Patents by Inventor Brad A. Acker

Brad A. Acker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis-arylsulfones
    Publication number: 20040029865
    Abstract: The present invention provides pharmaceutically active compounds useful for the treatment of diseases or disorders of the central nervous system.
    Type: Application
    Filed: May 14, 2003
    Publication date: February 12, 2004
    Inventors: Brad A. Acker, Robert Shih-Liang Chao, Michael Hawley
  • Substituted-aryl compounds for treatment of disease
    Publication number: 20030236279
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 10, 2003
    Publication date: December 25, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Jason K. Myers, Vincent E. Groppi
  • Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease
    Publication number: 20030236264
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 14, 2003
    Publication date: December 25, 2003
    Inventors: Bruce N. Rogers, David W. Piotrowski, Daniel Patrick Walker, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka, Vincent E. Groppi
  • Azabicyclic compounds for the treatment of disease
    Publication number: 20030236270
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 14, 2003
    Publication date: December 25, 2003
    Inventors: Eric Jon Jacobsen, Jason K. Myers, Daniel Patrick Walker, Donn G. Wishka, Steven Charles Reitz, David W. Piotrowski, Brad A. Acker, Vincent E. Groppi
  • Azabicyclic compounds for the treatment of disease
    Publication number: 20030232853
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 13, 2003
    Publication date: December 18, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Vincent E. Groppi
  • Substituted azepino[4,5b]indoline derivatives
    Publication number: 20030225058
    Abstract: The invention provides compounds of Formula (I): 1
    Type: Application
    Filed: March 20, 2003
    Publication date: December 4, 2003
    Applicant: Pharmacia & UpJohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-Min Fu, Eric Jon Jacobsen, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier
  • Substituted azepino[4,5b]indole derivatives
    Publication number: 20030220321
    Abstract: Disclosed are compounds of Formula (I): 1
    Type: Application
    Filed: March 20, 2003
    Publication date: November 27, 2003
    Applicant: Pharmacia & UpJohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-Min Fu, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier, Eric Jon Jacobsen
  • Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
    Publication number: 20030207913
    Abstract: The invention provides compounds of Formula I:
    Type: Application
    Filed: November 6, 2002
    Publication date: November 6, 2003
    Inventors: David W. Piotrowski, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, Alice L. Bodnar, Vincent E. Groppi, Daniel Patrick Walker, Brad A. Acker
  • N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
    Publication number: 20030176702
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: October 17, 2002
    Publication date: September 18, 2003
    Inventors: Daniel Patrick Walker, Eric Jon Jacobsen, David W. Piotrowski, Brad A. Acker, Donn G. Wishka, Jeffrey W. Corbett, Mark R. Rauckhorst, Vincent E. Groppi
  • Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease
    Publication number: 20030153595
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: October 1, 2002
    Publication date: August 14, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka, Steven Charles Reitz, Vincent E. Groppi
  • Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
    Publication number: 20030130305
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: November 1, 2002
    Publication date: July 10, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Vincent E. Groppi
  • Substituted azepino[4,5b]indoline derivatives
    Patent number: 6586421
    Abstract: The invention provides compounds of Formula (I): wherein R1-R4, p and q have any of the values described in the specification, as well as pharmaceutical salts thereof, and pharmaceutical compositions containing such compounds or salts. The compounds and salts are 5-HT ligands and are useful for treating diseases, disorders, and/or conditions in a mammal wherein activity of a 5-HT receptor is implicated. The compounds and salts are particularly useful for treating diseases of the central nervous system.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: July 1, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, Eric Jon Jacobsen, William W. McWhorter, Jr., Jeanette K. Morris, Donald Joseph Rogier
  • Substituted azepino[4,5b]indole derivatives
    Patent number: 6583135
    Abstract: Disclosed are compounds of Formula (I): wherein R1-R4, p and q have any of the values described in the specification, as well as pharmaceutical salts thereof, and pharmaceutical compositions containing such compounds or salts. The compounds and salts are 5-HT ligands and are useful for treating diseases, disorders, and/or conditions in a mammal wherein activity of a 5-HT receptor is implicated. The compounds and salts are particularly useful for treating diseases of the central nervous system.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: June 24, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, William W. McWhorter, Jr., Jeanette K. Morris, Donald Joseph Rogier, Eric Jon Jacobsen
  • Tetracyclic azepinoindole compounds
    Publication number: 20020198190
    Abstract: The present invention provides compounds of formula I: 1
    Type: Application
    Filed: June 17, 2002
    Publication date: December 26, 2002
    Applicant: PHARMACIA & UPJOHN COMPANY
    Inventors: Jackson B. Hester, Bruce N. Rogers, Eric Jon Jacobsen, Michael D. Ennis, Brad A. Acker, Susan L. Vander Velde, Kristine E. Frank
  • (5R)-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline-2(1H)-thione
    Publication number: 20020137763
    Abstract: The present invention is a novel pharmaceutical agent, (5R)-5-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline-2(1H)-thione 1
    Type: Application
    Filed: April 19, 2001
    Publication date: September 26, 2002
    Inventors: Brad A. Acker, Richard Frederick Heier, Alan Q. Jin, Malcolm Wilson Moon
  • Substituted azepino[4,5b]indole derivatives
    Publication number: 20020107278
    Abstract: Disclosed are compounds of Formula (I): 1
    Type: Application
    Filed: September 20, 2001
    Publication date: August 8, 2002
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier, Eric Jon Jacobsen
  • Substituted azepino[4,5b] indoline derivatives
    Publication number: 20020077318
    Abstract: The invention provides compounds of Formula (I): 1
    Type: Application
    Filed: September 20, 2001
    Publication date: June 20, 2002
    Inventors: Kristine E. Frank, Brad A. Acker, Michael D. Ennis, Jed F. Fisher, Jian-min Fu, Eric Jon Jacobsen, William W. McWhorter, Jeanette K. Morris, Donald Joseph Rogier
  • Tetracyclic azepinoindole compounds
    Patent number: 6407092
    Abstract: The present invention provides compounds of formula I: wherein R1, R2, X and Y have any of the values defined in the specification, as well as pharmaceutical compositions comprising the compounds. The invention also provides therapeutic methods as well as processes and intermediates useful for preparing compounds of formula (I).
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: June 18, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jackson B. Hester, Bruce N. Rogers, Eric Jon Jacobsen, Michael D. Ennis, Brad A. Acker, Susan L. Vander Velde, Kristine E. Frank