Abstract: The embodiments of the disclosure disclose a splitter, an LED display system, a method for configuring display screen and a device for configuring display screen. The splitter is applicable to an LED display screen, wherein the LED display screen includes a plurality of display units, each of the display units includes an assembly controller and an LED display assembly electrically connected to the assembly controller, and the LED display assembly includes a plurality of LED display pixels; and the splitter includes: a processor; a master interface electrically connected to the processor; and a plurality of loading interfaces electrically connected to the processor, wherein each of the loading interfaces is configured to load one of the display units or a plurality of cascaded display units.