Patents by Inventor Boyd L. Harrison

Boyd L. Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NMDA antagonists
    Patent number: 5606063
    Abstract: The present invention is directed to a new class of 4-sulfanimide-quinoline derivatives and to their use as NMDA antagonists.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 25, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Boyd L. Harrison, Bruce M. Baron, David M. Stemerick, Ian A. McDonald
  • Heterocycle substituted propenoic acid derivatives and pharmaceutical compositions thereof
    Patent number: 5563157
    Abstract: The present invention is new 3-(heterocyclic)-propenoic acid derivatives and pharmaceutical compositions thereof. These new 3-(heterocyclic)-propenoic acid derivatives are useful as NMDA antagonist.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: October 8, 1996
    Assignee: Hoechst Marion Roussel Inc.
    Inventors: Boyd L. Harrison, Philip L. Nyce, Robert A. Farr
  • 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof
    Patent number: 5519048
    Abstract: The present invention is new 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof. These new 3-indolyl-3-yl-prpopenoic acid derivatives are useful as NMDA antagonist.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: May 21, 1996
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Francesco G. Salituro, Bruce M. Baron, Boyd L. Harrison, Philip L. Nyce
  • Excitatory amino acid antagonists which are certain thienopyridives
    Patent number: 5112821
    Abstract: The present invention is directed to a new class of excitatory amino acid antagonists.
    Type: Grant
    Filed: February 14, 1991
    Date of Patent: May 12, 1992
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Boyd L. Harrison, Bruce M. Baron
  • Certain quinolines and thienopyridines as excitatory amino acid antagonists
    Patent number: 5026700
    Abstract: The present invention is directed to a new class of excitatory amino acid antagonists. The compounds contain quinoline or thieno pyridine moieties.
    Type: Grant
    Filed: March 21, 1990
    Date of Patent: June 25, 1991
    Assignee: Merrell Dow Pharmaceuticals
    Inventors: Boyd L. Harrison, Bruce M. Baron
  • Excitatory amino acid antagonists
    Patent number: 4960786
    Abstract: The present invention is directed to the discovery of a new use for a group of known 2-carboxylic indole derivatives. The compounds are excitatory amino acid antagonists.
    Type: Grant
    Filed: April 24, 1989
    Date of Patent: October 2, 1990
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Francesco G. Salituro, Boyd L. Harrison, Bruce M. Baron
  • Antifungal 2-anilinothiazolines
    Patent number: 4788209
    Abstract: Fungal infections of the skin and mucous membranes may be controlled by topical administration of a pharmaceutical composition comprising a N-(3- or 4-alkylphenyl)4,5-dihydro-2-thiazolamine.
    Type: Grant
    Filed: February 17, 1987
    Date of Patent: November 29, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Russell J. Baumann, Boyd L. Harrison
  • Anti-inflammatory agents and antiasthmatic agents
    Patent number: 4435420
    Abstract: N-(1,3-dithiolan-2-ylidene)-4-alkylanilines are useful as anti-inflammatory agents, as analgesic agents and as antiasthmatic agents. The compounds involved can be prepared by the reaction of an appropriate 4-alkylaniline with a methyl(1,3-dithiolan-2-ylidene)sulfonium salt or with carbon disulfide and ethylene dibromide in the presence of a base.
    Type: Grant
    Filed: April 12, 1982
    Date of Patent: March 6, 1984
    Assignee: Merrell Dow Pharmaceuticals
    Inventors: Boyd L. Harrison, Niall S. Doherty
  • 4-(Substituted alkyl)-N-(1,3-dithiolan-2-ylidene(aniline
    Patent number: 4391818
    Abstract: N-(1,3-dithiolan-2-ylidene)-4-alkylanilines having a hydroxy, alkoxy or alkanoyloxy substituent on the alkyl group are useful as anti-inflammatory agents, as analgesic agents and as antiasthmatic agents. The compounds involved can be prepared by the reaction of an appropriate 4-alkylaniline with a methyl(1,3-dithiolan-2-ylidene)sulfonium salt or with carbon disulfide and ethylene dibromide in the presence of a base.
    Type: Grant
    Filed: April 12, 1982
    Date of Patent: July 5, 1983
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Boyd L. Harrison, Niall S. Doherty
  • 7-(1,3-Dithiolan-2-imino)cephalosporanic acid derivatives
    Patent number: 4302581
    Abstract: Novel 7-(1,3-dithiolan-2-imino)cephalosporin derivatives are described which are particularly useful for their antibacterial properties.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: November 24, 1981
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini
  • 7-(1,3-Dithiolan-2-imino)-.DELTA..sup.2 -cephalosporanic acid derivatives
    Patent number: 4291160
    Abstract: Novel 7-(1,3-dithiolan-2-imino)-.DELTA..sup.2 -cephalosporanic acid derivatives are described which possess useful antibacterial properties.
    Type: Grant
    Filed: November 5, 1979
    Date of Patent: September 22, 1981
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini
  • 7-(1,3-Dithiolan-2-imino)-.DELTA..sup.2 -cephalosporanic acid derivatives
    Patent number: 4208516
    Abstract: Novel 7-(1,3-dithiolan-2-imino)-.DELTA..sup.2 -cephalosporanic acid derivatives are described which possess useful antibacterial properties.
    Type: Grant
    Filed: March 12, 1979
    Date of Patent: June 17, 1980
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini
  • 7-(1,3-Dithiolan-2-imino)cephalosporanic acid derivatives
    Patent number: 4206305
    Abstract: Novel 7-(1,3-dithiolan-2-imino)cephalosporin derivatives are described which are particularly useful for their antibacterial properties.
    Type: Grant
    Filed: March 12, 1979
    Date of Patent: June 3, 1980
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini
  • 6-(1,3-Dithiolan-2-imino)penicillanic acid derivatives
    Patent number: 4206119
    Abstract: Novel 6-(1,3-dithiolan-2-imino)penicillanic acid derivatives are described which are particularly useful for their antibacterial properties.
    Type: Grant
    Filed: March 12, 1979
    Date of Patent: June 3, 1980
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini
  • 7-[2-[.omega.-(1,3-Dit hiolan-2-imino)substituted]-acetylamino]cephalosporanic acid derivatives
    Patent number: 4172941
    Abstract: Novel 7-[2-[.omega.-(1,3-dithiolan-2-imino)substituted]-acetylamino]cephalospora nic acid derivatives are described having useful antibacterial activity.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: October 30, 1979
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini
  • .omega.-(1,3-Dithiolan-2-imino) substituted acetic acids
    Patent number: 4131683
    Abstract: .omega.-(1,3-Dithiolan-2-imino) substituted acetic acids are prepared useful as antibacterial agents, inhibitors of cholesterol and fatty acid synthesis, anti-inflammatory agents and as intermediates for cephalosporin antibiotics.
    Type: Grant
    Filed: May 12, 1978
    Date of Patent: December 26, 1978
    Assignee: Richardson-Merrell Inc.
    Inventors: Boyd L. Harrison, Joseph E. Dolfini