Patents by Inventor Boyu HU

Boyu HU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11916561
    Abstract: An apparatus may include a first clock generator configured to receive an input clock signal, and generate two or more first-level clock signals of a track-and-hold circuit, a phase interpolator configured to generate an interpolated clock signals, wherein the interpolated clock signal is based on the two or more first-level clock signals, and a second clock generator configured to generate two or more second-level clock signals based on the interpolated clock signal, wherein the phase of the two or more second-level clock signals relative to the phase of a respective first-level clock signal is determined, at least in part, by the phase of the interpolated clock signal.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: February 27, 2024
    Assignee: AVAGO TECHNOLOGIES INTERNATIONAL SALES PTE. LIMITED
    Inventors: Boyu Hu, Chang Liu, Guansheng Li, Haitao Wang, Delong Cui, Jun Cao
  • Publication number: 20230365558
    Abstract: A series of tetrahydroisoquinoline derivatives and the crystal forms thereof. Specifically disclosed are a compound as represented by formula (VII), a crystal form thereof, and a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 18, 2021
    Publication date: November 16, 2023
    Inventors: Kevin X CHEN, Zuhao GUO, Yanxin YU, Boyu HU, Jingjing WANG, Zhaoguo CHEN, Cheng XIE, Jian XIONG, Yongbo FANG, Yingtao LIU, Jian LI, Shuhui CHEN
  • Publication number: 20230055321
    Abstract: Provided are a class of DNA-PK inhibitor, and specifically, a compound represented by formula (III) or a pharmaceutically acceptable salt thereof, and use thereof in the preparation of DNA-PK inhibitor-related drugs.
    Type: Application
    Filed: November 20, 2020
    Publication date: February 23, 2023
    Inventors: Kevin X CHEN, Shanghua XIA, Zhaoguo CHEN, Zuhao GUO, Yanxin YU, Kai ZHOU, Boyu HU, Li ZHANG, Fen JIANG, Jingjing WANG, Guoping HU, Jian LI, Shuhui CHEN
  • Publication number: 20230026616
    Abstract: A class of DNA-PK inhibitors, in particular a compound represented by formula (IV) or a pharmaceutically acceptable salt thereof, and an application thereof in the preparation of a drug relating to a DNA-PK inhibitor.
    Type: Application
    Filed: November 25, 2020
    Publication date: January 26, 2023
    Inventors: Kevin X CHEN, Shanghua XIA, Zhaoguo CHEN, Zuhao GUO, Yanxin YU, Kai ZHOU, Boyu HU, Li ZHANG, Fen JIANG, Jingjing WANG, Guoping HU, Jian LI, Shuhui CHEN
  • Patent number: 11466024
    Abstract: A bicyclic compound acting as a ROR? inhibitor. Provided are a compound of formula (I) or a pharmaceutically acceptable salt thereof, the compound having a structure as represented by formula (I-A) or formula (I-B). The provided compound of formula (I-A) or formula (I-B) or pharmaceutically acceptable salt thereof has good ROR? inhibitory activities, being expected to be used for treating diseases mediated by ROR? receptors in a mammal.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: October 11, 2022
    Assignees: Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Medshine Discovery Inc.
    Inventors: Kevin X Chen, Kai Zhou, Yanxin Yu, Boyu Hu, Linghui Wu, Xiaoyuan Chen, Jiangfeng Lin, Haomin Chen, Xiangjian Wang, Xiquan Zhang, Xin Tian, Hongjiang Xu
  • Publication number: 20220267310
    Abstract: Disclosed in the present invention are a compound as represented by formula (I), and an isomer or pharmaceutically acceptable salt thereof, and disclosed is an application thereof in preparing drugs for treating DNA-PK inhibitor-related diseases.
    Type: Application
    Filed: June 24, 2020
    Publication date: August 25, 2022
    Applicant: MEDSHINE DISCOVERY INC.
    Inventors: Kevin X Chen, Zhaoguo Chen, Li Zhang, Boyu Hu, Shuhui Chen
  • Publication number: 20220242851
    Abstract: The present invention relates to a crystal form and a salt of a compound serving as a Pan-HER tyrosine kinase inhibitor and a preparation method therefor, and also use thereof in the preparation of a medicament for treating solid tumors.
    Type: Application
    Filed: June 19, 2020
    Publication date: August 4, 2022
    Applicants: SHENZHEN JINRUI FOUNDATION BIOTECH CO., LTD, MEDSHINE DISCOVERY INC.
    Inventors: Kevin X. CHEN, Li ZHANG, Kai ZHOU, Yanxin YU, Boyu HU, Huiyu ZHANG
  • Patent number: 11377444
    Abstract: Disclosed are a series of pyridopyrimidine compounds and a use of same in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors, and specifically disclosed is a use of the compounds as shown in formula (IV), tautomers thereof or pharmaceutically acceptable salts thereof in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: July 5, 2022
    Assignee: MEDSHINE DISCOVERY INC.
    Inventors: Kevin X Chen, Zhaoguo Chen, Li Zhang, Yanxin Yu, Kai Zhou, Boyu Hu, Xiaofei Wang, Guoping Hu, Jian Li, Shuhui Chen
  • Publication number: 20220185825
    Abstract: Provided are a salt form and a crystal form of adenosine A2A receptor antagonist, and preparation method therefor. Also provided is an application of the salt form or crystal form in the preparation of a medicine for A2A receptor-related diseases, the maleate salt in the salt form has a structure of formula (I).
