Patents by Inventor Borut Zupancic

Borut Zupancic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine
    Patent number: 9493409
    Abstract: The present invention provides new intermediate compounds or formulae (III) and (IVa), and salts thereof, and their use in a new synthetic process for the production of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine (vortioxetine) an experimental drug under development for the treatment of depression and anxiety.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: November 15, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventor: Borut Zupancic
  • Synthesis of triazolopyrimidine compounds
    Patent number: 9469614
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: October 18, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Borut Zupancic, Nenad Maras, Damjan Sterk
  • Ticagrelor adducts with divalent metal salts
    Patent number: 9284320
    Abstract: The present invention relates to amorphous adducts of ticagrelor with divalent metal salts useful in the treatment or prevention of arterial thrombotic complications in patients with coronary artery, cerebrovascular or peripheral vascular disease.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: March 15, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventor: Borut Zupancic
  • New Process For The Synthesis Of 1-(2-((2,4-Dimethylphenyl)Thio)Phenyl)Piperazine
    Publication number: 20160060215
    Abstract: The present invention provides new intermediate compounds or formulae (III) and (IVa), and salts thereof, and their use in a new synthetic process for the production of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine (vortioxetine) an experimental drug under development for the treatment of depression and anxiety.
    Type: Application
    Filed: April 4, 2014
    Publication date: March 3, 2016
    Applicant: Lek Pharmaceuticals d.d.
    Inventor: Borut Zupancic
  • Synthesis of triazolopyrimidine compounds
    Patent number: 9221829
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of Ticagrelor (TCG).
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: December 29, 2015
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Nened Maras, Borut Zupancic
  • Ticagrelor Adducts With Divalent Metal Salts
    Publication number: 20150191475
    Abstract: The present invention relates to amorphous adducts of ticagrelor with divalent metal salts useful in the treatment or prevention of arterial thrombotic complications in patients with coronary artery, cerebrovascular or peripheral vascular disease.
    Type: Application
    Filed: July 3, 2013
    Publication date: July 9, 2015
    Applicant: Lek Pharmaceuticals d.d.
    Inventor: Borut Zupancic
  • Synthesis of Triazolopyrimidine Compounds
    Publication number: 20150005498
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of Ticagrelor (TCG).
    Type: Application
    Filed: September 14, 2012
    Publication date: January 1, 2015
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Nened Maras, Borut Zupancic
  • Synthesis of Triazolopyrimidine Compounds
    Publication number: 20140256747
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
    Type: Application
    Filed: October 26, 2012
    Publication date: September 11, 2014
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Borut Zupancic, Nenad Maras, Damjan Sterk