Abstract: A cap for medical connectors that absorbs deactivates and isolates hazardous fluid residues on the ends of medical connectors after administration of hazardous fluids.

Abstract: An interlocking medical connector configured to linearly drive a deliver needle perpendicularly through one or more septa by using a rotational moment to advance the needle without twisting. A non-rotatable junction and spinning collar that drives the male and female connectors together without needle twisting. A locking mechanism that requires an intentional motion by a user to disconnect, thereby reducing the risk of inadvertent disconnection. Additional absorbent layers to capture fluid that may escape the fluid pathway. And corresponding protective locking connector caps with an absorbent component that isolates, absorbs, and deactivates hazardous fluid residues on the connectors.