Patents by Inventor Bora HWANG

Bora HWANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fc-gamma receptor mutants
    Patent number: 11650209
    Abstract: The present disclosure relates to a polypeptide including an Fc-gamma receptor mutant. The Fc-gamma receptor mutant of the present disclosure is optimized by substituting a part of an amino acid sequence of an Fc-gamma receptor with a different amino acid sequence, so as to provide an excellent selective binding ability to immunoglobulins. Therefore, it can be usefully used for increasing in vivo half-life of drugs, detecting and purifying immunoglobulins, inhibiting organ transplant rejections, or preventing or treating autoimmune diseases.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: May 16, 2023
    Assignee: KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
    Inventors: Sang Taek Jung, Migyeong Jo, Sanghwan Ko, Bora Hwang
  • FLAVIN MONONUCLEOTIDE-BINDING PROTEIN VARIANTS HAVING IMPROVED FLUORESCENCE INTENSITY DERIVED FROM ARABIDOPSIS THALIANA
    Publication number: 20220267387
    Abstract: The present invention relates to flavoprotein improved LOV (iLOV) variants that exhibit enhanced fluorescence intensity compared to iLOV. The present invention also relates to a method for screening any of the iLOV variants. The iLOV variants of the present invention are useful in determining whether target proteins are expressed, irrespective of the presence of oxygen, and isolating and purifying the expressed target proteins due to their enhanced fluorescence intensity and quantum yield compared to existing LOV or iLOV proteins.
    Type: Application
    Filed: September 29, 2020
    Publication date: August 25, 2022
    Applicants: KOREA UNIVERSITY RESEARCH AND BUSINESSE FOUNDATION, KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
    Inventors: Sang Taek JUNG, Sang Hwan KO, Bora HWANG, Jung-Hyun NA
  • FC-GAMMA RECEPTOR MUTANTS
    Publication number: 20200408778
    Abstract: The present disclosure relates to a polypeptide including an Fc-gamma receptor mutant. The Fc-gamma receptor mutant of the present disclosure is optimized by substituting a part of an amino acid sequence of an Fc-gamma receptor with a different amino acid sequence, so as to provide an excellent selective binding ability to immunoglobulins. Therefore, it can be usefully used for increasing in vivo half-life of drugs, detecting and purifying immunoglobulins, inhibiting organ transplant rejections, or preventing or treating autoimmune diseases.
    Type: Application
    Filed: September 13, 2018
    Publication date: December 31, 2020
    Applicant: KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
    Inventors: Sang Taek JUNG, Migyeong JO, Sanghwan KO, Bora HWANG