Patents by Inventor Borja Saez

Borja Saez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALDH3A2 INHIBITION AND FERROPTOSIS INDUCTION FOR CANCER THERAPY
    Publication number: 20230000896
    Abstract: Disclosed herein are methods and compositions for inhibiting Aldh3a2 expression and activity to improve leukemia outcomes. Aldh3a2 depletion results in iron-dependent oxidative cell death of leukemia cells while sparing normal hematopoiesis.
    Type: Application
    Filed: December 9, 2020
    Publication date: January 5, 2023
    Inventors: David T. Scadden, Rushdia Yusuf, Nick Van Gastel, Azeem S. Sharda, Borja Saez, Shrikanta Chattopadhyay, Vasanthi S. Viswanathan
  • Methods and compositions for mobilizing stem cells
    Patent number: 11116819
    Abstract: The present invention relates to methods and compositions for mobilizing hematopoietic stem cells and/or progenitor cells, and related methods of conditioning for engraftment of transplanted hematopoietic stem cells and/or progenitor cells, and methods of treating diseases requiring hematopoietic stem cell and/or progenitor cell transplantation.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: September 14, 2021
    Assignees: President and Fellows of Harvard College, The General Hospital Corporation
    Inventors: David T. Scadden, Borja Saez, Francesca Ferraro, Jonathan Hoggatt
  • METHODS AND COMPOSITIONS FOR MOBILIZING STEM CELLS
    Publication number: 20200268850
    Abstract: The present invention relates to methods and compositions for mobilizing hematopoietic stem cells and/or progenitor cells, and related methods of conditioning for engraftment of transplanted hematopoietic stem cells and/or progenitor cells, and methods of treating diseases requiring hematopoietic stem cell and/or progenitor cell transplantation.
    Type: Application
    Filed: April 15, 2020
    Publication date: August 27, 2020
    Inventors: David T. Scadden, Borja Saez, Francesca Ferraro, Jonathan Hoggatt
  • METHODS AND COMPOSITIONS FOR MOBILIZING STEM CELLS
    Publication number: 20160120947
    Abstract: The present invention relates to methods and compositions for mobilizing hematopoietic stem cells and/or progenitor cells, and related methods of conditioning for engraftment of transplanted hematopoietic stem cells and/or progenitor cells, and methods of treating diseases requiring hematopoietic stem cell and/or progenitor cell transplantation.
    Type: Application
    Filed: February 28, 2014
    Publication date: May 5, 2016
    Inventors: David T. Scadden, Borja Saez, Francesca Ferraro, Jonathan Hoggatt