Patents by Inventor Bonnie Blazer-Yost

Bonnie Blazer-Yost has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of TRPV4 antagonists to ameliorate hydrocephalus and related materials and methods
    Patent number: 11318140
    Abstract: The present disclosure provides uses of TRPV4 antagonists in the treatment or prevention of hydrocephalus symptoms, also known as hydrocephaly, including hydrocephalus as a result of any structural defect, any metabolic defect, any injury (direct force to the head, indirect force to the head, shock waves, pressure changes, etc.), any insult (microbial, chemical, toxins, allergic reactions or other inflammatory process, or other pathology, e.g. cancer, benign tumor, etc.). Related materials and methods are also provided herein.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: May 3, 2022
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Vincent Gattone, Bonnie Blazer-Yost
  • PPAR GAMMA MODULATORS FOR TREATING CYSTIC DISEASES
    Publication number: 20200121665
    Abstract: Compositions and methods are described herein for the treatment of cystic diseases using PPAR? modulators. In particular, compositions and methods are described herein for the treatment of cystic diseases using low doses of PPAR? modulators.
    Type: Application
    Filed: September 24, 2019
    Publication date: April 23, 2020
    Inventor: Bonnie Blazer-Yost
  • USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS
    Publication number: 20190262350
    Abstract: The present disclosure provides uses of TRPV4 antagonists in the treatment or prevention of hydrocephalus symptoms, also known as hydrocephaly, including hydrocephalus as a result of any structural defect, any metabolic defect, any injury (direct force to the head, indirect force to the head, shock waves, pressure changes, etc.), any insult (microbial, chemical, toxins, allergic reactions or other inflammatory process, or other pathology, e.g. cancer, benign tumor, etc.). Related materials and methods are also provided herein.
    Type: Application
    Filed: May 14, 2019
    Publication date: August 29, 2019
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Vincent Gattone, Bonnie Blazer-Yost
  • Use of TRPV4 antagonists to ameliorate hydrocephalus and related materials and methods
    Patent number: 10335414
    Abstract: The present invention provides uses of TRPV4 antagonists in the treatment or prevention of hydrocephalus symptoms, also known as hydrocephaly, including hydrocephalus as a result of any structural defect, any metabolic defect, any injury (direct force to the head, indirect force to the head, shock waves, pressure changes, etc.), any insult (microbial, chemical, toxins, allergic reactions or other inflammatory process, or other pathology, eg. cancer, benign tumor, etc.). Related materials and methods are also provided herein.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: July 2, 2019
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Vincent Gattone, Bonnie Blazer-Yost
  • Treatment of cystic diseases
    Patent number: 9579335
    Abstract: The invention described herein pertains to the treatment of cystic diseases. More particularly, the invention described herein relates to methods for treating cystic disease using one or more lysophosphatidic acid antagonists, TMEM16a inhibitors, and/or peroxisome proliferator-activated receptor modulators.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: February 28, 2017
    Assignee: Indiana University Research and Technology Corporation
    Inventor: Bonnie Blazer-Yost
  • PPAR GAMMA MODULATORS FOR TREATING CYSTIC DISEASES
    Publication number: 20160128994
    Abstract: Compositions and methods are described herein for the treatment of cystic diseases using PPAR? modulators. In particular, compositions and methods are described herein for the treatment of cystic diseases using low doses of PPAR? modulators.
    Type: Application
    Filed: June 6, 2014
    Publication date: May 12, 2016
    Applicant: Indiana University Research & Technology Corporation
    Inventor: Bonnie Blazer-Yost
  • TREATMENT OF CYSTIC DISEASES
    Publication number: 20160000814
    Abstract: The invention described herein pertains to the treatment of cystic diseases. More particularly, the invention described herein relates to methods for treating cystic disease using one or more lysophosphatidic acid antagonists, TMEM16a inhibitors, and/or peroxisome proliferator-activated receptor modulators.
    Type: Application
    Filed: September 14, 2015
    Publication date: January 7, 2016
    Inventor: Bonnie Blazer-Yost
  • Use of TRPV4 Antagonists to Ameliorate Hydrocephalus and Related Materials and Methods
    Publication number: 20150290206
    Abstract: The present invention provides uses of TRPV4 antagonists in the treatment or prevention of hydrocephalus symptoms, also known as hydrocephaly, including hydrocephalus as a result of any structural defect, any metabolic defect, any injury (direct force to the head, indirect force to the head, shock waves, pressure changes, etc.), any insult (microbial, chemical, toxins, allergic reactions or other inflammatory process, or other pathology, eg. cancer, benign tumor, etc.). Related materials and methods are also provided herein.
    Type: Application
    Filed: December 3, 2013
    Publication date: October 15, 2015
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Vincent Gattone, Bonnie Blazer-Yost
  • TREATMENT OF CYSTIC DISEASES
    Publication number: 20120094959
    Abstract: The invention described herein pertains to the treatment of cystic diseases. More particularly, the invention described herein relates to methods for treating cystic disease using one or more lysophosphatidic acid antagonists, TMEM16a inhibitors, and/or peroxisome proliferator-activated receptor modulators.
    Type: Application
    Filed: October 19, 2011
    Publication date: April 19, 2012
    Inventor: Bonnie BLAZER-YOST
  • MEDICAMENTS
    Publication number: 20110224264
    Abstract: Methods of prevention or treatment of renal diseases or conditions associated with abnormal ion flux, in particular autosomal dominant polycystic kidney disease, with a modulator of human peroxisome proliferator activated receptor gamma.
    Type: Application
    Filed: May 13, 2011
    Publication date: September 15, 2011
    Inventors: Kathleen Keating Brown, Bonnie Blazer-Yost
  • TREATMENT OF CYSTIC DISEASE WITH LYSOPHOSPHATIDIC ACID ANTAGONISTS
    Publication number: 20110044973
    Abstract: A method for treating cystic diseases is disclosed herein. The method comprises administering lysophosphatidic acid receptor antagonists.
    Type: Application
    Filed: April 23, 2010
    Publication date: February 24, 2011
    Inventor: Bonnie Blazer-Yost
  • Medicaments
    Publication number: 20100280080
    Abstract: Methods of prevention or treatment of renal diseases or conditions associated with abnormal ion flux, in particular autosomal dominant polycystic kidney disease, with a modulator of human peroxisome proliferator activated receptor gamma.
    Type: Application
    Filed: July 19, 2010
    Publication date: November 4, 2010
    Inventors: Kathleen Keating BROWN, Bonnie BLAZER-YOST
  • Medicaments
    Patent number: 7767682
    Abstract: Methods of prevention or treatment of renal diseases or conditions associated with abnormal ion flux, in particular autosomal dominant polycystic kidney disease, with a modulator of human peroxisome proliferator activated receptor gamma.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: August 3, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: Kathleen Keating Brown, Bonnie Blazer-Yost