Patents by Inventor Borbala Gesser

Borbala Gesser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and tools for identification of RSK/MSK kinase inhibitors
    Patent number: 9534209
    Abstract: The present invention concerns 3D-crystals of complexes of ribosomal S6 kinase (RSK) and mitogen- and stress-activated protein kinase (MSK) proteins and their ligands, as well as methods for crystallization, three-dimensional structure determination and structure assisted methods for identifying ligands of said proteins.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: January 3, 2017
    Assignees: Aarhus Universitet, Region Midtjylland
    Inventors: Jacob Lauwring Andersen, Borbala Gesser, Poul Nissen, Lars Iversen
  • METHODS AND TOOLS FOR IDENTIFICATION OF RSK/MSK KINASE INHIBITORS
    Publication number: 20150247133
    Abstract: The present invention concerns 3D-crystals of complexes of ribosomal S6 kinase (RSK) and mitogen- and stress-activated protein kinase (MSK) proteins and their ligands, as well as methods for crystallisation, three-dimensional structure determination and structure assisted methods for identifying ligands of said proteins.
    Type: Application
    Filed: September 30, 2013
    Publication date: September 3, 2015
    Inventors: Jacob Lauwring Andersen, Borbala Gesser, Poul Nissen, Lars Iversen
  • Synthetic IL-10 analogues
    Patent number: 6936586
    Abstract: The nonapeptide NH2-Ala-Tyr-Met-Thr-Met-Lys-Ile-Arg-Asn-COOH (SEQ ID NO: 1) and related molecules are useful as IL-10 agonists.
    Type: Grant
    Filed: January 16, 1997
    Date of Patent: August 30, 2005
    Assignee: Steeno Research Group A/S
    Inventors: Christian Grønhøj Larsen, Borbala Gesser
  • Immunomodulators
    Patent number: 6599501
    Abstract: The nonapeptide Ala-Tyr-Met-Thr-Met-Lys-Ile-Arg-Asn (SEQ ID NO:19) and certain related substances are useful as immunomodulators.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: July 29, 2003
    Assignee: Steeno Research Group A/S
    Inventors: Christian Grønhøj Larsen, Borbala Gesser
  • Antibodies that bind immunomodulators
    Patent number: 6168791
    Abstract: This invention relates to a polypeptide other than human interleukin (10) which has at least one of the following properties: a) induces inhibition of spontaneous IL-8 production by human monocytes, b) induces inhibition of IL-1 beta induced IL-8 production by human peripheral blood mononuclear cells (PBMC), c) induces production of interleukin-1 receptor antagonistic protein (IRAP) by human monocytes, d) induces chemotactic migration of CD8+ human T lymphocytes in vitro, e) desensitizes human CDS+ T cells resulting in an unresponsiveness towards rhIL-10,f) suppresses the chemotactic response of CD4+ T human lymphocytes towards IL-8, g) suppresses the chemotactic response of human monocytes towards MCAF/MCP-1, h) induces the production of IL-4 by cultured normal human CD4+ T cells, i) reduces the TNF alpha production in human mixed leukocyte reaction.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: January 2, 2001
    Assignee: Steeno Research Group A/S
    Inventors: Christian Grønhøj Larsen, Borbala Gesser
  • Immunomodulators
    Patent number: 6159937
    Abstract: The nonapeptide Ala-Tyr-Met-Thr-Met-Lys-Ile-Arg-Asn (SEQ ID NO:1) and certain related substances are useful as immunomodulators.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: December 12, 2000
    Assignee: Steeno Research Group A/S
    Inventors: Christian Gr.o slashed.nh.o slashed.j Larsen, Borbala Gesser