Patents by Inventor Boris Gorine

Boris Gorine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorph of latrepirdine dihydrochloride
    Patent number: 12084440
    Abstract: The specification relates to a crystalline Latrepirdine dihydrochloride, Form DMB-I, method of its preparation, pharmaceutical composition containing it and its uses.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: September 10, 2024
    Assignee: BIGESPAS LTD.
    Inventors: Boris Gorine, Marina Yurovskaya
  • POLYMORPH OF LATREPIRDINE DIHYDROCHLORIDE
    Publication number: 20240124441
    Abstract: The specification relates to a crystalline Latrepirdine dihydrochloride, Form DMB-I, method of its preparation, pharmaceutical composition containing it and its uses.
    Type: Application
    Filed: January 31, 2022
    Publication date: April 18, 2024
    Inventors: Boris GORINE, Marina YUROVSKAYA
  • POLYMORPH OF LATREPIRDINE DIHYDROCHLORIDE
    Publication number: 20220242860
    Abstract: The specification relates to a crystalline Latrepirdine dihydrochloride, Form DMB-I, method of its preparation, pharmaceutical composition containing it and its uses.
    Type: Application
    Filed: February 1, 2021
    Publication date: August 4, 2022
    Inventors: Boris GORINE, Marina YUROVSKAYA
  • Phosphono-carboxylate compounds for treating amyloidosis
    Publication number: 20080004244
    Abstract: Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
    Type: Application
    Filed: August 2, 2007
    Publication date: January 3, 2008
    Applicant: Neurochem (International) Limited
    Inventors: Walter Szarek, Xianqi Kong, Gregory Thatcher, Boris Gorine
  • Phosphono-carboxylate compounds for treating amyloidosis
    Publication number: 20060135479
    Abstract: Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
    Type: Application
    Filed: October 7, 2005
    Publication date: June 22, 2006
    Inventors: Walter Szarek, Xianqi Kong, Gregory Thatcher, Boris Gorine
  • Phosphono-carboxylate compounds for treating amyloidosis
    Publication number: 20040138178
    Abstract: Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
    Type: Application
    Filed: May 27, 2003
    Publication date: July 15, 2004
    Applicant: Queen's University at Kingston
    Inventors: Walter A. Szarek, Xianqi Kong, Gregory R.J. Thatcher, Boris Gorine
  • Phosphono-carboxylate compounds for treating amyloidosis
    Publication number: 20030027796
    Abstract: Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
    Type: Application
    Filed: August 23, 2002
    Publication date: February 6, 2003
    Applicant: Lahive & Cockfield, LLP
    Inventors: Walter A. Szarek, Xianqi Kong, Gregory R.J. Thatcher, Boris Gorine
  • Phosphono-carboxylate compounds for treating amyloidosis
    Patent number: 6440952
    Abstract: Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: August 27, 2002
    Assignee: Queen's University at Kingston
    Inventors: Walter A. Szarek, Xianqi Kong, Gregory R. J. Thatcher, Boris Gorine
  • Phosphono-carboxylate compounds for treating amyloidosis
    Publication number: 20010027186
    Abstract: Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
    Type: Application
    Filed: May 17, 2001
    Publication date: October 4, 2001
    Applicant: Queen's University at Kingston
    Inventors: Walter A. Szarek, Xianqi Kong, Gregory R.J Thatcher, Boris Gorine