Patents by Inventor Boris PuFong

Boris PuFong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Control of gene expression using a complex of an oligonucleotide and a regulatory peptide
    Publication number: 20050136040
    Abstract: A method for suppressing the expression of a selected gene in a cell the method comprising introducing into the cell a molecule comprising (1) a nucleic acid binding portion which binds to a site or associated with the selected gene which site is present in a genome and (2) an expression repressor portion, wherein the nucleic acid binding portion comprises an oligonucleotide or oligonucleotide mimic or analogue, and wherein the repressor portion comprises a polypeptide or peptidomimetic. Molecules for use in the methods of the invention are provided. The repressor may be a portion of a histone deacetylase or DNA methylase or polypeptide capable of recruiting a histone deacetylase or DNA methylase.
    Type: Application
    Filed: April 8, 2004
    Publication date: June 23, 2005
    Applicant: Imperial College Innovations Limited
    Inventors: Stephen Hart, Simak Ali, Boris PuFong, Andrew Porter, Laki Buluwela, Satu Vainikka, John Jenkinson, Patrick Kanda