Patents by Inventor Boopathy Ramakrishnan

Boopathy Ramakrishnan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY MOLECULE-DRUG CONJUGATES AND USES THEREOF
    Publication number: 20210316004
    Abstract: Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.
    Type: Application
    Filed: April 2, 2021
    Publication date: October 14, 2021
    Inventors: Karthik Viswanathan, Kenneth Douglas Johnson, Obadiah Joseph Plante, James C. Delaney, Tyree J. Koch, Hamid Tissire, Andrew M. Wollacott, Boopathy Ramakrishnan
  • Methods of treating IgA nephropathy by administering an anti-APRIL (a proliferation-inducing ligand) antibody molecule
    Patent number: 11136385
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: October 5, 2021
    Assignee: VISTERRA, INC.
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • ANTIBODY MOLECULE-DRUG CONJUGATES AND USES THEREOF
    Publication number: 20210283220
    Abstract: Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.
    Type: Application
    Filed: January 18, 2018
    Publication date: September 16, 2021
    Inventors: Zachary Shriver, Obadiah Joseph Plante, Kai Li, Karthik Viswanathan, James C. Delaney, Boopathy Ramakrishnan, Andrew M. Wollacott
  • Nucleic acid molecules encoding antibodies to a proliferation-inducing ligand (APRIL)
    Patent number: 10981982
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: April 20, 2021
    Assignee: VISTERRA, INC.
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • Antibody molecules to a proliferation-inducing ligand (APRIL)
    Patent number: 10968270
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: April 6, 2021
    Assignee: VISTERRA, INC.
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • Method of using anti-APRIL (a proliferation-inducing ligand) antibodies to reduce IGA
    Patent number: 10954296
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: March 23, 2021
    Assignee: VISTERRA, INC.
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • Method of using anti-APRIL (a proliferation-inducing ligand) antibodies to reduce IGA
    Patent number: 10919960
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: February 16, 2021
    Assignee: VISTERRA, INC.
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • ANTIBODY MOLECULES TO A PROLIFERATION-INDUCING LIGAND (APRIL)
    Publication number: 20210032324
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Application
    Filed: October 20, 2020
    Publication date: February 4, 2021
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • INTERLEUKIN-2 AGENTS AND USES THEREOF
    Publication number: 20210024601
    Abstract: IL-2 agents that comprise IL-2 variants are disclosed as well as methods, compositions, and uses thereof. The IL-2 agents described herein can be used to treat and/or prevent various disorders and conditions.
    Type: Application
    Filed: July 24, 2020
    Publication date: January 28, 2021
    Inventors: Scott Moore Carlson, Gregory Babcock, Zachary Shriver, Boopathy Ramakrishnan
  • HUMANIZED ANTIBODY MOLECULES TO CD138 AND USES THEREOF
    Publication number: 20200392241
    Abstract: Humanized antibody molecules that specifically bind to CD138 are disclosed. The humanized antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as multiple myeloma.
    Type: Application
    Filed: June 17, 2020
    Publication date: December 17, 2020
    Inventors: Bharat Chaganty, Boopathy Ramakrishnan, Hedy Adari-Hall, Karthik Viswanathan, James R. Myette, Zachary Shriver, Andrew M. Wollacott
  • ANTIBODY MOLECULES TO A PROLIFERATION-INDUCING LIGAND (APRIL)
    Publication number: 20200331995
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 22, 2020
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • ANTIBODY MOLECULES TO A PROLIFERATION-INDUCING LIGAND (APRIL)
    Publication number: 20200317770
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 8, 2020
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • ANTIBODY MOLECULES TO A PROLIFERATION-INDUCING LIGAND (APRIL)
    Publication number: 20200299376
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Application
    Filed: June 10, 2020
    Publication date: September 24, 2020
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • ENGINEERED POLYPEPTIDES AND USES THEREOF
    Publication number: 20200277358
    Abstract: Polypeptides, such as antibody molecules and fusion proteins, comprising an Fc region, are disclosed. The polypeptides can be used to treat, prevent, and/or diagnose disorders.
    Type: Application
    Filed: April 10, 2020
    Publication date: September 3, 2020
    Inventors: Karthik Viswanathan, Boopathy Ramakrishnan, Brian Booth, Kristin Narayan, Andrew M. Wollacott
  • ANTIBODY MOLECULES TO A PROLIFERATION-INDUCING LIGAND (APRIL)
    Publication number: 20190330326
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Application
    Filed: June 28, 2019
    Publication date: October 31, 2019
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • Antibody molecules to a proliferation-inducing ligand (APRIL)
    Patent number: 10385123
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: August 20, 2019
    Assignee: VISTERRA, INC.
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • ANTIBODY MOLECULES TO CD138 AND USES THEREOF
    Publication number: 20190100588
    Abstract: Antibody molecules that specifically bind to CD138 are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as multiple myeloma.
    Type: Application
    Filed: October 2, 2018
    Publication date: April 4, 2019
    Inventors: Bharat Chaganty, Boopathy Ramakrishnan, Hedy Adari-Hall, Karthik Viswanathan, James R. Myette, Zachary Shriver
  • ANTIBODY MOLECULES TO APRIL AND USES THEREOF
    Publication number: 20190092851
    Abstract: Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
    Type: Application
    Filed: December 7, 2018
    Publication date: March 28, 2019
    Inventors: James R. Myette, Zachary Holmes Shriver, Karthik Viswanathan, Andrew M. Wollacott, Hedy Adari-Hall, Boopathy Ramakrishnan, Gregory Babcock
  • ENGINEERED POLYPEPTIDES AND USES THEREOF
    Publication number: 20180037634
    Abstract: Polypeptides, such as antibody molecules and fusion proteins, comprising an Fc region, are disclosed. The polypeptides can be used to treat, prevent, and/or diagnose disorders.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 8, 2018
    Inventors: Karthik Viswanathan, Boopathy Ramakrishnan, Brian Booth, Kristin Narayan, Andrew M. Wollacott
  • HER2-specific monoclonal antibodies and conjugates thereof
    Patent number: 9738726
    Abstract: The identification of Her2-specific monoclonal antibody m860 is described. The m860 antibody was identified from a human naïve phage display Fab library by panning against the extracellular domain of human Her2. M860 binds to cell surface-associated Her2 with an affinity comparable to that of trastuzumab (Herceptin®), but binds to a different epitope. Using site-specific glycan engineering, m860 was conjugated to the small molecule drug auristatin F. The antibody-drug conjugate was stable, bound cell-surface expressed Her2 and exhibited potent cell killing of Her2-positive cancer cells, including trastuzumab-resistant breast cancer cells.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: August 22, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Dimiter S. Dimitrov, Zhongyu Zhu, Pradman K. Qasba, Boopathy Ramakrishnan