Patents by Inventor Bradford Stadler

Bradford Stadler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Interspersed repetitive element RNAs as substrates, inhibitors and delivery vehicles for RNAi
    Publication number: 20050186589
    Abstract: The present invention provides methods for identifying druggable targets in assays that feature compositions, cells and/or organisms having interspersed repetitive element (IRE) RNAs and an RNA interference (RNAi) pathway. Methods for identifying therapeutic agents and creating vaccines are also featured. The invention further provides methods for inhibiting RNAi involving IRE RNAs or inhibitory derivatives thereof. The invention also provides compositions for delivering siRNA and miRNA molecules derived from IRE loci and methods of use thereof. Therapeutic methods are also featured.
    Type: Application
    Filed: November 8, 2004
    Publication date: August 25, 2005
    Applicant: UNIVERSITY OF MASSACHUSETTS
    Inventors: Timothy Kowalik, Bradford Stadler
  • Virally-encoded RNAs as substrates, inhibitors and delivery vehicles for RNAi
    Publication number: 20050171041
    Abstract: The present invention provides methods for identifying druggable targets in assays that feature compositions, cells and/or organisms having structured viral non-coding RNAs (svRNAs) and an RNA interference (RNAi) pathway. Methods for identifying antiviral agents and creating vaccines are also featured. The invention further provides methods for inhibiting RNAi involving svRNAs or inhibitory derivatives thereof. The invention also provides compositions for delivering siRNA and miRNA molecules derived from svRNA loci and methods of use thereof. Therapeutic methods are also featured.
    Type: Application
    Filed: August 23, 2004
    Publication date: August 4, 2005
    Applicant: UNIVERSITY OF MASSACHUSETTS
    Inventors: Timothy Kowalik, Bradford Stadler