    Type: Application
    Filed: March 27, 2020
    Publication date: June 16, 2022
    Inventors: Kevin X CHEN, Kai ZHOU, Yanxin YU, Boyu HU, Li ZHANG, Zhaoguo CHEN
  • Patent number: 11312715
    Abstract: Disclosed are a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and an application of the compound or slat in preparation of drugs for treating diseases related to an A2A receptor.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: April 26, 2022
    Assignees: CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD., CSTONE PHARMACEUTICALS (SHANGHAI) CO., LTD., CSTONE PHARMACEUTICALS
    Inventors: Kevin X Chen, Kai Zhou, Boyu Hu, Minliang Xiao, Shuhui Chen
  • Patent number: 11174270
    Abstract: A crystal form A of a 3,4-dihydrothieno[3,2-d]pyrimidine compound (1), a preparation method therefor and an application thereof in the preparation of an anti-human cytomegalovirus (HCMV) drug.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: November 16, 2021
    Assignee: Phaeno Therapeutics Co., Ltd.
    Inventors: Jian Xiong, Jingjing Wang, Boyu Hu, Haizhong Tan, Kevin X. Chen, Jian Li, Shuhui Chen
  • Publication number: 20210323979
    Abstract: The present invention relates to a group of pyrrolo[2,1-f][1,2,4]triazine derivatives serving as selective HER2 inhibitors and an application thereof in the preparation of a drug that serves as an HER2 inhibitor. Specifically, the present invention relates to a compound represented by formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 8, 2019
    Publication date: October 21, 2021
    Applicant: MEDSHINE DISCOVERY INC.
    Inventors: Kevin X CHEN, Fen JIANG, Xinde CHEN, Li ZHANG, Zhaoguo CHEN, Yanxin YU, Kai ZHOU, Boyu HU, Cheng XIE, Shuhui CHEN
  • Publication number: 20210078958
    Abstract: The present invention relates to a series of quinazoline compounds, especially compounds as represented by formula (I), isomers thereof or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and use thereof as Pan-HER tyrosine kinase inhibitors.
    Type: Application
    Filed: December 19, 2018
    Publication date: March 18, 2021
    Applicant: Medshine Discovery Inc.
    Inventors: Kevin X. CHEN, XiaWei WEI, Li ZHANG, Yanxin YU, Kai ZHOU, Boyu HU, Zhaoguo CHEN, Huiyu ZHANG, Shuhui CHEN
  • Publication number: 20210024538
    Abstract: A crystal form A of a 3,4-dihydrothieno[3,2-d]pyrimidine compound (1), a preparation method therefor and an application thereof in the preparation of an anti-human cytomegalovirus (HCMV) drug.
    Type: Application
    Filed: January 29, 2019
    Publication date: January 28, 2021
    Inventors: Jian Xiong, Jingjing WANG, Boyu HU, Haizhong TAN, KEVIN X CHEN, jIAN li, Shuhui CHEN
  • Publication number: 20200339568
    Abstract: Disclosed are a series of pyridopyrimidine compounds and a use of same in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors, and specifically disclosed is a use of the compounds as shown in formula (IV), tautomers thereof or pharmaceutically acceptable salts thereof in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors.
    Type: Application
    Filed: November 2, 2018
    Publication date: October 29, 2020
    Inventors: Kevin X CHEN, Zhaoguo CHEN, Li ZHANG, Yanxin YU, Kai ZHOU, Boyu HU, Xiaofei WANG, Guoping HU, Jian LI, Shuhui CHEN
  • Patent number: 10738051
    Abstract: Disclosed in the present invention is a type of novel ?-lactamase inhibitors, and specifically disclosed are a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: August 11, 2020
    Assignee: QILU PHARMACEUTICAL CO., LTD.
    Inventors: Boyu Hu, Charles Z. Ding, Zhigang Huang, Ruibin Lin, Minliang Xiao, Jinsheng Xie, Shuhui Chen, Cheng Li
  • Publication number: 20200239465
    Abstract: Disclosed are a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and an application of the compound or slat in preparation of drugs for treating diseases related to an A2A receptor.
    Type: Application
    Filed: September 27, 2018
    Publication date: July 30, 2020
    Inventors: Kevin X CHEN, Kai ZHOU, Boyu HU, Minliang XIAO, Shuhui CHEN
  • Publication number: 20200231597
    Abstract: A bicyclic compound acting as a ROR? inhibitor. Provided are a compound of formula (I) or a pharmaceutically acceptable salt thereof, the compound having a structure as represented by formula (I-A) or formula (I-B). The provided compound of formula (I-A) or formula (I-B) or pharmaceutically acceptable salt thereof has good ROR? inhibitory activities, being expected to be used for treating diseases mediated by ROR? receptors in a mammal.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 23, 2020
    Applicants: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., MEDSHINE DISCOVERY INC.
    Inventors: Kevin X CHEN, Kai ZHOU, Yanxin YU, Boyu HU, Linghui WU, Xiaoyuan CHEN, Jiangfeng LIN, Haomin CHEN, Xiangjian WANG, Xiquan ZHANG, Xin TIAN, Hongjiang XU
  • Publication number: 20200010467
    Abstract: Disclosed in the present invention is a type of novel ?-lactamase inhibitors, and specifically disclosed are a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 2, 2017
    Publication date: January 9, 2020
    Applicant: MEDSHINE DISCOVERY INC.
    Inventors: Boyu HU, Charles Z. DING, Zhigang HUANG, Ruibin LIN, Minliang XIAO, Jinsheng XIE, Shuhui CHEN, Cheng LI