Abstract: A method for modifying an interstitial surface separating recesses from one another can include flowing a first fluid over the interstitial surface and into the recesses, such that the interstitial surface is substantially coated with the first fluid and the recesses are substantially filled with the first fluid; and while the first fluid remains within the recesses, replacing the first fluid coating the interstitial surface with a second fluid comprising a reagent.

Abstract: A method for manufacturing a composition for controlled release including multiple steps is provided. Firstly, an inclusion and a polymer aqueous solution are provided. The polymer aqueous solution has weight percentage ranging from 0.4% to 2%. Then, the inclusion is mixed with the polymer aqueous solution well so as to form a mixture; a molding process is performed on the mixture to form a plurality of colloids. Next, a cross-linking process is performed to conduct a reaction between the colloids and an aqueous solution having divalent metal ion so as to form a plurality of reticular structures. Finally, a drying process is performed on the reticular structures. A composition for controlled release is also provided.