Patents by Inventor Bradley Brasher

Bradley Brasher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination therapy for the treatment of immunoinflammatory disorders
    Publication number: 20070110685
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non-steroidal immunophilin-dependent immunosuppressant (NsIDI) and a Group A enhancer (e.g., antifungal agent, antigout agent, anti-infective agent, antiprotozoal agent, antiviral agent, humectant, sunscreen, vitamin D compound, microtubuline inhibitor, or zinc salt) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and Group A enhancer or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: June 16, 2006
    Publication date: May 17, 2007
    Inventors: Benjamin Auspitz, Bradley Brasher, Todd Chappell, Michael Frank, Daniel Grau, Edward Jost-Price, Seth Lederman, Palaniyandi Manivasakam, Seth Orlow, Noah Sachs, Brendan Smith
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20050192261
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient an antihistamine, either alone or in combination with one or more additional agents. The invention also features a pharmaceutical composition containing an antihistamine in combination with one or more additional agents.
    Type: Application
    Filed: September 14, 2004
    Publication date: September 1, 2005
    Inventors: Edward Jost-Price, Palaniyandi Manivasakam, Bradley Brasher, Brendan Smith, Noah Sachs, Benjamin Auspitz, Todd Chappell, Micheal Slavonic
  • Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
    Publication number: 20050153947
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering an SSRI or analog or metabolite thereof and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing an SSRI or analog or metabolite thereof and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: September 20, 2004
    Publication date: July 14, 2005
    Inventors: Mahesh Padval, Edward Jost-Price, Palaniyandi Manivasakam, Brendan Smith, Jason Fong, Benjamin Auspitz, M. Nichols, Curtis Keith, Grant Zimmerman, Bradley Brasher, Noah Sachs, Todd Chappell
  • Methods and compositions for identifying peptide aptamers capable of altering a cell phenotype
    Publication number: 20050053970
    Abstract: The invention provides methods and compositions for screening and identifying of peptide aptamers that can modulate a cell phenotype and further, can be used for the treatment of a disease involving a misregulated cell phenotype, such as, for example, a cancer. The invention encompasses methods and compositions for producing cyclic peptide aptamers, including peptide aptamers comprising a conotoxin sequence, having improved stability and bioactivity. The invention also provides methods and compositions for improved gene delivery and expression of a peptide aptamer in cell.
    Type: Application
    Filed: April 28, 2004
    Publication date: March 10, 2005
    Inventors: John Benson, Sylvie Vincent, Bradley Brasher, Zhenwei Miao, Dudley Lamming