Patents by Inventor Brad M. Cox

Brad M. Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10662446
    Abstract: Disclosed herein are new strains of Propionibacterium and methods for the biosynthetic production of propionic acid.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: May 26, 2020
    Assignee: The University of Queensland
    Inventors: Carlos H. Luna-Flores, Lars K. Nielsen, Esteban Marcellin, Christopher C. Stowers, Bianca F. Martins, Brad M. Cox
  • Publication number: 20190071697
    Abstract: Disclosed herein are new strains of Propionibacterium and methods for the biosynthetic production of propionic acid.
    Type: Application
    Filed: September 29, 2016
    Publication date: March 7, 2019
    Inventors: Carlos H. LUNA-FLORES, Lars K. NIELSEN, Esteban MARCELLIN, Christopher C. STOWERS, Bianca F. MARTINS, Brad M. COX
  • Publication number: 20180200314
    Abstract: A composition includes a Euglena whole cell biomass and cellular components, including beta-1,3-glucan as at least about 90 percent linear, unbranched beta-1,3-glucan polysaccharide polymers having an average molecular weight of 1.2 to 580 kilodaltons (kDa) and beta-glucan polymer chains having a polymer length of about 7.0 to 3,400 glucose monomers. Residual media remains from a heterotrophic fermentation process that produced the Euglena biomass. The composition may be in different delivery forms and include added immune response inducing components.
    Type: Application
    Filed: February 19, 2018
    Publication date: July 19, 2018
    Inventors: Brad M. Cox, Derek E. Jamrog
  • Publication number: 20180169161
    Abstract: A composition includes a Euglena biomass lysate having an average particle size of about 2.0 to 500 micrometers and cellular components, including beta-1,3-glucan as at least about 90 percent linear, unbranched beta-1,3-glucan polysaccharide polymers having an average molecular weight of 1.2 to 580 kilodaltons (kDa) and beta-glucan polymer chains having a polymer length of about 7.0 to 3,400 glucose monomers. Residual media remains from a heterotrophic fermentation process that produced a Euglena biomass and the Euglena lysate. Vitamin C is added in an example, and the weight ratio of the beta-1,3-glucan to the added vitamin C is in the ratio of 1:10 to 1:1 and may be in different delivery forms. The composition may include other added immune response inducing components.
    Type: Application
    Filed: February 19, 2018
    Publication date: June 21, 2018
    Inventors: Brad M. COX, Derek E. JAMROG
  • Publication number: 20180168190
    Abstract: An animal feed composition includes a feed component made from corn, soy, corn or soy derivatives or byproducts, or grains and an added whole cell Euglena biomass, including beta-1,3-glucan having at least about 90 percent linear, unbranched beta-1,3-glucan polysaccharide polymers with an average molecular weight of about 1.2 to 580 kilodaltons (kDa). Beta-glucan polymer chains have a polymer length of about 7.0 to 3,400 glucose monomers. The whole cell Euglena biomass has at least 30 percent beta-1,3-glucan and residual media remaining from a heterotrophic fermentation process and is about 0.0001 to 0.0124 percent of the composition. It is possible to add a Euglena lysate.
    Type: Application
    Filed: February 19, 2018
    Publication date: June 21, 2018
    Inventors: Brad M. COX, Derek E. JAMROG
  • Patent number: 9901606
    Abstract: A composition includes a Euglena lysate and cellular components and residual media remaining from a fermentation process that produced a Euglena biomass and the Euglena lysate. The cellular components may include one or more beta-glucan polymer chains having a molecular weight of 1.2 to 580 kilodaltons (kDa).
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: February 27, 2018
    Assignee: ALGAEON, INC.
    Inventors: Brad M. Cox, Derek E. Jamrog, Kip R. Zurcher
  • Publication number: 20170356020
    Abstract: A method for producing a purified beta-1,3-glucan includes growing a biomass from genus Euglena organism and dewatering the grown biomass. The biomass is lysed to form a lysed biomass, which is washed and dewatered to produce a beta-1,3-glucan. The beta-1,3-glucan is dried to produce the purified beta-1,3-glucan.
    Type: Application
    Filed: June 9, 2016
    Publication date: December 14, 2017
    Inventors: Derek E. JAMROG, Brad M. COX, Kip R. ZURCHER
  • Publication number: 20170354699
    Abstract: A composition includes a Euglena lysate and cellular components and residual media remaining from a fermentation process that produced a Euglena biomass and the Euglena lysate. The cellular components may include one or more beta-glucan polymer chains having a molecular weight of 1.2 to 580 kilodaltons (kDa).
    Type: Application
    Filed: June 9, 2016
    Publication date: December 14, 2017
    Inventors: Brad M. COX, Derek E. JAMROG, Kip R. ZURCHER
  • Publication number: 20170354698
    Abstract: A method for producing a Euglena lysate includes growing a biomass from genus Euglena organisms, dewatering the grown biomass, lysing the biomass, and drying the lysed biomass to form a Euglena lysate.
    Type: Application
    Filed: June 9, 2016
    Publication date: December 14, 2017
    Inventors: Derek E. JAMROG, Brad M. Cox, Kip R. Zurcher
  • Patent number: 9834797
    Abstract: A process to prepare propionic acid comprises preparing a fermentation broth of water; at least 30 weight percent hydrolyzed corn mash solids, hydrolyzed sugar cane mash solids, or a combination thereof, based on the combined weight of the fermentation broth as a whole; and propionibacteria; without including the typical, frequently very costly supplementation with vitamin and mineral packages. Surprisingly, these mash solids, which must often be disposed of following syrup production, are capable of supplying the nitrogen, micronutrients, vitamins and minerals known to be needed for propionibacteria fermentation, making their sole or significant use as fermentation mediums far more economical and therefore desirable than other fermentation mediums which require supplementation.
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: December 5, 2017
    Assignee: Dow Global Technologies LLC
    Inventors: Christopher C. Stowers, Brandon A. Rodriguez, Brad M. Cox
  • Publication number: 20160017384
    Abstract: A process to prepare propionic acid comprises preparing a fermentation broth of water; at least 30 weight percent hydrolyzed corn mash solids, hydrolyzed sugar cane mash solids, or a combination thereof, based on the combined weight of the fermentation broth as a whole; and propionibacteria; without including the typical, frequently very costly supplementation with vitamin and mineral packages. Surprisingly, these mash solids, which must often be disposed of following syrup production, are capable of supplying the nitrogen, micronutrients, vitamins and minerals known to be needed for propionibacteria fermentation, making their sole or significant use as fermentation mediums far more economical and therefore desirable than other fermentation mediums which require supplementation.
    Type: Application
    Filed: February 17, 2014
    Publication date: January 21, 2016
    Applicant: Dow Global Technologies LLC
    Inventors: Christopher C. Stowers, Brandon A. Rodriguez, Brad M. Cox
  • Publication number: 20100285540
    Abstract: A process for producing (R)-?-arylalanines is described. The process converts (S)-?-arylalanine to (R)-?-arylalanine using phenylalanine aminomutase and amino acid racemase. The (R)-?-arylalanine product can be used to form pharmaceutically useful drugs. Also disclosed are DNA sequences encloding phenylalanine aminomutase and amino acid racemase enzymes, sequences for PCR primers of the DNA sequences, and sequences for expressed aminomutase and amino acid racemase enzymes.
    Type: Application
    Filed: April 30, 2010
    Publication date: November 11, 2010
    Applicant: Board of Trustees of Michigan State University
    Inventors: Kevin D. Walker, Brad M. Cox