Patents by Inventor Boris Chizh

Boris Chizh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical formulations comprising N,N?-disubstituted piperazine compounds
    Patent number: 7816358
    Abstract: Pharmaceutical formulations comprising N,N?disubstituted piperazine compounds and related methods of treatment using these formulations.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: October 19, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Heinz Uragg, Corinna Maul, Helmut Buschmann, Bernd Sundermann, Michael Haubrand, Boris Chizh
  • Sulfonylguanidine compounds and pharmaceutical uses thereof
    Patent number: 7671074
    Abstract: Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine compounds have an affinity for the gabapentin binding site and can be used to treat conditions such as pain, epilepsy, migraine and others.
    Type: Grant
    Filed: May 1, 2007
    Date of Patent: March 2, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Matthias Gerlach, Heinz Uragg, Michael Haurand, Claudia Katharina Puetz, Corinna Sundermann, Boris Chizh
  • SULFONYLGUANIDINE COMPOUNDS AND PHARMACEUTICAL USES THEREOF
    Publication number: 20080085900
    Abstract: Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine compounds have an affinity for the gabapentin binding site and can be used to treat conditions such as pain, epilepsy, migraine and others.
    Type: Application
    Filed: May 1, 2007
    Publication date: April 10, 2008
    Applicant: GRUENENTHAL GmbH
    Inventors: MATTHIAS GERLACH, Heinz Uragg, Michael Haurand, Claudia Puetz, Corinna Sundermann, Boris Chizh
  • Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine
    Patent number: 7034041
    Abstract: Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine (compounds), methods for the production thereof, pharmaceutical compositions containing said compounds, and methods of treatment of pain and other diseases using the pharmaceutical compositions.
    Type: Grant
    Filed: March 7, 2003
    Date of Patent: April 25, 2006
    Assignee: Gruenenthal GmbH
    Inventors: Boris Chizh, Michael Sattlegger, Claudia Hinze, Bernd Sundermann, Angelika Kerwer-Thomas, Gisela Henn
  • Substituted 1-aminobutan-3-ol compounds
    Patent number: 7022739
    Abstract: Substituted 1-aminobutane-3-ol compounds, methods for producing them, pharmaceutical compounds containing them, and the use of substituted 1-aminobutane-3-ol compounds for producing pharmaceutical compounds.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: April 4, 2006
    Assignee: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Corinna Maul, Bernd Sundermann, Utz-Peter Jagusch, Michael Haurand, Boris Chizh
  • Pharmaceutical formulations comprising N,N'-disubstituted piperazine compounds
    Publication number: 20050038034
    Abstract: Pharmaceutical formulations comprising N,N?disubstituted piperazine compounds and related methods of treatment using these formulations.
    Type: Application
    Filed: June 14, 2004
    Publication date: February 17, 2005
    Applicant: Grunenthal GmbH
    Inventors: Heinz Uragg, Corinna Maul, Helmut Buschmann, Bernd Sundermann, Michael Haurand, Boris Chizh
  • ?-thioamino acids
    Patent number: 6846843
    Abstract: Thio-alpha-amino acids of general formula (I), wherein R1, R2 and R3 have the meanings given in the description, methods for producing them, and medicaments containing these compounds. The invention also provides methods for treating pain and other diseases using the pharmaceutical compositions comprising the thioamino acids.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: January 25, 2005
    Assignee: Gruenenthal GmbH
    Inventors: Boris Chizh, Matthias Gerlach, Michael Haurand, Claudia Puetz, Gero Gaube, D. Enders
  • 5-Amino-1-pentene-3-ol substituted derivatives
    Patent number: 6815443
    Abstract: The invention relates to 5-amino-1-pentene-3-ol substituted derivatives, a method for the production thereof, medicaments containing said compounds, the use of substituted 5-amino-1-pentene-3-ol derivatives for the production of medicaments, and methods of treatment using the medicaments.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: November 9, 2004
    Assignee: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Corinna Maul, Bernd Sundermann, Utz-Peter Jagusch, Michael Haurand, Boris Chizh
  • Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments
    Patent number: 6784175
    Abstract: The use of at least one substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compound and/or one of the enantiomers thereof and/or one of the diastereomers thereof and/or one of the physiologically acceptable salts thereof for producing a medicament that has an N-methyl-D-aspartate-(NMDA)-antagonistic effect.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: August 31, 2004
    Assignee: Gruenenthal GmbH
    Inventors: Bernd Sundermann, Werner Englberger, Boris Chizh
  • Active substance combination containing a compound with an opioid effect and at least one further compound of formula 1
    Publication number: 20040116352
    Abstract: The invention relates to an active substance combination that contains a compound with an opioid effect and at least one further compound of the general formula (I) and/or one of its diastereomers and/or one of its enantiomers and/or at least one corresponding physiologically acceptable salt thereof. The invention further relates to medicaments that contain the inventive active substance combination, to pharmaceutical formulations that contain the active substance combination and to the use of the active substance combination for producing a medicament.
