Patents by Inventor Borivoj Vojtesek

Borivoj Vojtesek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic applications of p53 isoforms in regenerative medicine, aging and cancer
    Patent number: 9944927
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: April 17, 2018
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The University of Dundee, Masaryk Memorial Cancer Institute
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane
  • Therapeutic applications of P53 isoforms in regenerative medicine, aging and cancer
    Patent number: 9068165
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: June 30, 2015
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, The University of Dundee, Masaryk Memorial Cancer Institute
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane
  • Substituted 6-(2-aminobenzylamino)purine derivatives, their use as medicaments and preparations containing these compounds
    Patent number: 9023857
    Abstract: The invention relates to new substituted 6-(2-aminobenzylamino)purines, represented by the general formula I, which can be used in CDK inhibition, in particular, in the treatment of viral infections and diseases involving cell proliferation. The invention further includes pharmaceutical preparations containing substituted 6-(2-aminobenzylamino)purines.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: May 5, 2015
    Assignee: Univerzita Palackeho V Olomouci
    Inventors: Libor Havlicek, Vladimir Krystof, Marek Zatloukal, Karel Dolezal, Miroslav Strnad, Borivoj Vojtesek
  • Therapeutic applications of p53 isoforms in regenerative medicine, aging and cancer
    Patent number: 8575121
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Grant
    Filed: October 21, 2008
    Date of Patent: November 5, 2013
    Assignees: The United States of America as represented by the Secetary of the Department of Health and Human Services, The University of Dundee, Masaryk Memorial Cancer Institute
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane
  • Substitution derivatives of N-benzyladenosine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds
    Patent number: 8119614
    Abstract: The invention concerns novel substitution derivatives of N6-benzyladenosine having anticancer, mitotic, immunosuppressive and antisenescent properties for plant, animal and human cells. This invention also relates to the methods of preparation of these N6-benzyladenosine derivatives and their use as drugs, cosmetic preparations and growth regulators comprising these derivatives as active compound and use of these derivatives for preparation of pharmaceutical compositions, in biotechnological processes, in cosmetics and in agriculture.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: February 21, 2012
    Assignee: Ustav Experimentalni Botaniky Akademie Ved Ceske Republiky
    Inventors: Karel Dolezal, Igor Popa, Marek Zatloukal, René Lenobel, Dana Hradecká, Borivoj Vojtesek, Stjepan Uldrijan, Petr Mlejnek, Stefaan Werbrouck, Miroslav Strnad
  • SUBSTITUTED 6-(2-AMINOBENZYLAMINO)PURINE DERIVATIVES, THEIR USE AS MEDICAMENTS AND PREPARATIONS CONTAINING THESE COMPOUNDS
    Publication number: 20110287111
    Abstract: The invention relates to new substituted 6-(2-aminobenzylamino)purines, represented by the general formula I, which can be used in CDK inhibition, in particular, in the treatment of viral infections and diseases involving cell proliferation. The invention further includes pharmaceutical preparations containing substituted 6-(2-aminobenzylamino)purines.
    Type: Application
    Filed: January 22, 2010
    Publication date: November 24, 2011
    Inventors: Libor Havlicek, Vladimir Krystof, Marek Zatloukal, Karel Dolezal, Miroslav Strnad, Borivoj Vojtesek
  • THERAPEUTIC APPLICATIONS OF P53 ISOFORMS IN REGENERATIVE MEDICINE, AGING AND CANCER
    Publication number: 20110243968
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Application
    Filed: October 21, 2008
    Publication date: October 6, 2011
    Applicant: THE GOV'T OF THE U.S. OF AMERICA REPRESENTED BY THE SECRETARY OF THE DEPT H&HS
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane
  • Substitution derivatives of n6-benzyladenosine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds
    Publication number: 20060166925
    Abstract: The invention concerns novel substitution derivatives of N6-benzyladenosine having anticancer, mitotic, immunosuppressive and antisenescent properties for plant, animal and human cells. This invention also relates to the methods of preparation of these N6-benzyladenosine derivatives and their use as drugs, cosmetic preparations and growth regulators comprising these derivatives as active compound and use of these derivatives for preparation of pharmaceutical compositions, in biotechnological processes, in cosmetics and in agriculture.
    Type: Application
    Filed: December 29, 2003
    Publication date: July 27, 2006
    Inventors: Karel Dolezal, Igor Popa, Marek Zatloukal, Rene Lenobel, Dana Hradecka, Borivoj Vojtesek, Stjepan Uldrijan, Petr Mlejnek, Stefaan Werbrouck, Miroslav Strnad