Patents by Inventor Bradford W. Baer

Bradford W. Baer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electroporation apparatus and process
    Patent number: 5128257
    Abstract: Process and apparatus for electroporation of cell suspensions and cells adhered to a surface wherein at least two simultaneous and directionally distinct electric impulses are used to transfect a biological substance into a cell.
    Type: Grant
    Filed: August 31, 1987
    Date of Patent: July 7, 1992
    Inventor: Bradford W. Baer
  • Method and nucleic acid for the preparation of lecithin:cholesterol acyltransferase
    Patent number: 5049488
    Abstract: Nucleic acid encoding lecithin:cholesterol acyltransferase is ligated into expression vectors and used to transform host cells for the synthesis of lecithin:cholesterol acyltransferase in recombinant cell culture. Lecithin:cholesterol acyltransferase amino acid sequence variants are described for enhancing the properties of lecithin:cholesterol acyltransferase. Lecithin:cholesterol acyltransferase and its variants are employed in the therapy of conditions characterized by hypercholesterolemia and for the mobilization of cholesterol in vivo.
    Type: Grant
    Filed: November 8, 1985
    Date of Patent: September 17, 1991
    Assignee: Genentech, Inc.
    Inventors: Bradford W. Baer, Dennis T. Drayna, Richard M. Lawn, John W. McLean