Patents by Inventor Boyko Traychev Kabakchiev

Boyko Traychev Kabakchiev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutically Triggering an Innate Immune Response in a Target Tissue
    Publication number: 20220236284
    Abstract: The invention provides therapeutic compositions that present an artificial repertoire of mammalian pattern recognition receptor (PRR) agonists, so that the pattern of PRR agonists recapitulates a distinct portion of a PRR agonist signature of a mammalian pathogen. The artificial repertoire of PRR agonists may be formulated together in a therapeutic vehicle for combined presentation to an innate immune cell resident in a target tissue in a mammalian host, and the vehicle adapted to deliver the PRR agonists to the target tissue, so as to modulate an immune response.
    Type: Application
    Filed: December 6, 2021
    Publication date: July 28, 2022
    Inventors: Harold David Gunn, David W. Mullins, Shirin Kalyan, Momir Bosiljcic, Monan Angela Zhang, Mark Bazett, Marcel Thalen, Dermot McGovern, Boyko Traychev Kabakchiev, Ho Pan Sham
  • Therapeutically triggering an innate immune response in a target tissue
    Patent number: 11226340
    Abstract: The invention provides therapeutic compositions that present an artificial repertoire of mammalian pattern recognition receptor (PRR) agonists, so that the pattern of PRR agonists recapitulates a distinct portion of a PRR agonist signature of a mammalian pathogen. The artificial repertoire of PRR agonists may be formulated together in a therapeutic vehicle for combined presentation to an innate immune cell resident in a target tissue in a mammalian host, and the vehicle adapted to deliver the PRR agonists to the target tissue, so as to modulate an immune response.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: January 18, 2022
    Assignee: Qu Biologics Inc.
    Inventors: Harold David Gunn, David W. Mullins, Shirin Kalyan, Momir Bosiljcic, Monan Angela Zhang, Mark Bazett, Marcel Thalen, Dermot McGovern, Boyko Traychev Kabakchiev, Ho Pan Sham
  • Therapeutically Triggering an Innate Immune Response in a Target Tissue
    Publication number: 20190134172
    Abstract: The invention provides therapeutic compositions that present an artificial repertoire of mammalian pattern recognition receptor (PRR) agonists, so that the pattern of PRR agonists recapitulates a distinct portion of a PRR agonist signature of a mammalian pathogen. The artificial repertoire of PRR agonists may be formulated together in a therapeutic vehicle for combined presentation to an innate immune cell resident in a target tissue in a mammalian host, and the vehicle adapted to deliver the PRR agonists to the target tissue, so as to modulate an immune response.
    Type: Application
    Filed: April 26, 2017
    Publication date: May 9, 2019
    Inventors: Harold David Gunn, David W. Mullins, Shirin Kalyan, Momir Bosiljcic, Monan Angela Zhang, Mark Bazett, Marcel Thalen, Dermot McGovern, Boyko Traychev Kabakchiev, Ho Pan Sham