Patents by Inventor Boris Fedotev

Boris Fedotev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Candesartan cilexetil polymorphs
    Publication number: 20100121072
    Abstract: Provided are candesartan cilexetil forms and methods of their preparation. Also provided are pharmaceutical compositions prepared by combining at least one pharmaceutically-acceptable excipient with at least one candesartan cilexetil form of the invention.
    Type: Application
    Filed: January 13, 2010
    Publication date: May 13, 2010
    Inventors: Marina Yu Etinger, Boris Fedotev, Tamas Koltai, Ziv Kurgan, Omer Malachi
  • Candesartan cilexetil polymorphs
    Patent number: 7692023
    Abstract: Provided are candesartan cilexetil forms and methods of their preparation. Also provided are pharmaceutical compositions prepared by combining at least one pharmaceutically-acceptable execipient with at least one candesartan cilexetil form of the invention.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: April 6, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Marina Yu Etinger, Boris Fedotev, Tamas Koltai, Ziv Kurgan, Omer Malachi
  • Preparation of candesartan cilexetil
    Publication number: 20060252939
    Abstract: The invention encompasses processes for the synthesis of cilexetil trityl candesartan from the reaction of trityl candesartan with cilexetil halide in the presence of a base and a low boiling organic solvent. Optionally, the reaction may be conducted in the presence of a phase transfer catalyst.
    Type: Application
    Filed: July 12, 2006
    Publication date: November 9, 2006
    Inventors: Marina Etinger, Boris Fedotev, Ben-Zion Dolitzky
  • Preparation of candesartan cilexetil
    Patent number: 7098342
    Abstract: The invention encompasses processes for the synthesis of cilexetil trityl candesartan from the reaction of trityl candesartan with cilexetil halide in the presence of a base and a low boiling organic solvent. Optionally, the reaction may be conducted in the presence of a phase transfer catalyst.
    Type: Grant
    Filed: October 18, 2004
    Date of Patent: August 29, 2006
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Marina Yu Etinger, Boris Fedotev, Ben-Zion Dolitzky
  • Preparation of candesartan cilexetil in high purity
    Publication number: 20050250827
    Abstract: The present invention is directed to the preparation of substantially pure candesartan cilexetil by the deprotection of trityl candesartan cilexetil and crystallization and/or recrystallization of candesartan cilexetil.
    Type: Application
    Filed: October 15, 2004
    Publication date: November 10, 2005
    Inventors: Marina Etinger, Valerie Niddam-Hildesheim, Boris Fedotev, Ben-Zion Dolitzky
  • Candesartan cilexetil polymorphs
    Publication number: 20050250828
    Abstract: Provided are candesartan cilexetil forms and methods of their preparation. Also provided are pharmaceutical compositions prepared by combining at least one pharmaceutically-acceptable excipient with at least one candesartan cilexetil form of the invention.
    Type: Application
    Filed: February 11, 2005
    Publication date: November 10, 2005
    Inventors: Marina Etinger, Boris Fedotev, Tamas Koltai, Ziv Kurgan, Omer Malachi
  • Process for production of highly pure donepezil hydrochloride
    Publication number: 20050239837
    Abstract: Disclosed is a process for production of highly pure donepezil hydrochloride in the form of polymorph I that does not involve the isolation of donepezil base. The disclosed process involves intramolecular cyclization of N-benzyl-2-(3,4-dimethoxybenzyl)-3-(4-piperidine)propionic acid followed by treatment with HCl.
    Type: Application
    Filed: April 22, 2005
    Publication date: October 27, 2005
    Inventors: Arie Gutman, Marina Etinger, Boris Tishin, Boris Pertsikov, Boris Fedotev, Alexander Vilensky, Pavel Potyabin, Gennady Nisnevich
  • Preparation of candesartan cilexetil
    Publication number: 20050131037
    Abstract: The invention encompasses processes for the synthesis of cilexetil trityl candesartan from the reaction of trityl candesartan with cilexetil halide in the presence of a base and a low boiling organic solvent. Optionally, the reaction may be conducted in the presence of a phase transfer catalyst.
    Type: Application
    Filed: October 18, 2004
    Publication date: June 16, 2005
    Inventors: Marina Etinger, Boris Fedotev, Ben-Zion Dolitzky