Abstract: Apparatus is provided that includes a retinal stimulator, which includes an electrode array including electrodes, which are configured to be coupled to a retina of a subject's eye; and driving circuitry, configured to drive the electrodes to apply currents to the retina. The retinal stimulator further includes an elastic anchor that is coupled to the retinal stimulator and is configured to anchor the electrodes to the retina without the elastic anchor penetrating the retina. Other embodiments are also described.

Abstract: Apparatus (20, 420) is provided that includes a retinal implant (40), configured for implantation on a retina (306) of a subject's eye (300) in an epi-retinal position; and an anchor (60, 460, 660) shaped to define (i) an anterior portion (70, 470, 670), (ii) a posterior portion (90, 490, 690) coupled to the retinal implant (40), and (iii) a middle portion (80, 480, 680) extending longitudinally between the anterior portion (70, 470, 670) and the posterior portion (90, 490, 690). The anchor (60, 460, 660) is configured to anchor the retinal implant (40) to the retina (306) such that when the retinal implant (40) is implanted on the retina (306), the anterior portion (70, 470, 670) of the anchor (60, 460, 660) is mounted against a ciliary sulcus (310) of the eye (300). Other embodiments are also described.

Abstract: Apparatus is provided that includes a retinal stimulator, which includes an electrode array including electrodes, which are configured to be coupled to a retina of a subject's eye; and driving circuitry, configured to drive the electrodes to apply currents to the retina. The retinal stimulator further includes an elastic anchor that is coupled to the retinal stimulator and is configured to anchor the electrodes to the retina without the elastic anchor penetrating the retina. Other embodiments are also described.

Abstract: A method of securing an assembly of a drug delivery system, comprising: configuring at least a first component and a second component of the assembly in a closed configuration ready for placement into the drug delivery system; installing an assembly key including a locking element on the assembly to secure the assembly in said configuration; and, transporting the assembly with the assembly key installed.

Abstract: A method of securing an assembly of a drug delivery system, comprising: configuring at least a first component and a second component of the assembly in a closed configuration ready for placement into the drug delivery system; installing an assembly key including a locking element on the assembly to secure the assembly in said configuration; and, transporting the assembly with the assembly key installed.

Abstract: A method is provided for implanting, in an eye of a subject, an implantable retinal stimulator having (i) an electrode array including electrodes; (ii) a plurality of photosensors; and (iii) driving circuitry, configured to drive the electrodes to apply currents to a retina of the eye. A surface of the retina is contacted with a tissue-contact surface of an anchoring-element-receiving portion of a frame. Subsequently, the frame is anchored to the retina by penetrating scleral tissue of the subject by advancing an anchoring element through an opening defined by the anchoring-element-receiving portion of the frame and into the scleral tissue such that the anchoring element secures the frame to the retina. Subsequently, using the frame, the implantable retinal stimulator is positioned in an epi-retinal position such that the electrode array penetrates the retina. Other embodiments are also described.

Abstract: Apparatus is provided including an implantable retinal stimulator, for implantation on a retina of an eye, and including (i) an electrode array including electrodes; (ii) a plurality of photosensors; and (iii) driving circuitry, configured to drive the electrodes to apply currents to the retina. The apparatus further includes an interface member disposed at an outer surface of the implantable retinal stimulator, e.g., a peripheral member surrounding at least a portion of the implantable retinal stimulator. The apparatus additionally includes a frame, (i) shaped and sized to couple to the peripheral member and to surround the implantable retinal stimulator at least in part, and (ii) shaped to define at least a first anchoring element receiving portion. An anchoring element is shaped and sized to be positioned in the anchoring element receiving portion and to penetrate scleral tissue of the subject. Other applications are also described.

Abstract: A variable flexibility adhesive system may adhere a surface of a medical infusion device to the skin of a user. The system may be configured to hold a location on the surface stationary with respect to a site on the user's skin. The system may include an adhesive substrate for adhering to the user and an interface where the substrate is held to the surface of the device. The interface may totally and/or partially surround the stationary location. A skirt of the substrate may totally and/or partially surround the interface. Parts of the skirt may be stiffened. Optional features may include tabs for activation of the adhesive and/or a location for peeling the infuser away from the skin. Additionally or alternatively, the interface may have variable flexibility. Additionally or alternatively, the stiffener may include a plastic layer.

Abstract: Apparatus is provided including an implantable retinal stimulator, for implantation on a retina of an eye, and including (i) an electrode array including electrodes; (ii) a plurality of photosensors; and (iii) driving circuitry, configured to drive the electrodes to apply currents to the retina. The apparatus further includes an interface member disposed at an outer surface of the implantable retinal stimulator, e.g., a peripheral member surrounding at least a portion of the implantable retinal stimulator. The apparatus additionally includes a frame, (i) shaped and sized to couple to the peripheral member and to surround the implantable retinal stimulator at least in part, and (ii) shaped to define at least a first anchoring element receiving portion. An anchoring element is shaped and sized to be positioned in the anchoring element receiving portion and to penetrate scleral tissue of the subject. Other applications are also described.

Abstract: A method of securing an assembly of a drug delivery system, comprising: configuring at least a first component and a second component of the assembly in a closed configuration ready for placement into the drug delivery system; installing an assembly key including a locking element on the assembly to secure the assembly in said configuration; and, transporting the assembly with the assembly key installed.

Abstract: A variable flexibility adhesive system may adhere a surface of a medical infusion device to the skin of a user. The system may be configured to hold a location on the surface stationary with respect to a site on the user's skin. The system may include an adhesive substrate for adhering to the user and an interface where the substrate is held to the surface of the device. The interface may totally and/or partially surround the stationary location. A skirt of the substrate may totally and/or partially surround the interface. Parts of the skirt may be stiffened. Optional features may include tabs for activation of the adhesive and/or a location for peeling the infuser to away from the skin. Additionally or alternatively, the interface may have variable flexibility. Additionally or alternatively, the stiffener may include a plastic layer.

Abstract: An apparatus for use with a biologically-compatible-fluid pressure source, the apparatus includes an elongate carrier, adapted to be inserted through a proximal opening of a body lumen, and a piston head coupled to a distal portion of the carrier. The piston head is adapted to form a pressure seal with a wall of the lumen after the carrier has been inserted into the lumen, and to be advanced distally through the body lumen in response to pressure from the fluid pressure source. The apparatus is configured to facilitate distal advancement of the piston head by facilitating passage of fluid out of the lumen from a site within the lumen distal to the piston head.

Abstract: An apparatus for use with a biologically-compatible-fluid pressure source, the apparatus includes an elongate carrier, adapted to be inserted through a proximal opening of a body lumen, and a piston head coupled to a distal portion of the carrier. The piston head is adapted to form a pressure seal with a wall of the lumen after the carrier has been inserted into the lumen, and to be advanced distally through the body lumen in response to pressure from the fluid pressure source. The apparatus is configured to facilitate distal advancement of the piston head by facilitating passage of fluid out of the lumen from a site within the lumen distal to the piston head.