Abstract: Various embodiments of a sheath device and related methods are described herein. In some embodiments, the sheath device can include a sheath hub and a sheath body extending from the sheath hub. The sheath body can include an inner passageway and a proximal section having a first length and a first flexibility along the first length. The sheath body can further include a distal section having a second length and a second flexibility along the second length, and the second flexibility can be greater than the first flexibility. The sheath body can further include an atraumatic tip positioned at a distal end of the sheath body, and the atraumatic tip can include a rounded distal end.

Abstract: System and methods are configured for accessing an artery such as a carotid artery. The system comprising a sheath stopper positioned on an exterior of a distal section of an arterial access sheath such that a portion of the distal section of the sheath is covered by the sheath stopper and a portion of the distal section of the sheath is exposed,. The sheath stopper is configured to limit insertion of the sheath into an artery to the exposed portion wherein a length of the exposed portion is adjustable.

Abstract: A pressure relief device for use in a percutaneous procedure, the device comprising a tube having a distal opening into an internal lumen and a proximal opening from the internal lumen, a length of the tube sized to position the distal opening near a closed arteriotomy in a vessel and the proximal opening remains external to a patient's skin. Related devices, kits, and methods are provided.

Abstract: Arterial closure devices as well as methods for making using arterial closure devices are disclosed. An example arterial closure device may include a proximal gasket configured to be positioned on a first side of a blood vessel wall. The arterial closure device may include a distal footplate configured to be positioned on a second side of the blood vessel wall opposite the proximal gasket. The arterial closure device may include a seal configured to be positioned on the first side of the blood vessel wall between the proximal gasket and the blood vessel wall. A tether may be coupled to at least the proximal gasket and the distal footplate. A securement element may be disposed on the tether. The securement element may be configured to secure the proximal gasket and the seal against the first side of the blood vessel wall.

Abstract: Disclosed are various embodiments and related methods of an arteriotomy formation system that can include a center puncturing device and an arteriotomy formation device. The center puncturing device can include a puncturing element that forms a puncture along a wall of a first vessel at a position central to a conduit passageway of a conduit. The arteriotomy formation device can include a tissue fixation element, a tissue capturing element, and a tissue cutting element. The arteriotomy formation device can form an arteriotomy along the first vessel such that the arteriotomy is centered relative to the conduit passageway.

Abstract: Various embodiments and related methods of a telescoping vascular sheath are disclosed. The telescoping vascular sheath can include a plurality of sheath segments each having a tapered distal section and a proximal section. Each tapered distal section can include a distal opening surface and each proximal section can include an outer proximal surface. Each sheath segment of the plurality of sheath segments can be slidably engaged with at least one adjacent sheath segment along one or more of the distal opening surfaces and the outer proximal surface. The telescoping vascular sheath can also include a working passageway extending through the plurality of sheath segments and along a longitudinal axis of the telescoping vascular sheath. The working passageway can provide access to an inner lumen of the vessel. In some embodiments, a blood flow system is disclosed.

Abstract: A system is used to access and treat a carotid artery. The system includes an arterial access device that receives blood flow from the common carotid artery via a distal region of the arterial access device. A shunt fluidly connects to the arterial access device and defines a blood flow pathway for blood to flow from the arterial access device to a return site. A flow control assembly assists blood flow through the shunt and includes a pump having at least one roller that interacts with the tubing of the shunt to pump blood through the shunt toward the return site.

Abstract: Arterial access sheaths for delivering a treatment, such as a transcatheter aortic valve treatment, having markers configured to illustrate orientation of the distal end region of the sheath. Related systems, devices, and methods are provided.

Abstract: A pressure relief device for use in a percutaneous procedure, the device comprising a tube having a distal opening into an internal lumen and a proximal opening from the internal lumen, a length of the tube sized to position the distal opening near a closed arteriotomy in a vessel and the proximal opening remains external to a patient’s skin. Related devices, kits, and methods are provided.

Abstract: Methods, devices, and systems establish and facilitate arterial access for interventional procedures, such as stenting, angioplasty, grafting, replacement valve therapy, and atherectomy.