Abstract: An unmanned vehicle includes a body, at least one power source coupled to the body, a flight propulsion system coupled to the at least one power source and configured to propel the unmanned vehicle through air, and a surface propulsion system coupled to the at least one power source and configured to propel the unmanned vehicle along a surface. The unmanned vehicle is configured to switch between a flight configuration in which the unmanned vehicle is propelled through air via the flight propulsion system, and a surface traverse configuration in which the unmanned vehicle is propelled along the surface via the surface propulsion system. In the surface traverse configuration, the surface propulsion system is configured to engage the surface and to maintain the body in a traversing position below the surface as the surface propulsion system propels the unmanned vehicle along the surface.

Abstract: The present invention relates to a novel antibody-based targeting drug—a single domain antibody energized fusion protein VH-LDP-AE with potent cancer cell killing activity, anti-angiogenic activity, and anti-cancer therapeutic efficacy, to a method for producing the same, and use thereof in manufacture of an anti-tumor medicament.