Abstract: A drilling system, assembly, and method may help optimize drilling in a system that involves more than one rotary tool that engages the formation. A rotary tool may be a rotary cutting tool, such as a drill bit or reamer, or some other rotary tool (e.g. stabilizer or rotary steerable tool) that has the potential to drag on the wall of the hole being drilled and take energy away from cutting. In an example, a wellbore or portion thereof is formed by rotating a first rotary cutting tool having a first cutting structure in engagement with one portion of the formation together with a second rotary cutting tool having a second cutting structure in engagement with another portion of the formation. Forces are obtained above and below the second cutting structure. One or more drilling parameter or drill bit design parameter are adjusted in relation to a force differential between the forces above and below the second cutting structure.

Abstract: Described are techniques and systems for secure camera based IMU calibration for stationary systems, including vehicles. Existing vehicle camera systems are employed, with enhanced security to prevent malicious attempts by hackers to try and cause a vehicle to enter IMU calibration mode. IMU calibration occurs when a calibration system determines the vehicle is parked in a controlled environment; calibration targets are positioned at different viewing angles to vehicle cameras to act as sources of optical patterns of encoded data. Features of the patterns are for security as well as for alignment functionality. Images of the calibration targets enable inference of a vehicle coordinate system, from which calculations for IMU mounting error compensations are performed. A relative rotation between the IMU and the vehicle coordinate system are applied to IMU data to compensate for relative rotations between the vehicle and the IMU, thereby improving vehicle slope and bank metrics.

Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.

Abstract: In an example, a method for assembly of a modular cable connector includes, at an end effector of a robotic insertion system, holding a cable insert module for insertion into a module slot of a module retainer. Two or more images are captured of the module retainer. Image processing is performed to identify a segmented image region corresponding to the module retainer and a virtual plane parallel to a face of the module retainer. The end effector is moved to an alignment pose determined based, at least in part, on the segmented image region and the virtual plane. The end effector is moved from the alignment pose toward an insertion pose. Upon insertion of the cable insert module into the module slot of the module retainer, the cable insert module is released from the end effector.

Abstract: A cable connector assembly includes a module retainer and a set of two or more cable insert modules sized and shaped for removable retention within two or more module slots of the module retainer. A cable insert module of the set of two or more cable insert modules includes a cable insertion recess sized and shaped for insertion of a cable wire of a cable, a connectivity interface on an opposing face of the cable insert module, and a transmission path between the cable insertion recess and the connectivity interface.

Abstract: Threaded implants, methods of delivering the implants and methods of manufacturing the implants. The threaded implants may be sized, configured and adapted for pelvic stabilization, and may include an elongate body that is optionally monolithic and has a distal end, a proximal end, and a length from the proximal end to the distal end.

Abstract: A fluid pump includes a pump element in communication with an inlet and an outlet. Rotation of the pump element generates a suction at the inlet and pressure at the outlet. The suction and pressure cooperate to move a fluid through a fluid path. An accessory fluid path is in communication with the inlet and outlet. The accessory fluid path includes a thermistor in communication with the accessory fluid path. The thermistor monitors a temperature of the fluid within the accessory fluid path.

Abstract: Disclosed herein are embodiments of a method and system for determining a critical torque on bit to reduce the occurrence of high frequency torsional oscillation (HFTO). In one embodiment, a method includes detecting at least one drilling parameter of an offset drill bit for a type of drilling system during an offset drilling operation using at least one in-bit sensor; determining a critical torque on bit (TOB) that is to excite HFTO of the offset drill bit based on the at least one drilling parameter and based on the type of drilling system; measuring, for a current drilling operation, a current TOB and a current weight on bit (WOB) of a current drill bit having a same type of drilling system as the type of drilling system for the offset drilling operation; determining whether current TOB exceeds critical TOB; and mitigating the HFTO for the current drill bit.

Abstract: A fixed cutter drill bit may include a bit body defining a bit axis and having a plurality of blades extending therefrom. A plurality of cutters are secured to the blades at different circumferential positions relative to the bit axis. Each cutter may define a cutter sweep profile as the bit body rotates about the bit axis. One or more of the cutters may form overlapping cutter sweep profiles to define a kerf therebetween. The cutters include a shaped cutter comprising a cutting face and a shaped portion on the cutting face aligned for engaging and removing the kerf.

Abstract: Some implementations include a method for eliminating bias in strain data produced by one or more strain gauges in a drill bit of a drill string. The method may include drilling a borehole with the drill bit. The method may include determining a bias in strain data based on drilling parameters detected during the drilling. The method may include removing the bias from a biased downhole drill bit measurement to indicate an unbiased downhole drill bit measurement.

