Patents by Inventor Boyd Goodson

Boyd Goodson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for creating hyperpolarization at microTesla magnetic fields
    Patent number: 11156684
    Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: October 26, 2021
    Assignees: Duke University, Vanderbilt University, Board of Trustees of Southern Illinois University
    Inventors: Warren S. Warren, Thomas Theis, Eduard Y. Chekmenev, Milton L. Truong, Aaron M. Coffey, Boyd Goodson, Fan Shi, Roman V. Shchepin
  • Method for creating hyperpolarization at microtesla magnetic fields
    Patent number: 11016152
    Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields. The spin polarization is hyperpolarization of isotopically enriched heteronuclei by using a catalyst and parahydrogen to create a complex using iridium and applying magnetic fields in the microtesia range to transfer the spin order from parahydrogen to the complex.
    Type: Grant
    Filed: May 12, 2018
    Date of Patent: May 25, 2021
    Assignees: Vanderbilt University, Duke University, The Board of Trustees of Southern Illinois University
    Inventors: Eduard Y. Chekmenev, Danila A. Barskiy, Roman V. Shchepin, Warren S. Warren, Thomas Theis, Boyd Goodson
  • METHOD FOR CREATING HYPERPOLARIZATION AT MICROTESLA MAGNETIC FIELDS
    Publication number: 20200132788
    Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields. The spin polarization is hyperpolarization of isotopically enriched heteronuclei by using a catalyst and parahydrogen to create a complex using iridium and applying magnetic fields in the microtesia range to transfer the spin order from parahydrogen to the complex.
    Type: Application
    Filed: May 12, 2018
    Publication date: April 30, 2020
    Inventors: Eduard Y. Chekmenev, Danila A. Barskiy, Roman V. Shchepin, Warren S. Warren, Thomas Theis, Boyd Goodson
  • PH-sensitive imaging agents
    Patent number: 9682157
    Abstract: Composition and method for surface-functionalized SPION-based agents. Such agents can provide highly pH-sensitive MRI contrast in tissue.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: June 20, 2017
    Assignee: BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY
    Inventors: Yong Gao, Boyd Goodson
  • METHOD FOR CREATING HYPERPOLARIZATION AT MICROTESLA MAGNETIC FIELDS
    Publication number: 20160169998
    Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields.
    Type: Application
    Filed: October 28, 2015
    Publication date: June 16, 2016
    Inventors: Warren S. Warren, Thomas Theis, Eduard Y. Chekmenev, Milton Y. Truong, Aaron M. Coffey, Boyd Goodson, Fan Shi, Roman V. Shchepin
  • PH-SENSITIVE IMAGING AGENTS
    Publication number: 20140127138
    Abstract: Composition and method for surface-functionalized SPION-based agents. Such agents can provide highly pH-sensitive MRI contrast in tissue.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 8, 2014
    Applicant: Board of Trustees of Southern Illinois University
    Inventors: Yong Gao, Boyd Goodson
  • Apparatus for preparing a solution of a hyperpolarized noble gas for NMR and MRI analysis
    Patent number: 7385395
    Abstract: The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
    Type: Grant
    Filed: September 13, 2004
    Date of Patent: June 10, 2008
    Assignee: Lawrence Berkeley National Laboratory
    Inventors: Alexander Pines, Thomas Budinger, Gil Navon, Yi-Qiao Song, Stephan Appelt, Angelo Bifone, Rebecca Taylor, Boyd Goodson, Roberto Seydoux, Toomas Room, Tanja Pietrass
  • Laminate structure with polycarbonate sheets and method of making
    Publication number: 20050241759
    Abstract: Disclosed is a decorative laminate structure having at least two sheets of polycarbonate and at least one decorative image layer there-between two sheets of polycarbonate, and a method of making the decorative laminate structure. Through heat and pressure the sheet layers and the decorative image layer are bonded together resulting in a decorative laminate structure of this invention. This product is intended for use primarily to produce decorative articles which include counter tops, table tops, cabinet doors, game boards, toys, panels for shower stalls, hot tubs, markerboards, indoor and outdoor signs, seamless vanity tops including sink, soap dish, back splash, flooring and others.
    Type: Application
    Filed: July 6, 2005
    Publication date: November 3, 2005
    Inventors: Raymond Goodson, Boyd Goodson
  • Laminate structure with polycarbonate sheets and method of making
    Publication number: 20050175832
    Abstract: Disclosed is a decorative laminate structure having at least two sheets of polycarbonate and at least one decorative image layer there-between two sheets of polycarbonate, and a method of making the decorative laminate structure. Through heat and pressure the sheet layers and the decorative image layer are bonded together resulting in a decorative laminate structure of this invention. This product is intended for use primarily to produce decorative articles which include counter tops, table tops, cabinet doors, game boards, toys, panels for shower stalls, hot tubs, markerboards, indoor and outdoor signs, seamless vanity tops including sink, soap dish, back splash, flooring and others.
    Type: Application
    Filed: June 18, 2003
    Publication date: August 11, 2005
    Inventors: Raymond Goodson, Boyd Goodson
  • Enhancement of NMR and MRI in the presence of hyperpolarized noble gases
    Publication number: 20050030026
    Abstract: The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
    Type: Application
    Filed: September 13, 2004
    Publication date: February 10, 2005
    Inventors: Alexander Pines, Thomas Budinger, Gil Navon, Yi-Qiao Song, Stephan Appelt, Angelo Bifone, Rebecca Taylor, Boyd Goodson, Roberto Seydoux, Toomas Room, Tanja Pietrass
  • Enhancement of NMR and MRI in the presence of hyperpolarized noble gases
    Patent number: 6818202
    Abstract: The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: November 16, 2004
    Assignee: The Regents of the University of California
    Inventors: Alexander Pines, Thomas Budinger, Gil Navon, Yi-Qiao Song, Stephan Appelt, Angelo Bifone, Rebecca Taylor, Boyd Goodson, Roberto Seydoux, Toomas Room, Tanja Pietrass
  • Enhancement of NMR and MRI in the presence of hyperpolarized noble gases
    Publication number: 20030017110
    Abstract: The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
    Type: Application
    Filed: June 5, 2002
    Publication date: January 23, 2003
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Alexander Pines, Thomas Budinger, Gil Navon, Yi-Qiao Song, Stephan Appelt, Angelo Bifone, Rebecca Taylor, Boyd Goodson, Roberto Seydoux, Toomas Room, Tanja Pietrass
  • Enhancement of NMR and MRI in the presence of hyperpolarized noble gases
    Patent number: 6426058
    Abstract: The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: July 30, 2002
    Assignee: The Regents of the University of California
    Inventors: Alexander Pines, Thomas Budinger, Gil Navon, Yi-Qiao Song, Stephan Appelt, Angelo Bifone, Rebecca Taylor, Boyd Goodson, Roberto Seydoux, Toomas Room, Tanja Pietrass
  • ENHANCEMENT OF NMR AND MRI IN THE PRESENCE OF HYPERPOLARIZED NOBLE GASES
    Publication number: 20020094317
    Abstract: The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.
    Type: Application
    Filed: March 28, 1997
    Publication date: July 18, 2002
    Inventors: ALEXANDER PINES, THOMAS BUDINGER, GIL NAVON, YI-QIAO SONG, STEPHAN APPELT, ANGELO BIFONE, REBECCA TAYLOR, BOYD GOODSON, ROBERTO SEYDOUX, TOOMAS ROOM, TANJA PIETRASS