Patents by Inventor Brad H. Nelson

Brad H. Nelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor associated antigens and methods of using the same
    Patent number: 7214498
    Abstract: The present invention provides methods and compositions for the diagnosis of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis of autoimmune disease.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: May 8, 2007
    Assignee: Benaroya Research Institute at Virginia Mason
    Inventors: Brad H. Nelson, Bradley C. Stone
  • Chimeric cytokine receptors in lymphocytes
    Patent number: 5747292
    Abstract: Recombinant polynucleotides are provided that encode chimeric cytokine receptors. The chimeric receptor is comprised of an extracellular domain derived from cytokine receptor A-R that binds cytokine A, used to a transmembrane and cytoplasmic domain derived from cytokine receptor B-R that binds cytokine B. When the chimeric receptor is expressed in a lymphocyte it lessens the growth dependency of the lymphocyte on cytokine B in the presence of cytokine A.
    Type: Grant
    Filed: May 31, 1994
    Date of Patent: May 5, 1998
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Philip D. Greenberg, Brad H. Nelson