Patents by Inventor Boris Epel

Boris Epel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260027385
    Abstract: A system for mapping oxygen levels in tumors includes a needle that is sized to deliver high dose rate brachytherapy to tissue into which the needle is inserted, where the needle includes a radio frequency micro-coil sensor positioned within a shaft of the needle and a spin probe mounted to an outer surface of the shaft of the needle. A processor is in communication with the needle and configured to move the radio frequency micro-coil sensor along the shaft of the needle. The processor is also configured to receive, from the radio frequency micro-coil sensor, oxygen level readings at a plurality of tissue locations along the shaft of the needle. The processor is also configured to generate an oxygen level mapping of the tissue based on the oxygen level readings received from the radio frequency micro-coil sensor.
    Type: Application
    Filed: July 25, 2025
    Publication date: January 29, 2026
    Inventors: Bulent Aydogan, Boris Epel, Howard Halpern, Erik Pearson, Daniela Olivera Velarde, Subramanian Sundramoorthy
  • Patent number: 12440119
    Abstract: An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.
    Type: Grant
    Filed: February 21, 2025
    Date of Patent: October 14, 2025
    Inventors: Howard J. Halpern, Boris Epel
  • Publication number: 20250204804
    Abstract: An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.
    Type: Application
    Filed: February 21, 2025
    Publication date: June 26, 2025
    Inventors: Howard J. Halpern, Boris Epel
  • Patent number: 12232858
    Abstract: An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.
    Type: Grant
    Filed: March 28, 2023
    Date of Patent: February 25, 2025
    Inventors: Howard J. Halpern, Boris Epel
  • Publication number: 20240341617
    Abstract: An oxygen sensing system includes a coupling loop that connects to an electron paramagnetic resonance (EPR) bridge. The oxygen sensing system also includes a cable connected to the coupling loop, where the cable acts as a transmission line. The oxygen sensing system further includes a plurality of oxygen sensors formed on the cable, where each of the oxygen sensors comprises a multi-turn coil.
    Type: Application
    Filed: April 15, 2024
    Publication date: October 17, 2024
    Inventors: Bulent Aydogan, Howard Halpern, Subramanian Sundramoorthy, Erik Pearson, Boris Epel, Daniela Olivera Velarde, Ann Barry Flood, Harold M. Swartz, Wilson Schreiber
  • Publication number: 20230240553
    Abstract: An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.
    Type: Application
    Filed: March 28, 2023
    Publication date: August 3, 2023
    Inventors: Howard J. Halpern, Boris Epel
  • Patent number: 11612336
    Abstract: An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: March 28, 2023
    Inventors: Howard J. Halpern, Boris Epel
  • Patent number: 10551450
    Abstract: Techniques provide for passive Q switching in a bimodal resonator environment, where magnetic resonators are coupled for power transfer. A passive Q switch is responsive to a driving power from one magnetic resonator coupled to another magnetic resonator. After the driving power reaches a threshold, the passive Q switch shunts the receiving magnetic resonator, at least partially, to reduce the Q of that second resonator, which allows faster detection operation of the second resonator in some applications. The technique allows for fast Q switching in a bimodal resonator system, especially one having resonators having magnetic fields that are orthogonal to one another.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: February 4, 2020
    Assignee: THE UNIVERSITY OF CHICAGO
    Inventors: Howard Halpern, Subramanian V. Sundramoorthy, Boris Epel
  • Publication number: 20160324438
    Abstract: An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 10, 2016
    Inventors: Howard J. Halpern, Boris Epel
  • Patent number: 9392957
    Abstract: An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: July 19, 2016
    Inventors: Howard J. Halpern, Boris Epel
  • Publication number: 20150022209
    Abstract: Techniques provide for passive Q switching in a bimodal resonator environment, where magnetic resonators are coupled for power transfer. A passive Q switch is responsive to a driving power from one magnetic resonator coupled to another magnetic resonator. After the driving power reaches a threshold, the passive Q switch shunts the receiving magnetic resonator, at least partially, to reduce the Q of that second resonator, which allows faster detection operation of the second resonator in some applications. The technique allows for fast Q switching in a bimodal resonator system, especially one having resonators having magnetic fields that are orthogonal to one another.
    Type: Application
    Filed: June 14, 2012
    Publication date: January 22, 2015
    Applicant: THE UNIVERSITY OF CHICAGO
    Inventors: Howard Halpern, Subramanian V. Sundramoorthy, Boris Epel
  • Patent number: D1022209
    Type: Grant
    Filed: October 15, 2021
    Date of Patent: April 9, 2024
    Assignee: O2M Technologies, LLC
    Inventors: Boris Epel, Mrignayani Kotecha
  • Patent number: D1127609
    Type: Grant
    Filed: November 9, 2021
    Date of Patent: May 26, 2026
    Assignee: O2M Technologies, LLC
    Inventors: Boris Epel, Marcelo Gutierrez-Miranda