Patents by Inventor Bradford Goodwin

Bradford Goodwin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of hyperproliferative diseases with vinca alkaloid N-oxide analogs
    Patent number: 8883775
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: November 11, 2014
    Assignee: Cascade Prodrug Inc.
    Inventors: John G. Curd, John F. W. Keana, Alshad S. Lalani, Paul B. Westberg, Bradford Goodwin, W. David Henner
  • Treatment of Hyperproliferative Diseases with Vinca Alkaloid N-Oxide Analogs
    Publication number: 20120107230
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Application
    Filed: October 25, 2011
    Publication date: May 3, 2012
    Applicants: UNIVERSITY OF OREGON
    Inventors: JOHN G. CURD, JOHN F.W. KEANA, ALSHAD S. LALANI, PAUL B. WESTBERG, BRADFORD GOODWIN, W. DAVID HENNER
  • Treatment of hyperproliferative diseases with vinca alkaloid N-oxide and analogs
    Patent number: 8048872
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: November 1, 2011
    Assignee: Stat of Oregon Acting by and Through The Oregon State Board of Higher Education on Behalf of the University of Oregon
    Inventors: John G. Curd, John F. W. Keana, Alshad S. Lalani, Paul B. Westberg, Bradford Goodwin, W. David Henner
  • Treatment of Hyperproliferative Diseases with Vinca Alkaloid N-Oxide and Analogs
    Publication number: 20080305075
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Application
    Filed: April 29, 2008
    Publication date: December 11, 2008
    Inventors: John G. Curd, John F.W. Keana, Alshad S. Lalani, Paul B. Westberg, Bradford Goodwin, W. David Henner
  • Prevention of Thrombotic Disorders with Active Vitamin D Compounds or Mimics Thereof
    Publication number: 20080069814
    Abstract: The present invention relates to a method for preventing, treating, or ameliorating thrombotic disorders in an animal comprising administering to the animal an active vitamin D compound or a mimic thereof. According to the invention, the active vitamin D compound or the mimic thereof may be administered by HDPA so that high doses of the active vitamin D compound or the mimic thereof can be administered to an animal without inducing severe symptomatic hypercalcemia. The invention also relates a method for preventing, treating, or ameliorating thrombotic disorders in an animal comprising administering to the animal an active vitamin D compound or a mimic thereof in combination with one or more other therapeutic agents.
    Type: Application
    Filed: March 26, 2007
    Publication date: March 20, 2008
    Inventors: John CURD, William HENNER, Tomasz BEER, Bradford GOODWIN, Alshad LALANI
  • Prevention of Arterial Restenosis with Active Vitamin D Compounds
    Publication number: 20070148205
    Abstract: The present invention relates to a method for preventing, treating, or ameliorating arterial restenosis after angioplasty in an animal by administering to the animal active vitamin D compounds. The invention further relates to a method for preventing, treating, or ameliorating restenosis after angioplasty in an animal by administering to the animal active vitamin D compounds in combination with other therapeutic agents. A further aspect of the invention is a method for preventing, treating, or ameliorating stenosis within and/or around an arterial bypass graft in an animal comprising administering to the animal an active vitamin D compound.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 28, 2007
    Inventors: Martha Whitehouse, Bradford Goodwin
  • Prevention of arterial restenosis with active vitamin d compounds
    Publication number: 20070142339
    Abstract: The present invention relates to a method for preventing, treating, or ameliorating arterial restenosis after angioplasty in an animal by administering to the animal active vitamin D compounds. The invention further relates to a method for preventing, treating, or ameliorating restenosis after angioplasty in an animal by administering to the animal active vitamin D compounds in combination with other therapeutic agents. A further aspect of the invention is a method for preventing, treating, or ameliorating stenosis within and/or around an arterial bypass graft in an animal comprising administering to the animal an active vitamin D compound.
    Type: Application
    Filed: May 10, 2005
    Publication date: June 21, 2007
    Applicant: Novacea, Inc.
    Inventors: Martha Whitehouse, Bradford Goodwin
  • Prevention of thrombotic disorders with active vitamin D compounds or mimics thereof
    Publication number: 20070037779
    Abstract: The present invention relates to a method for preventing, treating, or ameliorating thrombotic disorders in an animal comprising administering to the animal an active vitamin D compound or a mimic thereof. According to the invention, the active vitamin D compound or the mimic thereof may be administered by HDPA so that high doses of the active vitamin D compound or the mimic thereof can be administered to an animal without inducing severe symptomatic hypercalcemia. The invention also relates a method for preventing, treating, or ameliorating thrombotic disorders in an animal comprising administering to the animal an active vitamin D compound or a mimic thereof in combination with one or more other therapeutic agents.
    Type: Application
    Filed: July 7, 2006
    Publication date: February 15, 2007
    Inventors: John Curd, William Henner, Tomasz Beer, Bradford Goodwin