Abstract: The present disclosure is generally related to beverage containers, including cannabinoid and/or alkaloid-infused beverage containers, and associated devices, systems, and methods. In at least some embodiments, a beverage container can include one or more container walls forming the sides and/or bottom of the container, a conditioning component configured to releasably contain an active ingredient and to release at least a portion of the active ingredient into the container, and a lid which may be sealably attached to the container wall to create a sealed container. When a liquid is inserted into the beverage container and the lid is sealed to the container wall, the active ingredient can be held separate from the liquid by the conditioning component unless or until the conditioning component is activated/actuated to cause the active ingredient to mix with the liquid and create a beverage infused with the active ingredient.

Abstract: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.

Abstract: A method for dispensing opioids using a dispensing container in an anti-addiction pain-modulating regimen includes generating a dosage scheme for dispensing an opioid compound using the dispensing container including a controller programmable according to the dosage scheme and locked compartments storing the opioid compound. The dosage scheme includes a first dosage scheme for an opioid compound and a first dosage scheme for a cannabinoid compound to be administered to the patient concurrently over a period of time. The method includes sending the dosage scheme for operating the dispensing container. The controller stores one or more authentication programs and is programmed to authenticate the patient using the one or more authentication programs, and in response to authenticating the patient, unlock one or more of the compartments to allow the patient to access to a dosage of the opioid compound held in the one or more compartments according to the dosage scheme.

Abstract: The current disclosure provides tryptamine analogues including tryptamine analogues having a boron moiety. Boron is present in at least some of these tryptamine analogues. Uses of the tryptamine analogues of the current disclosure include uses in medical treatment, such as treatment for cancer, brain cancer, and use as a psychoactive treatment agent.

Abstract: The present disclosure provides a pharmaceutical composition for multi-stage release of psychoactive substances including cannabinoids. The pharmaceutical composition comprises two or more staged compositions having different release profiles or different release time such that the one or more active agents in each of the two or more staged compositions are released into the subject's blood stream at different time points.

Abstract: A method for reducing opioids in a pain-modulating regimen of a patient includes generating a dosage scheme for the patient based on parameters associated with the patient's health condition. The dosage scheme includes a first dosage scheme for an opioid compound and a first dosage scheme for a cannabinoid compound to be administered to the patient concurrently. The first dosage scheme for the opioid compound includes a first plurality of dosages with a decreasing amount of an active ingredient in the opioid compound over a period of time. The method also includes determining an addiction risk score for the patient based on the dosage scheme and determining whether to adjust the dosage scheme based on the addiction risk score for the patient. In response to determining to adjust the dosage scheme, the method includes generating an adjusted dosage scheme based on the addiction risk score indicators.

Abstract: The present disclosure is generally related to beverage containers, including cannabinoid and/or alkaloid-infused beverage containers, and associated devices, systems, and methods. In at least some embodiments, a beverage container can include one or more container walls forming the sides and/or bottom of the container, a conditioning component configured to releasably contain an active ingredient and to release at least a portion of the active ingredient into the container, and a lid which may be sealably attached to the container wall to create a sealed container. When a liquid is inserted into the beverage container and the lid is sealed to the container wall, the active ingredient can be held separate from the liquid by the conditioning component unless or until the conditioning component is activated/actuated to cause the active ingredient to mix with the liquid and create a beverage infused with the active ingredient.

Abstract: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.

Abstract: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.

Abstract: Described herein are systems and methods for automatically administering a psychoactive substance to a user based on detection of an event or condition during sleep. The systems and methods can be used to promote wellness in personal and research settings, and to facilitate brain-computer interface training, among other beneficial uses.

Abstract: The present disclosure provides a pharmaceutical composition for multi-stage release of psychoactive substances including cannabinoids. The pharmaceutical composition comprises two or more staged compositions having different release profiles or different release time such that the one or more active agents in each of the two or more staged compositions are released into the subject's blood stream at different time points.

Abstract: The present disclosure is generally related to beverage containers, including cannabinoid and/or alkaloid-infused beverage containers, and associated devices, systems, and methods. In at least some embodiments, a beverage container can include one or more container walls forming the sides and/or bottom of the container, a conditioning component configured to releasably contain an active ingredient and to release at least a portion of the active ingredient into the container, and a lid which may be sealably attached to the container wall to create a sealed container. When a liquid is inserted into the beverage container and the lid is sealed to the container wall, the active ingredient can be held separate from the liquid by the conditioning component unless or until the conditioning component is activated/actuated to cause the active ingredient to mix with the liquid and create a beverage infused with the active ingredient.