elasticity and strength motifs are disclosed. Expression cassettes comprising nucleic acids encoding a variety of chimeric spider silk polypeptides (Spider 2, Spider 4, Spider 6, Spider 8) are also disclosed. A piggyBac vector system is used to incorporate nucleic acids encoding chimeric spider silk polypeptides into the mutant silkworms to generate stable transgenic silkworms. Chimeric silk fibers having improved tensile strength and elasticity characteristics compared to native silkworm silk fibers are also provided. The transgenic silkworms greatly facilitate the commercial production of chimeric silk fibers suitable for use in a wide variety of medical and industrial applications.
    Type: Application
    Filed: June 30, 2015
    Publication date: November 12, 2015
    Inventors: Malcolm James FRASER, Randy LEWIS, Don JARVIS, Kimberly THOMPSON, Joseph HULL, Yun-Gen MAO, Florence TEULE, Bonghee SOHN, Youngsoo KIM
  • CHIMERIC SPIDER SILK AND USES THEREOF
    Publication number: 20130212718
    Abstract: Transgenic silkworms comprising at least one nucleic acid encoding a chimeric silk polypeptide comprising one or more spider silk elasticity and strength motifs are disclosed. Expression cassettes comprising nucleic acids encoding a variety of chimeric spider silk polypeptides (Spider 2, Spider 4, Spider 6, Spider 8) are also disclosed. A piggyBac vector system is used to incorporate nucleic acids encoding chimeric spider silk polypeptides into the mutant silkworms to generate stable transgenic silkworms. Chimeric silk fibers having improved tensile strength and elasticity characteristics compared to native silkworm silk fibers are also provided. The transgenic silkworms greatly facilitate the commercial production of chimeric silk fibers suitable for use in a wide variety of medical and industrial applications.
    Type: Application
    Filed: March 28, 2013
    Publication date: August 15, 2013
    Inventors: Malcolm James FRASER, Randy LEWIS, Don JARVIS, Kimberly THOMPSON, Joseph HULL, Yun-Gen MIAO, Florence TEULE, Bonghee SOHN, Youngsoo KIM