Patents by Inventor Bráulia Costa Caetano

Bráulia Costa Caetano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180271965
    Abstract: The present invention concerns to recombinant influenza viruses and modified Vaccinia Ankara viruses (MVA), and to a process for construction of recombinant influenza viruses and modified vaccinia Ankara viruses (MVA) with genes that encode for the T. gondii parasite SAGI (MVA) and SAG2 (MVA and influenza) proteins, by means of a homologous recombination technique between two transfer vectors (for construction of MVA virus) and reverse genetics (for construction of influenza virus). Additionally, the present invention describes a vaccine composition using recombinant influenza viruses and modified vaccinia Ankara viruses (MVA), or recombinant adenoviruses and modified vaccinia Ankara viruses (MVA), for immunization against infections caused by the T. gondii parasite.
    Type: Application
    Filed: February 28, 2018
    Publication date: September 27, 2018
    Inventors: Ricardo Tostes GAZZINELLI, Rafael Polidoro Alves BARBOSA, Braulia Costa CAETANO, Alexandre de Magalhaes Vieira MACHADO, Oscar BRUNA-ROMERO, Flavio Fonseca GUIMARAES, Erica Araujo MENDES
  • Patent number: 9937251
    Abstract: The present invention concerns to recombinant influenza viruses and modified Vaccinia Ankara viruses (MVA), and to a process for construction of recombinant influenza viruses and modified vaccinia Ankara viruses (MVA) with genes that encode for the T. gondii parasite SAGI (MVA) and SAG2 (MVA and influenza) proteins, by means of a homologous recombination technique between two transfer vectors (for construction of MVA virus) and reverse genetics (for construction of influenza virus). Additionally, the present invention describes a vaccine composition using recombinant influenza viruses and modified vaccinia Ankara viruses (MVA), or recombinant adenoviruses and modified vaccinia Ankara viruses (MVA), for immunization against infections caused by the T. gondii parasite.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: April 10, 2018
    Assignee: FUNDACAO OSWALDO CRUZ
    Inventors: Ricardo Tostes Gazzinelli, Rafael Polidoro Alves Barbosa, Braulia Costa Caetano, Alexandre de Magalhaes Vieira Machado, Oscar Bruna-Romero, Flavio Fonseca Guimaraes, Erica Araujo Mendes
  • Publication number: 20110045016
    Abstract: The present invention concerns to recombinant influenza viruses and modified Vaccinia Ankara viruses (MVA), and to a process for construction of recombinant influenza viruses and modified vaccinia Ankara viruses (MVA) with genes that encode for the T. gondii parasite SAGI (MVA) and SAG2 (MVA and influenza) proteins, by means of a homologous recombination technique between two transfer vectors (for construction of MVA virus) and reverse genetics (for construction of influenza virus). Additionally, the present invention describes a vaccine composition using recombinant influenza viruses and modified vaccinia Ankara viruses (MVA), or recombinant adenoviruses and modified vaccinia Ankara viruses (MVA), for immunization against infections caused by the T. gondii parasite.
    Type: Application
    Filed: December 22, 2008
    Publication date: February 24, 2011
    Applicant: FUNDACAO OSWALDO CRUZ
    Inventors: Ricardo Tostes Gazzinelli, Rafael Polidoro Alves Barbosa, Braulia Costa Caetano, Alexandre de Magalhaes Vieira Machado, Oscar Bruna-Romero, Flavio Fonseca Guimaraes, Erica Araujo Mendes
  • Publication number: 20090252760
    Abstract: This invention refers to the construction of recombinant adenovirus with genes that codify for T. gondii SAG1, SAG2 and SAG3, through a homologue recombination technique between two vectors. A first vector that serves as transference vector of genes and a second vector that bears the adenoviral receptor genome of these genes. The invention is also related to the use of recombinant adenovirus in a vaccine composition to obtain the immunization against infections caused by T. gondii parasite.
    Type: Application
    Filed: November 1, 2006
    Publication date: October 8, 2009
    Inventors: Ricardo Tostes Gazzinelli, Oscar Bruna-Romero, Bráulia Costa Caetano