Abstract: Disclosed in some examples are methods, systems, devices, and machine-readable mediums which monitor for file system element transfers to and from both the endpoint and authorized accounts on network-based service providers (e.g., cloud-based storage). The system uses the capabilities of monitoring both the network-based service and the client computing device to filter out legitimate uploads to authorized network-based services and legitimate downloads to authorized computing devices. By matching events, it filters out events that are likely legitimate, the system may provide more accurate information, notifications, awareness, and unmatched event indications.

Abstract: An airframe design may include a frame or assembly, and one or more components that may be removably attached to the frame. The frame may include struts, central bulkheads, a tail section, a plurality of wing sections, and motor mounts that are attached together. The one or more attachable components may include a forward fuselage, motors, propellers, motor pod fairings, stabilizer fins, and landing gear that are attached using fasteners. The frame may reduce the number of parts of the airframe design and may also reduce complexity, cost, and weight, while also increasing stiffness and strength. Further, the various attachable components may facilitate fabrication, assembly, and maintenance of an aerial vehicle having the airframe design.

Abstract: An autonomous vehicle including a vehicle propulsion system, a braking system, a steering system, and a computing system. The computing system includes a processor and memory that stores computer-executable instructions that cause the processor to select a route for a passenger of the autonomous vehicle for a trip to a destination. The route for the passenger is selected from a plurality of potential routes. The route for the passenger is selected based on a preference of the passenger and aggregate ride quality feedback from passengers of autonomous vehicles in a fleet at locations along the potential routes to the destination. The processor is further configured to control at least one of the vehicle propulsion system, the braking system, or the steering system to move the autonomous vehicle along the route as selected for the trip to the destination.

Abstract: A small bone internal fixation system for orthopedic surgery is disclosed. This includes a fixation plate which is fixated to the bone before making the osteotomy cut of the head from the bone and can act as a cut guide for the cutting action. A buttress portion on a side of the fixation plate provides a front buttress surface which acts as the cutting guide and locates the translational movement of the cut head so as to prevent the metatarsal or metacarpal bone head from swiveling as it translates and allows for an easy method of temporarily and then permanently fixating the metatarsal or metacarpal head using firstly a wire guide and then a screw guided by the wire which fastens the bone head to the buttress portion.

Abstract: A system may include a strain gauge bar securable within a puck recess formed in an outer surface of a downhole drill bit. The strain gauge bar may be configured to collect data indicating a downhole force applied to the downhole drill bit during drilling operations. Further, the strain gauge bar may have a body portion and at least one wedge feature protruding from the body portion. The at least one wedge feature may be insertable into at least one wedge recess formed in the bottom surface of the puck recess. The system may also include a strain puck cap securable within the puck recess. The strain puck cap may be configured to apply pressure to the strain gauge bar to drive the at least one wedge feature of the strain gauge bar into the at least one wedge recess and pre-load the strain gauge bar.

Abstract: An airframe design may include a bonded frame or assembly, and one or more components that may be removably attached to the bonded frame. The bonded frame may include struts, central bulkheads, a tail section, a plurality of wing sections, and motor mounts that are adhered together using adhesive. The one or more attachable components may include a forward fuselage, motors, propellers, motor pod fairings, stabilizer fins, and landing gear that are attached using fasteners. The bonded frame may reduce the number of parts of the airframe design and may also reduce complexity, cost, and weight, while also increasing stiffness and strength. Further, the various attachable components may facilitate fabrication, assembly, and maintenance of an aerial vehicle having the airframe design.

Abstract: A method for downhole cutting structure design. The method comprises executing a first computer-simulated drilling by at least one downhole cutting structure of a wellbore into a subsurface formation based on an original data set that includes at least one drilling parameter and at least one downhole cutting structure attribute associated with an actual drilling of the wellbore using the at least one downhole cutting structure into the subsurface formation. The method comprises recursively performing the following operations until a drilling performance threshold is satisfied, changing at least one of the at least one drilling parameter and the at least one downhole cutting structure attribute in the original data set to create a modified data set and executing a second computer-simulated drilling by the at least one downhole cutting structure of the wellbore into the subsurface formation based and the modified data set.

Abstract: Disclosed are methods of synthesizing poly(ester urea)s.

Abstract: Disclosed in some examples are methods, systems, devices, and machine-readable mediums which monitor for file system element transfers to and from both the endpoint and authorized accounts on network-based service providers (e.g., cloud-based storage). The system uses the capabilities of monitoring both the network-based service and the client computing device to filter out legitimate uploads to authorized network-based services and legitimate downloads to authorized computing devices. By matching events, it filters out events that are likely legitimate, the system may provide more accurate information, notifications, awareness, and unmatched event indications.