    Type: Application
    Filed: November 25, 2002
    Publication date: June 17, 2004
    Inventors: Boris Chizh, Thomas Christoph, Babette-Yvonne Koegel, Achim Schuettler, Oswald Zimmer
  • Active substance combination containing an opioid having a fentanyl-type structure and ketamine
    Publication number: 20040092531
    Abstract: The invention relates to an active substance combination that contains as the active substance component a) at least one opioid compound that has a fentanyl-type structure and/or the enantiomers and/or the diastereomers thereof and/or at least one corresponding pharmaceutically acceptable salt, and as the active substance component b) ketamine and/or at least one of its physiologically acceptable salts. The weight ratio of active substance component a) to active substance component b) ranges from 1:20 to 1:1500. The invention also relates to medicament formulations and medicaments that contain the inventive active substance combination and to the use of said active substance combination for producing medicaments.
    Type: Application
    Filed: November 22, 2002
    Publication date: May 13, 2004
    Inventors: Boris Chizh, Thomas Christoph, Werner Englberger
  • Beta-thioamino acids
    Publication number: 20030236253
    Abstract: Thio-alpha-amino acids of general formula (I), wherein R1, R2 and R3 have the meanings given in the description, methods for producing them, and medicaments containing these compounds. The invention also provides methods for treating pain and other diseases using the pharmaceutical compositions comprising the thioamino acids.
    Type: Application
    Filed: March 14, 2003
    Publication date: December 25, 2003
    Applicant: Gruenenthal GmbH
    Inventors: Boris Chizh, Matthias Gerlach, Michael Haurand, Claudia Puetz, Gero Gaube, D. Enders
  • Pain treatment methods and compositions
    Publication number: 20030229145
    Abstract: The invention relates to amino acids, a method for the production thereof, medicaments containing said amino acids and the use of amino acids in the production of medicaments for treating pain.
    Type: Application
    Filed: March 31, 2003
    Publication date: December 11, 2003
    Applicant: GRUENENTHAL GMBH
    Inventors: Boris Chizh, Katharina Claudia Puetz, Michael Haurand
  • Sulfonylguanidine compounds and pharmaceutical uses thereof
    Publication number: 20030225084
    Abstract: Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine compounds have an affinity for the gabapentin binding site and can be used to treat conditions such as pain, epilepsy, migraine and others.
    Type: Application
    Filed: March 31, 2003
    Publication date: December 4, 2003
    Applicant: Gruenenthal GmbH
    Inventors: Matthias Gerlach, Heinz Uragg, Michael Haurand, Claudia Katharina Puetz, Corinna Maul, Boris Chizh
  • Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine
    Publication number: 20030225116
    Abstract: Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine (compounds), methods for the production thereof, pharmaceutical compositions containing said compounds, and methods of treatment of pain and other diseases using the pharmaceutical compositions.
    Type: Application
    Filed: March 7, 2003
    Publication date: December 4, 2003
    Applicant: Gruenental GmbH
    Inventors: Boris Chizh, Michael Sattlegger, Claudia Hinze, Bernd Sundermann, Angelika Kerwer-Thomas, Gisela Henn
  • 5-Amino-1-pentene-3-ol substituted derivatives
    Publication number: 20030220390
    Abstract: The invention relates to 5-amino-1-pentene-3-ol substituted derivatives, a method for the production thereof, medicaments containing said compounds, the use of substituted 5-amino-1-pentene-3-ol derivatives for the production of medicaments, and methods of treatment using the medicaments.
    Type: Application
    Filed: March 31, 2003
    Publication date: November 27, 2003
    Applicant: GRUENENTHAL GMBH
    Inventors: Helmut Buschmann, Corinna Maul, Bernd Sundermann, Utz-Peter Jagusch, Michael Haurand, Boris Chizh
  • Substituted 1-aminobutan-3-ol compounds
    Publication number: 20030216393
    Abstract: Substituted 1-aminobutane-3-ol compounds, methods for producing them, pharmaceutical compounds containing them, and the use of substituted 1-aminobutane-3-ol compounds for producing pharmaceutical compounds.
    Type: Application
    Filed: March 28, 2003
    Publication date: November 20, 2003
    Applicant: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Corinna Maul, Bernd Sundermann, Utz-Peter Jagusch, Michael Haurand, Boris Chizh
  • Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments
    Publication number: 20030181450
    Abstract: The invention relates to the use of at least one substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenyl-hexane-3-ol compound and/or one of the enantiomers thereof and/or one of the diastereomers thereof and/or one of the physiologically acceptable salts thereof for producing a medicament that has an N-methyl-D-aspartate-(NMDA)-antagonistic effect.
    Type: Application
    Filed: November 18, 2002
    Publication date: September 25, 2003
    Inventors: Bernd Sundermann, Werner Engleberger, Boris Chizh
  • Medicament for combating respiratory depression
    Publication number: 20030130203
    Abstract: The invention relates to the use of at least one compound of general formula (I) and/or one of its diastereomers and/or one of its enantiomers and/or one of the corresponding physiologically compatible salts for producing a medicament for combating respiratory depression, with the exception of medicaments for combating respiratory depression as a cause of sleep apnea.
    Type: Application
    Filed: November 21, 2002
    Publication date: July 10, 2003
    Inventors: Thomas Christoph, Boris Chizh, Oswald Zimmer