Patents by Inventor Boris Zaslavsky
Boris Zaslavsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120245856Abstract: The invention involves obtaining signatures of species (including chemical, biological, or biochemical molecules) and/or signatures of interactions between species and using them to characterize species, characterize interactions, and/or identify species that could be useful in a variety of settings. Signatures can be obtained using aqueous multi-phase partitioning and can be used to predict molecular interactions for applications such as drug discovery. A plurality of aqueous multi-phase partitioning arrangements can define an overall system providing an information-intensive signature, maximizing precision and sensitivity.Type: ApplicationFiled: June 5, 2012Publication date: September 27, 2012Applicant: Analiza, Inc.Inventors: Arnon Chait, Boris Zaslavsky
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Publication number: 20110218738Abstract: The invention involves obtaining signatures of species (including chemical, biological, or biochemical molecules) and/or signatures of interactions between species and using them to characterize species, characterize interactions, and/or identify species that could be useful in a variety of settings. Signatures can be obtained using aqueous multi-phase partitioning and can be used to predict molecular interactions for applications such as drug discovery. A plurality of aqueous multi-phase partitioning arrangements can define an overall system providing an information-intensive signature, maximizing precision and sensitivity.Type: ApplicationFiled: May 18, 2011Publication date: September 8, 2011Applicant: Analiza, Inc.Inventors: Arnon Chait, Boris Zaslavsky
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Patent number: 7968350Abstract: The invention involves obtaining signatures of species (including chemical, biological, or biochemical molecules) and/or signatures of interactions between species and using them to characterize species, characterize interactions, and/or identify species that could be useful in a variety of settings. Signatures can be obtained using aqueous multi-phase partitioning and can be used to predict molecular interactions for applications such as drug discovery. A plurality of aqueous multi-phase partitioning arrangements can define an overall system providing an information-intensive signature, maximizing precision and sensitivity.Type: GrantFiled: November 12, 2002Date of Patent: June 28, 2011Assignee: Analiza, Inc.Inventors: Arnon Chait, Boris Zaslavsky
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Publication number: 20080050831Abstract: The present invention generally provides systems and methods for the detection, identification, or characterization of differences between properties or behavior of corresponding species in two or more mixtures comprised of molecules, including biomolecules and/or molecules able to interact with biomolecules, using techniques such as partitioning. The experimental conditions established as distinguishing between the mixtures of the molecules using the systems and methods of the invention can also be used, in some cases, for further fractionation and/or characterization of the biomolecules and/or other molecules, using techniques such as single-step or multiple-step extraction, and/or by liquid-liquid partition chromatography. The methods could also be used for discovering and identifying markers associated with specific diagnostics, and can be used for screening for such markers once discovered and identified during diagnostics screening.Type: ApplicationFiled: June 15, 2007Publication date: February 28, 2008Applicant: Analiza, Inc.Inventors: Arnon Chait, Boris Zaslavsky
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Publication number: 20070198194Abstract: The present invention is generally related to the separation, fractionation, and/or characterization of molecules and/or biomolecules in one or more mixtures. After fractionation, different phases of a partitioning system can be analyzed via an analytical technique such as spectral analysis, chromatography, or the like, to produce a spectrum or other symbolic representation of the species after fractionation, and the spectra of the various fractions/phases compared to define a comparative spectrum as a marker or otherwise providing information about the sample, including such information that is independent of the original level of abundance of the molecules in the mixture. Comparative spectra of various samples can be compared to each other and/or to controls or reference spectra and/or comparative spectra to determine a variety of information.Type: ApplicationFiled: December 19, 2006Publication date: August 23, 2007Applicant: Analiza, Inc.Inventors: Arnon Chait, Boris Zaslavsky
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Publication number: 20070128618Abstract: The present invention generally provides systems and methods for the detection, identification, or characterization of differences between properties or behavior of corresponding species in two or more mixtures comprised of molecules, including biomolecules and/or molecules able to interact with biomolecules, using techniques such as partitioning. The experimental conditions established as distinguishing between the mixtures of the molecules using the systems and methods of the invention can also be used, in some cases, for further fractionation and/or characterization of the biomolecules and/or other molecules, using techniques such as single-step or multiple-step extraction, and/or by liquid-liquid partition chromatography. The methods could also be used for discovering and identifying markers associated with specific diagnostics, and can be used for screening for such markers once discovered and identified during diagnostics screening.Type: ApplicationFiled: May 24, 2006Publication date: June 7, 2007Applicant: Analiza, Inc.Inventors: Arnon Chait, Boris Zaslavsky
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Publication number: 20070048786Abstract: Methods for proteomics analysis, including fractionation or separation of one or more biomolecules that exist in a mixture, for example, using aqueous multi-phase partitioning, which results in isolation of one or more preselected biomolecules, followed by further proteomics analysis.Type: ApplicationFiled: September 1, 2005Publication date: March 1, 2007Inventors: Arnon Chait, Boris Zaslavsky
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Publication number: 20060269964Abstract: The present invention generally provides systems and methods for the detection, identification, or characterization of differences between properties or behavior of corresponding species in two or more mixtures comprised of molecules, including biomolecules and/or molecules able to interact with biomolecules, using techniques such as partitioning. The experimental conditions established as distinguishing between the mixtures of the molecules using the systems and methods of the invention can also be used, in some cases, for further fractionation and/or characterization of the biomolecules and/or other molecules, using techniques such as single-step or multiple-step extraction, and/or by liquid-liquid partition chromatography. The methods could also be used for discovering and identifying markers associated with specific diagnostics, and can be used for screening for such markers once discovered and identified during diagnostics screening.Type: ApplicationFiled: June 14, 2004Publication date: November 30, 2006Inventors: Arnon Chait, Boris Zaslavsky
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Publication number: 20030162224Abstract: The invention involves obtaining signatures of species (including chemical, biological, or biochemical molecules) and/or signatures of interactions between species and using them to characterize species, characterize interactions, and/or identify species that could be useful in a variety of settings. Signatures can be obtained using aqueous multi-phase partitioning and can be used to predict molecular interactions for applications such as drug discovery. A plurality of aqueous multi-phase partitioning arrangements can define an overall system providing an information-intensive signature, maximizing precision and sensitivity.Type: ApplicationFiled: November 12, 2002Publication date: August 28, 2003Inventors: Arnon Chait, Boris Zaslavsky